DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and Nktr

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	XP_038938667.1	Gene:	Nktr / 100364165	RGDID:	2321593	Length:	1516	Species:	Rattus norvegicus

Alignment Length:	311	Identity:	99/311 - (31%)
Similarity:	155/311 - (49%)	Gaps:	57/311 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 PLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIG-TLGKPLHYKGTKFHKIKRVF 78
            |..:.||.|.:|..||::.:|..|:.|||.:||..||:||.|:| |.||.|.|||:.||::.:.|
  Rat    66 PQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFHRVVKNF 130

  Fly    79 VVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLNG 143
            ::|.||..:.:|..||||||..|.||||.|.|:...::||||.|| ::|.|||||:.....:|:|
  Rat   131 MIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANRGK-HTNGSQFFITTKPAPHLDG 194

  Fly   144 TNVVVGRVLRGLGIVAEMEQNCTDEGD-PTAPIVIRDCGEIA----------------HNEDWGI 191
            .:||.|.|:.|..::.::|...||... |.|.:.:.|||.:|                |:||...
  Rat   195 VHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCGVLATKLTKDVFEKKRKKPTHSEDSDS 259

  Fly   192 ECNDETTDKLPAYPQDWPRKLDKFTGDGAVELLTGIRQSGNHFYQLGRYHEARAKYRKANRYYHY 256
            ..|..::              .:.:.:..|| ...||:         |.|:.|.|.|...:....
  Rat   260 SSNSSSS--------------SESSSESEVE-RERIRR---------RRHKRRPKVRHTKKRRKE 300

  Fly   257 LSRQFGWQQLNPLKKHLVDEDLLKVDGFSVVNNINAAAVDLKVGNYTSARE 307
            :|   |.::|.  :|..|..     :|:|..:::|    :.:.|:..:.||
  Rat   301 MS---GSEELR--RKRTVSP-----EGYSERSDVN----EKRSGDSNTKRE 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	72/167 (43%)
		TPR repeat	285..315	CDD:276809	5/23 (22%)
		TPR_19	300..369	CDD:291240	3/8 (38%)
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
Nktr	XP_038938667.1	cyclophilin	66..233	CDD:412213	72/167 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339735
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940