DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3335 and CG34354

DIOPT Version :9

Sequence 1:	NP_648337.1	Gene:	CG3335 / 39119	FlyBaseID:	FBgn0036018	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_001097953.2	Gene:	CG34354 / 5740528	FlyBaseID:	FBgn0085383	Length:	550	Species:	Drosophila melanogaster

Alignment Length:	177	Identity:	41/177 - (23%)
Similarity:	72/177 - (40%)	Gaps:	27/177 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   716 PENPREFKSLGY--------GFIQFKKSSVAEHALKNLQLTHIDGNPVELKRSDRVLKTQDNDGA 772
            |..|.|.|.|..        ...|.::|..|.|...|.|..|      ..::..:.:..|.....
  Fly    25 PHKPPETKLLAIHPAAAAAAAAQQQQQSVTAAHLQHNGQQQH------SQQQQQQQMSQQQQQQQ 83

  Fly   773 QRRLASQKKQTGTKILVRNIPFQAQYREVRDIFKAFGELRSLRIPKKATTGEDAHRGFGFVDYMS 837
            |:.:.:..|.....|.|.::..:.:.::::|.|..|||:...|:.:...|.:.  :|:|||.::.
  Fly    84 QQLVGNNSKPEQFHIFVGDLSAEIETQQLKDAFTPFGEISDCRVVRDPQTLKS--KGYGFVSFVK 146

  Fly   838 KAEAKRAFDALSASTHLYGRRLVLEWSANDDNQDVEELRKRTAAKFD 884
            |:||:.|..|::.. .|..|.:...|:.          ||..|.|.|
  Fly   147 KSEAETAITAMNGQ-WLGSRSIRTNWAT----------RKPPATKAD 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3335	NP_648337.1	RRM1_RBM19	2..77	CDD:241008
		RRM_SF	250..314	CDD:302621
		RRM3_RBM19	362..440	CDD:241011
		RRM4_RBM19	552..623	CDD:241013
		RRM	<638..845	CDD:223796	31/136 (23%)
		RRM5_RBM19_like	679..760	CDD:240764	12/51 (24%)
		RRM6_RBM19	785..864	CDD:241015	20/78 (26%)
CG34354	NP_001097953.2	RRM2_TIA1_like	97..171	CDD:240799	20/76 (26%)
CG34354	NP_001097953.2	RRM3_TIA1_like	202..278	CDD:240800
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464024
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930