DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3335 and PAB3

DIOPT Version :9

Sequence 1:	NP_648337.1	Gene:	CG3335 / 39119	FlyBaseID:	FBgn0036018	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_173690.1	Gene:	PAB3 / 838882	AraportID:	AT1G22760	Length:	660	Species:	Arabidopsis thaliana

Alignment Length:	339	Identity:	72/339 - (21%)
Similarity:	140/339 - (41%)	Gaps:	67/339 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   354 LSKEDD---ISESGRIFFRNLAYTTTEEDLRKLFEQFGPVVEVNLPLDKLTRKIKGFGTVTYMMP 415
            ||..|.   :|..|.||.:||..:...:.|.:.|..||.::...:.:| :|.:.||:|.|.:...
plant   123 LSNRDPSTRLSGKGNIFIKNLDASIDNKALFETFSSFGTILSCKVAMD-VTGRSKGYGFVQFEKE 186

  Fly   416 EHALKAFNTLDGTDFHGRLLHLLPSKDI-----EKNPKEDLDENDASLSFKEKKALKLKKNAQKP 475
            |.|..|.:.|:|.        |:..|.:     .:..:...|||..:..|.....    ||..|.
plant   187 ESAQAAIDKLNGM--------LMNDKQVFVGHFIRRQERARDENTPTPRFTNVYV----KNLPKE 239

  Fly   476 IGWNTL---FLGANAVAEILAKQFKTSKERI-----LDTSDGGSSAAVR---LALGETQVVI--- 526
            ||.:.|   |.....::..:..:.::...|.     .:.::..:||..:   ::||:..:.:
plant   240 IGEDELRKTFGKFGVISSAVVMRDQSGNSRCFGFVNFECTEAAASAVEKMNGISLGDDVLYVGRA 304

  Fly   527 --------EMKRFLEEEGVRLDAFDEPAKKRSNTVILAKNLPAATEISEITPIFSRFGPI--GRI 581
                    |::|..|:|  |::.|:    |.....:..|||..:.:..::..:||.:|.:  .::
plant   305 QKKSEREEELRRKFEQE--RINRFE----KSQGANLYLKNLDDSVDDEKLKEMFSEYGNVTSSKV 363

  Fly   582 VLPPSGVT---ALIEYCDPLEARQAFKKLAYSKFKNAPLYLEWAP---------EQVFTKTLSGE 634
            :|.|.|::   ..:.|.:|.||.:|..::........|||:..|.         :.:|::..:..
plant   364 MLNPQGMSRGFGFVAYSNPEEALRALSEMNGKMIGRKPLYIALAQRKEDRRAHLQALFSQIRAPG 428

  Fly   635 PVI----PKSEPKP 644
            |:.    |...|.|
plant   429 PMSGFHHPPGGPMP 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3335	NP_648337.1	RRM1_RBM19	2..77	CDD:241008
		RRM_SF	250..314	CDD:302621
		RRM3_RBM19	362..440	CDD:241011	21/77 (27%)
		RRM4_RBM19	552..623	CDD:241013	17/75 (23%)
		RRM	<638..845	CDD:223796	3/7 (43%)
		RRM5_RBM19_like	679..760	CDD:240764
		RRM6_RBM19	785..864	CDD:241015
PAB3	NP_173690.1	PABP-1234	49..644	CDD:130689	72/339 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910