DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and cyn-5

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_001379232.1	Gene:	cyn-5 / 173374	WormBaseID:	WBGene00000881	Length:	204	Species:	Caenorhabditis elegans

Alignment Length:	177	Identity:	72/177 - (40%)
Similarity:	101/177 - (57%)	Gaps:	9/177 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 VYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKRVFVVQ 81
            ||.|:.||.:..||::|.|....|||||.||..|.....|.|       |.|:|||::...|::|
Worm    31 VYFDMEIGGKPIGRIVIGLFGKTVPKTATNFIELAKKPKGEG-------YPGSKFHRVIADFMIQ 88

  Fly    82 SGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLNGTNV 146
            .||..:.||:.|.||||..|.||||:|.|...|.:||||.| .::|.|||||:......|:|.:|
Worm    89 GGDFTRGDGTGGRSIYGEKFADENFKLKHYGAGWLSMANAG-ADTNGSQFFITTVKTPWLDGRHV 152

  Fly   147 VVGRVLRGLGIVAEMEQNCTDEGD-PTAPIVIRDCGEIAHNEDWGIE 192
            |.|::|.|:.:|.::||.....|| |...::|...|.||.:..:.:|
Worm   153 VFGKILEGMDVVRKIEQTEKLPGDRPKQDVIIAASGHIAVDTPFSVE 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	68/164 (41%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
cyn-5	NP_001379232.1	cyclophilin	29..188	CDD:412213	68/164 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820