Protein Alignment CG3335 and rbm19

DIOPT Version :10

• Sequence 1: NP_648337.1
• Gene: CG3335 / 39119
• FlyBaseID: FBgn0036018
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: NP_944597.2
• Gene: rbm19 / 387255
• ZFINID: ZDB-GENE-031125-3
• Length: 927
• Species: Danio rerio
• Alignment Length: 978
• Identity: 381/978 - (38%)
• Similarity: 580/978 - (59%)
• Gaps: 112/978 - (11%)

  Fly     1 MSRIIVKQLPKHITEDKLRQIFGAQGTITDLQLKYTPDGKFRQFCFVGYSTEEEAQSAIRHFDNT 65
            |||:|||.||..:.||:.|::|...||:||..||:|.|||||:|.|||:.|||:||.|::||:.:
Zfish     1 MSRLIVKNLPNGMKEDRFRKMFADFGTLTDCALKFTKDGKFRKFGFVGFKTEEDAQKALKHFNKS 65

  Fly    66 CIQTSRVRVESCAALGSEDKPQSWSKYAK--DSKKNLDKLKEKEREAAAKAKESEKKKKKDKVDK 128
            .:.||||.||.|...|..:|.:.|||:.:  .|||:.::.|..|        :.||:|||.|  |
Zfish    66 FVDTSRVTVELCTDFGDPNKARPWSKHTRQPSSKKDTEEKKTHE--------QGEKEKKKPK--K 120

  Fly   129 VDQILSRHKDDPEFQEFLEAHDKSRTL--WGNDLGINKNRENEEEDDEEQEESRAARDD-SGVDA 190
            :..:|...:.|..|||||..|.|...:  |.||.........|.|..:|:::..|..|| ...|:
Zfish   121 ILNVLGDLEKDESFQEFLAVHQKRGQVPTWANDTVEATAVRPEMEKKKEKKQKAAVEDDYLNFDS 185

  Fly   191 DAGDE--DGSGDEADEE--EDTDKLAEKP-ISDLEYMKSLM------------------------ 226
            |..:|  |...|.||||  :|.:|.|.|. :||::|::|.|
Zfish   186 DESEESSDDGEDAADEEDKQDNEKEALKTGLSDMDYLRSKMVEKSDMLDEKDDDSSASAADENEE 250

  Fly   227 ----------------ATTSGEATAKKPKAKADKSNLELFTIKIHNVPYNTKRQEVLKFFKPLKP 275
                            |..|||.|:.:...:........||:|:...|:|.|.|:|.:|..||||
Zfish   251 DEGKEEEESIVQHADSAYESGEKTSSQKSTRPAIEPTTEFTVKLRGAPFNVKEQQVKEFMMPLKP 315

  Fly   276 YSVRL----PSKVHGFCYVGFKTEKDMAKGMLKNKSFIKGK--QVF-FSDFTEKNKVTKASKSGQ 333
            .::|.    ..:..|:.||..::|.::.:.:..:|.::.|:  :|| .::|....:..|.|:..:
Zfish   316 VAIRFAKNSDGRNSGYVYVDLRSEAEVERALRLDKDYMGGRYIEVFRANNFKNDRRSAKRSEMEK 380

  Fly   334 PLAPAAVDAGNAKWKHQQDSLSKEDDISESGRIFFRNLAYTTTEEDLRKLFEQFGPVVEVNLPLD 398
            .......|.            .:|:|::||||:|.||:.||.|||||:::|.:.||:.||..|:|
Zfish   381 NFVRELKDD------------EEEEDVAESGRLFIRNMPYTCTEEDLKEVFSKHGPLSEVLFPID 433

  Fly   399 KLTRKIKGFGTVTYMMPEHALKAFNTLDGTDFHGRLLHLLPSKDIEKNPKEDLDENDASLSFKEK 463
            .||:|.|||..||||:||:|:.|...|||..|.||:||::.|: ::|...:...:...|.|:|.|
Zfish   434 SLTKKPKGFAFVTYMIPENAVSALAQLDGHTFQGRVLHVMASR-LKKEKADQGPDAPGSSSYKRK 497

  Fly   464 KALKLKKNAQKPIGWNTLFLGANAVAEILAKQFKTSKERILD-TSDGGSSAAVRLALGETQVVIE 527
            |..|.|..:.....|||||||.:|||:.:|:::.|:|.::|| .|||  |.|||:||||||:|.|
Zfish   498 KDAKDKAASGSSHNWNTLFLGTSAVADAIAEKYNTTKSQVLDHESDG--SLAVRMALGETQIVQE 560

  Fly   528 MKRFLEEEGVRLDAFDEPAKKRSNTVILAKNLPAATEISEITPIFSRFGPIGRIVLPPSGVTALI 592
            .::||.:.||.||:|.:.:.:||..|||.||||:..:::::..:||..|.:||::|||||:||::
Zfish   561 TRQFLLDNGVSLDSFSQASGERSKCVILVKNLPSGVQVADLEALFSPHGSLGRVLLPPSGLTAIV 625

  Fly   593 EYCDPLEARQAFKKLAYSKFKNAPLYLEWAPEQVFTKTLSGEPVIPKSEPKPKEEVKPEEKPIVN 657
            |:.:|.||::||.||||:||::.||||||||..|||     .|..|:.||:.|     |:..:.|
Zfish   626 EFLEPTEAKRAFMKLAYTKFQHVPLYLEWAPVAVFT-----TPSAPRPEPQTK-----EKSAVKN 680

  Fly   658 DAKPDEEDSRAEDADDEPEPNTTLFLRNLNFKTVQETVEKHFRHLGSIHTVEIAKRRDPENPREF 722
            |:..:||:...|:.||:..|.:|||::||||.|.:||::|.|...|.:.:..|:|:||...  :.
Zfish   681 DSVQNEEEEEEEEEDDQILPGSTLFIKNLNFITSEETLQKTFSKCGVVKSCTISKKRDKAG--KL 743

  Fly   723 KSLGYGFIQFKKSSVAEHALKNLQLTHIDGNPVELKRSDRVLKTQDNDG---AQRRLASQKKQTG 784
            .|:||||:|:|....|:.|::.||...:|.:.:|:|.|:|.:|:    |   |:|:..:.:|||.
Zfish   744 LSMGYGFVQYKTPEAAQKAMRQLQHCTVDEHQLEVKISEREVKS----GVAQAKRKKQTARKQTT 804

  Fly   785 TKILVRNIPFQAQYREVRDIFKAFGELRSLRIPKKATTGEDAHRGFGFVDYMSKAEAKRAFDALS 849
            :|||||||||||..:|:|::|..||||:::|:|||...|  :||||||:|:::|.:||:||.||.
Zfish   805 SKILVRNIPFQATVKELRELFCTFGELKTVRLPKKGIGG--SHRGFGFIDFLTKQDAKKAFSALC 867

  Fly   850 ASTHLYGRRLVLEWSANDDNQDVEELRKRTAAKFDGSQAATAAKRSRKSFFDVEGSVQPNQDDDE 914
            .|||||||||||||:  |..:.|::||::||..|.     .|.|:.||:.. :||.::..:..|.
Zfish   868 HSTHLYGRRLVLEWA--DAEETVDDLRRKTAQHFH-----DAPKKKRKAEV-LEGILEQMEVGDG 924

  Fly   915 EEE 917
            :.|
Zfish   925 DGE 927

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3335	NP_648337.1	RRM1_RBM19	2..77	CDD:409980	41/74 (55%)
		PABP-1234	<245..>435	CDD:130689	69/196 (35%)
		RRM3_RBM19	362..440	CDD:409983	43/77 (56%)
		RRM4_RBM19	552..623	CDD:409984	37/70 (53%)
		PRK10819	<634..>680	CDD:236768	14/45 (31%)
		RRM5_RBM19_like	679..760	CDD:409757	31/80 (39%)
		RRM6_RBM19	785..864	CDD:409985	49/78 (63%)
rbm19	NP_944597.2	RRM1_RBM19	2..77	CDD:409980	41/74 (55%)
		RRM2_RMB19	290..361	CDD:409925	20/70 (29%)
		RRM3_RBM19	397..475	CDD:409983	43/77 (56%)
		RRM4_RBM19	585..656	CDD:409984	37/70 (53%)
		RRM5_RBM19_like	702..781	CDD:409757	31/80 (39%)
		RRM6_RBM19	805..882	CDD:409985	49/78 (63%)