Protein Alignment CG3335 and LOC1274962

DIOPT Version :10

• Sequence 1: NP_648337.1
• Gene: CG3335 / 39119
• FlyBaseID: FBgn0036018
• Length: 918
• Species: Drosophila melanogaster
• Sequence 2: XP_314164.5
• Gene: LOC1274962 / 1274962
• VectorBaseID: AGAMI1_006013
• Length: 898
• Species: Anopheles gambiae
• Alignment Length: 932
• Identity: 424/932 - (45%)
• Similarity: 584/932 - (62%)
• Gaps: 97/932 - (10%)

  Fly     1 MSRIIVKQLPKHITEDKLRQIFGAQGTITDLQLKYTPDGKFRQFCFVGYSTEEEAQSAIRHFDNT 65
            |||||||.:|....|.|:|..|...|.|||:|||||.:||||.|.|:|:.:||:|..||.||:|:
Mosquito    37 MSRIIVKNIPNGYDEAKVRSHFSTCGIITDVQLKYTSEGKFRNFGFIGFESEEQAAKAIAHFNNS 101

  Fly    66 CIQTSRVRVESCAALGSEDKPQSWSKYAKDSKKNLDKLKEKEREAAAKAKESEKKKKKDKVDKVD 130
            .|:||::.|.:|.||......:.|||:|:       |....|....||.:...|.|:|.|.....
Mosquito   102 YIRTSKITVAACVALSESKNLKVWSKHAQ-------KPATTETVEPAKDESKAKGKEKPKAQTAK 159

  Fly   131 QILSRHKDDPEFQEFLEAHDKS-RTLWGNDLGINKNRENEEEDDEEQEESRAARDDSGVDADAGD 194
            .:|.:::.||:|||||.||.:: :::|.|.|          |...|.|| :....||.||.:.
Mosquito   160 DVLGQYEKDPKFQEFLSAHKRAGKSVWDNLL----------EQSTEAEE-KLVSGDSAVDVEP-- 211

  Fly   195 EDGSGDEADEEEDTDKLAEKPISDLEYMKSLMATTSGEATAKKPKAKADKSNLELFTIKIHNVPY 259
               ..:..::|.|..|.|:||:                              :.||..|:||:|.
Mosquito   212 ---PAEAKEKEVDEKKAAKKPM------------------------------VSLFVAKVHNIPS 243

  Fly   260 NTKRQEVLKFFKPLKPYSVRLPSKVHGFCYVGFKTEKDMAKGMLKNKSFIKGKQVFFSDFTEKNK 324
            :||||::::|||.:||||||:|.|..||.|||||||.:::|.:|.||||:.||||...|||.::.
Mosquito   244 STKRQDLIRFFKTVKPYSVRIPPKQSGFAYVGFKTESELSKALLMNKSFLGGKQVKIFDFTARSA 308

  Fly   325 VTKASKSGQPLAPAAVDAGNAKWKHQQDSLSKEDDISESGRIFFRNLAYTTTEEDLRKLFEQFGP 389
            ...|.:.     |.|.....|||:.|:.:.|.| .|.|||::|||||||:..|.|:|.||||:||
Mosquito   309 AHAAQEK-----PEAKQGKQAKWERQKANASSE-AICESGKLFFRNLAYSVQESDIRTLFEQYGP 367

  Fly   390 VVEVNLPLDKLTRKIKGFGTVTYMMPEHALKAFNTLDGTDFHGRLLHLLPSKDIEKNPKEDLDEN 454
            |.||::|:|..|||:|||||||:|:||||:.|:|.|:||...||:.|:||:    |.|.::..::
Mosquito   368 VAEVDVPIDSNTRKLKGFGTVTFMIPEHAVTAYNELNGTFLQGRMFHILPA----KVPSDEAADD 428

  Fly   455 DASLSFKEKKALKLKKNAQKPIGWNTLFLGANAVAEILAKQFKTSKERILDTSDGGSSAAVRLAL 519
            |.: .:::||....||.||....|||||:|.|||||.:||::.|:||:||.:|:|.:||||||||
Mosquito   429 DTT-DYRKKKEQTQKKTAQSSHNWNTLFMGENAVAEAVAKKYGTTKEQILISSEGDTSAAVRLAL 492

  Fly   520 GETQVVIEMKRFLEEEGVRLDAFDEPAKKRSNTVILAKNLPAATEISEITPIFSRFGPIGRIVLP 584
            |||::|:||:.||:|.|:.||||.....|||:||||||||......:.:..:|:.||.:||:|||
Mosquito   493 GETELVLEMESFLKENGISLDAFSSTDAKRSSTVILAKNLAPGCTAAALRKLFAPFGLLGRVVLP 557

  Fly   585 PSGVTALIEYCDPLEARQAFKKLAYSKFKNAPLYLEWAPEQVFTKTLSGEPVIPKSEPKPKEEVK 649
            ||.|||:||:.||.|||:||||||||.|::.||||||||...||   ||          |.:.:.
Mosquito   558 PSAVTAVIEFLDPSEARKAFKKLAYSMFESLPLYLEWAPVGTFT---SG----------PSDPLS 609

  Fly   650 PEEKPIVNDAKPDEEDSRAEDA---DDEPEPNTTLFLRNLNFKTVQETVEKHFRHLGSIHTVEIA 711
            .|| |..:...|:...:..|:|   |.|||..||||::||:|.|.::.:.:.||.:|:||.|::.
Mosquito   610 TEE-PSKSSTAPENASNATEEATVDDTEPEEGTTLFIKNLSFTTNEDAIRERFRCVGAIHMVQVV 673

  Fly   712 KRRDPENPREFKSLGYGFIQFKKSSVAEHALKNLQLTHIDGNPVELKRSDRVLKTQDNDGAQRRL 776
            :..|.......:|.||||||||:...|::||||||...|||..|||.||||.|:|. .:||:||.
Mosquito   674 RSMDLSGNGRNESRGYGFIQFKRRQAADYALKNLQSVQIDGRTVELARSDRTLRTA-QEGAERRK 737

  Fly   777 ASQ--KKQTGTKILVRNIPFQAQYREVRDIFKAFGELRSLRIPKK-ATTGEDAHRGFGFVDYMSK 838
            .::  :||||.|||||||||||..:||||:||.||:::|||:||| |.:.:|.||||.||:|..:
Mosquito   738 GAKGAQKQTGCKILVRNIPFQASAKEVRDLFKPFGDIKSLRLPKKMAASADDTHRGFCFVEYDEE 802

  Fly   839 AEAKRAFDALSASTHLYGRRLVLEWSANDDNQDVEELRKRTAAKFDGSQAATAAKRSR--KSFFD 901
            ::||||||.|..|||||||||||||:|.|:  ||||||||||.:|:.....:..||:.  |....
Mosquito   803 SDAKRAFDTLGRSTHLYGRRLVLEWAAADN--DVEELRKRTAEQFNSRDGGSGGKRAATGKGTLA 865

  Fly   902 VEGSVQPNQ-------DDDEEE 916
            .|..:..:|       |||:::
Mosquito   866 TEEFISASQRKSGKNGDDDDDD 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3335	NP_648337.1	RRM1_RBM19	2..77	CDD:409980	39/74 (53%)
		PABP-1234	<245..>435	CDD:130689	99/189 (52%)
		RRM3_RBM19	362..440	CDD:409983	48/77 (62%)
		RRM4_RBM19	552..623	CDD:409984	43/70 (61%)
		PRK10819	<634..>680	CDD:236768	11/48 (23%)
		RRM5_RBM19_like	679..760	CDD:409757	37/80 (46%)
		RRM6_RBM19	785..864	CDD:409985	53/79 (67%)
LOC1274962	XP_314164.5	None