DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and cyn-3

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_506751.1	Gene:	cyn-3 / 180028	WormBaseID:	WBGene00000879	Length:	173	Species:	Caenorhabditis elegans

Alignment Length:	167	Identity:	89/167 - (53%)
Similarity:	117/167 - (70%)	Gaps:	1/167 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRVFVVQ 81
            |:.||:||.:.:||:::||..|||||||.|||||||||.|||..|||||:||:|||:|...|::|
Worm     6 VFFDITIGGKASGRIVMELYDDVVPKTAGNFRALCTGENGIGKSGKPLHFKGSKFHRIIPNFMIQ 70

  Fly    82 SGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLNGTNV 146
            .||..:.:|:.||||||..|.||||:..|...||:||||.| ||:|.||||:.....|.|:|.:|
Worm    71 GGDFTRGNGTGGESIYGEKFPDENFKEKHTGPGVLSMANAG-PNTNGSQFFLCTVKTEWLDGKHV 134

  Fly   147 VVGRVLRGLGIVAEMEQNCTDEGDPTAPIVIRDCGEI 183
            |.|||:.||.:|..:|.|.:..|.|....:|.|||::
Worm   135 VFGRVVEGLDVVKAVESNGSQSGKPVKDCMIADCGQL 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	87/163 (53%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
cyn-3	NP_506751.1	cyclophilin_ABH_like	4..169	CDD:238907	87/163 (53%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11071
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920