DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and PPIF

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	NP_005720.1	Gene:	PPIF / 10105	HGNCID:	9259	Length:	207	Species:	Homo sapiens

Alignment Length:	173	Identity:	84/173 - (48%)
Similarity:	113/173 - (65%)	Gaps:	8/173 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 STNPLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTLGKPLHYKGTKFHKIKR 76
            |.|||||||:....:..||:::||:.|||||||||||||||||.|.|       |||:.||::..
Human    43 SGNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFG-------YKGSTFHRVIP 100

  Fly    77 VFVVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENL 141
            .|:.|:||...::|:.|:||||..|.||||.|.|...||:||||.| ||:|.|||||.....:.|
Human   101 SFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAG-PNTNGSQFFICTIKTDWL 164

  Fly   142 NGTNVVVGRVLRGLGIVAEMEQNCTDEGDPTAPIVIRDCGEIA 184
            :|.:||.|.|..|:.:|.::|...:..|..:..|||.|||:::
Human   165 DGKHVVFGHVKEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	80/165 (48%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
PPIF	NP_005720.1	cyclophilin_ABH_like	46..204	CDD:238907	80/165 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820