DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8336 and nktr

DIOPT Version :9

Sequence 1:	NP_001261636.1	Gene:	CG8336 / 39121	FlyBaseID:	FBgn0036020	Length:	383	Species:	Drosophila melanogaster
Sequence 2:	XP_002939352.1	Gene:	nktr / 100145676	XenbaseID:	XB-GENE-992970	Length:	1394	Species:	Xenopus tropicalis

Alignment Length:	262	Identity:	91/262 - (34%)
Similarity:	132/262 - (50%)	Gaps:	34/262 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KSTNPLVYLDISIGKEDAGRMIIELRKDVVPKTAENFRALCTGECGIGTL-GKPLHYKGTKFHKI 74
            :...|..|.|:.|.:|..||::.:|..||.|||..||..|||||.|||.: ||.|.|||:.||::
Frog     3 EKARPQCYFDVEINREPVGRIVFQLFSDVCPKTCMNFLCLCTGEKGIGKVTGKKLCYKGSTFHRV 67

  Fly    75 KRVFVVQSGDVVKNDGSSGESIYGPVFDDENFELSHNEEGVVSMANYGKPNSNNSQFFISAAGCE 139
            .:.|::|.||..:.:|..||||||..|.||||.|.|:...::||||.|| |:|.|||||:.....
Frog    68 VKNFMIQGGDFSEGNGKGGESIYGGYFKDENFILKHDRAFLLSMANRGK-NTNGSQFFITTKAAP 131

  Fly   140 NLNGTNVVVGRVLRGLGIVAEMEQNCTDEGD-PTAPIVIRDCGEI--------------AHNEDW 189
            :|:|.:||.|.|:.|..::.::|...||... |.|.:.:.|||.:              :.:||.
Frog   132 HLDGVHVVFGLVISGFEVIEQIESLKTDAASRPYADVRVIDCGLLVSKAAREEKIKRAASQSEDS 196

  Fly   190 GIECNDETTDKLPAYPQDWPRKLDKFTGDGAVEL----------LTGIRQSGNHFYQLGRYHEAR 244
            .......|    |:.|..   ..:..:.:...|:          .|.::.|.....:.||..|||
Frog   197 DSSLKSTT----PSSPSS---SSESTSSESEAEIERHRRKKRKRKTKVKHSKRRRKESGRKEEAR 254

  Fly   245 AK 246
            .|
Frog   255 EK 256

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8336	NP_001261636.1	cyclophilin	15..181	CDD:294131	75/167 (45%)
		TPR repeat	285..315	CDD:276809
		TPR_19	300..369	CDD:291240
		TPR_1	320..353	CDD:278916
		TPR repeat	320..346	CDD:276809
nktr	XP_002939352.1	cyclophilin	7..174	CDD:381853	75/167 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1403619at2759
OrthoFinder	1	1.000	-	-		FOG0000032
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920