DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and Ppic

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_001004215.1	Gene:	Ppic / 291463	RGDID:	1303221	Length:	212	Species:	Rattus norvegicus

Alignment Length:	191	Identity:	81/191 - (42%)
Similarity:	110/191 - (57%)	Gaps:	13/191 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VKSTNPL----VYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTK 70
            |:...||    |:.|:.||.:|.||::|.|...|||:|.|||..|.|||.|.|       |||:.
  Rat    29 VRKRGPLVTDKVFFDVRIGDKDVGRIVIGLFGKVVPRTVENFVTLATGEKGYG-------YKGSI 86

  Fly    71 FHKIKRVFVVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISA 135
            ||::.:.|::|.||....||:.|.||||..|.||||:|.|...|.|||||.| |::|.|||||:.
  Rat    87 FHRVIKDFMIQGGDFTARDGTGGMSIYGETFPDENFKLKHYGIGWVSMANAG-PDTNGSQFFITL 150

  Fly   136 AGCENLNGTNVVVGRVLRGLGIVAEMEQNCTDEGD-PTAPIVIRDCGEIAHNEDWGIECND 195
            .....|:|.:||.|:||.|:.:|..:|...||:.| |.....|.:.|:|.....:.:|..|
  Rat   151 TKPAWLDGKHVVFGKVLDGMTVVHSIELQATDDHDRPLTDCTIVNSGKIDVKTPFVVEVPD 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	76/170 (45%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
Ppic	NP_001004215.1	cyclophilin_ABH_like	38..197	CDD:238907	74/166 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339737
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840