DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and cyn-4

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_496337.1	Gene:	cyn-4 / 174674	WormBaseID:	WBGene00000880	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	152	Identity:	55/152 - (36%)
Similarity:	80/152 - (52%)	Gaps:	15/152 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 GRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRVFVVQSGDVVKNDGSSG 93
            |.:.:||....|||..|||...|:..          :|..||||::.:.|::|.||.. ..|..|
Worm   289 GPLNLELFAPKVPKACENFITHCSNG----------YYNNTKFHRLIKNFMLQGGDPT-GTGHGG 342

  Fly    94 ESIYGPVFDDENFE-LSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLNGTNVVVGRVLRGLGI 157
            |||:...|.||... .||:..||:||||.|. |:|.|||||:...|:.|:..:.:.||::.|...
Worm   343 ESIWDKPFSDEFISGFSHDARGVLSMANKGS-NTNGSQFFITFRPCKYLDRKHTIFGRLVGGQDT 406

  Fly   158 VAEMEQNCTDEGD--PTAPIVI 177
            :..:|:..|:||.  |...:||
Worm   407 LTTIEKLETEEGTDVPMVSVVI 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	55/152 (36%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
cyn-4	NP_496337.1	Ubox	45..96	CDD:128780
cyn-4	NP_496337.1	cyclophilin_RING	281..440	CDD:238904	55/152 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810