DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3335 and Hrb27C

DIOPT Version :9

Sequence 1:	NP_648337.1	Gene:	CG3335 / 39119	FlyBaseID:	FBgn0036018	Length:	918	Species:	Drosophila melanogaster
Sequence 2:	NP_001162897.1	Gene:	Hrb27C / 33968	FlyBaseID:	FBgn0004838	Length:	421	Species:	Drosophila melanogaster

Alignment Length:	228	Identity:	54/228 - (23%)
Similarity:	93/228 - (40%)	Gaps:	56/228 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   663 EEDSRAEDADDEPEPNTTLFLRNLNFKTVQETVEKHFRHLGSIHTVEIAKRRDPENPREFKSLGY 727
            |||.|.:           ||:..|:::|.||.:.::|...|.|....:.|     |....:|.|:
  Fly     2 EEDERGK-----------LFVGGLSWETTQENLSRYFCRFGDIIDCVVMK-----NNESGRSRGF 50

  Fly   728 GFIQFKKSSVAEHALKNLQLTHIDGNPVELKRSDRVLKTQDNDGAQRRLASQKKQTGTKILVRNI 792
            ||:.|...:...|.|:|...| :||..::.|..:           .|.|...||..|.|:.:..:
  Fly    51 GFVTFADPTNVNHVLQNGPHT-LDGRTIDPKPCN-----------PRTLQKPKKGGGYKVFLGGL 103

  Fly   793 PFQAQYREVRDIFKAFGELRSLRI----PKKATTGEDAHRGFGFVDYMSKAEAKRAFDALSASTH 853
            |......::|..|..:|::..:.|    .||.:      |||||:          :|:..|:..|
  Fly   104 PSNVTETDLRTFFNRYGKVTEVVIMYDQEKKKS------RGFGFL----------SFEEESSVEH 152

  Fly   854 LYGRRLVLEWSANDDNQDVEELRKRTAAKFDGS 886
            :...|.:        |.:.:::..:.|...|||
  Fly   153 VTNERYI--------NLNGKQVEIKKAEPRDGS 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3335	NP_648337.1	RRM1_RBM19	2..77	CDD:241008
		RRM_SF	250..314	CDD:302621
		RRM3_RBM19	362..440	CDD:241011
		RRM4_RBM19	552..623	CDD:241013
		RRM	<638..845	CDD:223796	45/185 (24%)
		RRM5_RBM19_like	679..760	CDD:240764	23/80 (29%)
		RRM6_RBM19	785..864	CDD:241015	17/82 (21%)
Hrb27C	NP_001162897.1	RRM1_DAZAP1	8..89	CDD:241018	25/108 (23%)
Hrb27C	NP_001162897.1	RRM2_DAZAP1	94..173	CDD:240773	20/102 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464026
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930