Protein Alignment Cyp40 and Nktr

DIOPT Version :10

• Sequence 1: NP_648338.1
• Gene: Cyp40 / 39121
• FlyBaseID: FBgn0036020
• Length: 383
• Species: Drosophila melanogaster
• Sequence 2: XP_038938667.1
• Gene: Nktr / 100364165
• RGDID: 2321593
• Length: 1516
• Species: Rattus norvegicus
• Alignment Length: 311
• Identity: 99/311 - (31%)
• Similarity: 155/311 - (49%)
• Gaps: 57/311 - (18%)

  Fly    15 PLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIG-TLGKPLHYKGTKFHKIKRVF 78
            |..:.||.|.:|..||::.:|..|:.|||.:||..||:||.|:| |.||.|.|||:.||::.:.|
  Rat    66 PQCHFDIEINREPVGRIMFQLFSDICPKTCKNFLCLCSGEKGLGKTTGKKLCYKGSTFHRVVKNF 130

  Fly    79 VVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCENLNG 143
            ::|.||..:.:|..||||||..|.||||.|.|:...::||||.|| ::|.|||||:.....:|:|
  Rat   131 MIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANRGK-HTNGSQFFITTKPAPHLDG 194

  Fly   144 TNVVVGRVLRGLGIVAEMEQNCTDEGD-PTAPIVIRDCGEIA----------------HNEDWGI 191
            .:||.|.|:.|..::.::|...||... |.|.:.:.|||.:|                |:||...
  Rat   195 VHVVFGLVISGFEVIEQIENLKTDAASRPYADVRVIDCGVLATKLTKDVFEKKRKKPTHSEDSDS 259

  Fly   192 ECNDETTDKLPAYPQDWPRKLDKFTGDGAVELLTGIRQSGNHFYQLGRYHEARAKYRKANRYYHY 256
            ..|..::              .:.:.:..|| ...||:         |.|:.|.|.|...:....
  Rat   260 SSNSSSS--------------SESSSESEVE-RERIRR---------RRHKRRPKVRHTKKRRKE 300

  Fly   257 LSRQFGWQQLNPLKKHLVDEDLLKVDGFSVVNNINAAAVDLKVGNYTSARE 307
            :|   |.::|.  :|..|..     :|:|..:::|    :.:.|:..:.||
  Rat   301 MS---GSEELR--RKRTVSP-----EGYSERSDVN----EKRSGDSNTKRE 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp40	NP_648338.1	cyclophilin	15..181	CDD:469651	72/167 (43%)
		TPR	231..>370	CDD:440225	16/77 (21%)
		TPR repeat	285..315	CDD:276809	5/23 (22%)
		TPR repeat	320..346	CDD:276809
Nktr	XP_038938667.1	cyclophilin	66..233	CDD:469651	72/167 (43%)