Protein Alignment Cyp40 and rct1

DIOPT Version :10

• Sequence 1: NP_648338.1
• Gene: Cyp40 / 39121
• FlyBaseID: FBgn0036020
• Length: 383
• Species: Drosophila melanogaster
• Sequence 2: NP_595894.1
• Gene: rct1 / 2539942
• PomBaseID: SPBC17G9.05
• Length: 432
• Species: Schizosaccharomyces pombe
• Alignment Length: 386
• Identity: 83/386 - (21%)
• Similarity: 146/386 - (37%)
• Gaps: 108/386 - (27%)

  Fly    29 GRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRVFVVQSGDVVKNDGSSG 93
            |.::|:|.....|||.|||..||          |..:|....|:.|:..:..|:||.:...|..|
pombe    10 GDLVIDLFVKEAPKTCENFLKLC----------KLKYYNFCPFYNIQHNYTCQTGDPLGPTGDGG 64

  Fly    94 ESIYGPV------FDDE-NFELSHNEEGVVSMANYGKPNSNN------SQFFISAAGCENLNGTN 145
            ..::..:      |..| |..|.||:.|:|||:.....:.::      |||.|:.:  :||.|.:
pombe    65 RCVWNVLNKGTRFFKAEFNPSLVHNKMGLVSMSTATISSRDDKLLVCGSQFIITLS--DNLEGLD 127

  Fly   146 ---VVVGRVLRGLGIVAEM-EQNCTDEGDPTAPIVIR-------------DCGE----------- 182
               .:.|:|..|...:.:: :..|.:||.|...|.|:             |..|
pombe   128 ERYPIYGQVAEGFDTLLKINDAICDEEGQPYRDIRIKHTIILDDPFEDPPDLVEPLRSPSPTPEQ 192

  Fly   183 -----IAHNEDWGIECNDETTDK------------------LP----AYPQD--WPRKLDKFTGD 218
                 |..||....|.:::...:                  ||    |.|::  :..||:..|.|
pombe   193 LATVRIGENEQIESETSEDKLQREKEMEAEAEAVTLEMIGDLPFAHVAPPENVLFVCKLNPVTQD 257

  Fly   219 GAVELLTGIRQSGNHFYQLGRY---HEARAKYRKANRYYHYL---SRQFGWQQLNPLKKHLVDED 277
            ..:||:         |.:.|:.   ...|.|....:..|.::   :::...:....::..|:|:.
pombe   258 EDLELI---------FSRFGKIISCQVIRDKETGDSLQYAFIEFDNKESVEKAYFKMQNVLIDDS 313

  Fly   278 LLKVDGFSVVNNINAAAVDLKVGNYTSAREVCNEAIRLDPKCSKAFYRRAQAQRGLRNYEE 338
            .:.|| ||       .:|......|.|.|:....:.|.|   .:.::||:..:....||.:
pombe   314 RIHVD-FS-------QSVARYRQYYNSNRDRKRSSSRSD---DREYHRRSDGRYDRSNYRD 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp40	NP_648338.1	cyclophilin	15..181	CDD:469651	47/181 (26%)
		TPR	231..>370	CDD:440225	21/114 (18%)
		TPR repeat	285..315	CDD:276809	5/29 (17%)
		TPR repeat	320..346	CDD:276809	4/19 (21%)
rct1	NP_595894.1	cyclophilin_RRM	4..176	CDD:238902	46/177 (26%)
		RRM_PPIL4	241..323	CDD:409681	18/98 (18%)