DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and Ppig

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_001074555.1	Gene:	Ppig / 228005	MGIID:	2445173	Length:	752	Species:	Mus musculus

Alignment Length:	176	Identity:	83/176 - (47%)
Similarity:	114/176 - (64%)	Gaps:	3/176 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VKSTNPLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIG-TLGKPLHYKGTKFHK 73
            :|...|..:.||:|..:.|||::.||..||.|||.||||.|||||.|.| :..||||||...||:
Mouse     3 IKVQRPRCFFDIAINNQPAGRVVFELFSDVCPKTCENFRCLCTGEKGTGKSTQKPLHYKSCLFHR 67

  Fly    74 IKRVFVVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGC 138
            :.:.|:||.||..:.:|..||||||..|:||:|.:.||:|.::||||.|| ::|.|||||:....
Mouse    68 VVKDFMVQGGDFSEGNGRGGESIYGGFFEDESFAVKHNKEFLLSMANRGK-DTNGSQFFITTKPT 131

  Fly   139 ENLNGTNVVVGRVLRGLGIVAEMEQNCTDEGD-PTAPIVIRDCGEI 183
            .:|:|.:||.|:|:.|..:|.|:|...||... |.|.:.|..|||:
Mouse   132 PHLDGHHVVFGQVISGQEVVREIENQKTDAASKPFAEVRILSCGEL 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	79/167 (47%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
Ppig	NP_001074555.1	cyclophilin	8..175	CDD:412213	79/167 (47%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	182..752
		PTZ00121	<401..750	CDD:173412
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836081
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740