| Sequence 1: | NP_001287009.1 | Gene: | LanB2 / 39118 | FlyBaseID: | FBgn0267348 | Length: | 1639 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_002284.3 | Gene: | LAMC1 / 3915 | HGNCID: | 6492 | Length: | 1609 | Species: | Homo sapiens |
| Alignment Length: | 1621 | Identity: | 675/1621 - (41%) |
|---|---|---|---|
| Similarity: | 953/1621 - (58%) | Gaps: | 90/1621 - (5%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 56 ECYDPYGRPQKCLPEFINAAYQLQIESTNTCGEQNDNHFCIQT-MNQNHKNCEFC----KYNDHN 115
Fly 116 PSFLTDLHDPQSPTWWQSETMFEGIQHPNYVNLTLHLGKSYDITYVRILFRSPRPESFTIYKRTS 180
Fly 181 ESGPWIPYQFYSATCRDTYSLPDSRAIRKGEGEAHALCTSEYSDISPLRDGEIAFSTLEGRPSGI 245
Fly 246 NFERSGELQEWVTATDIRITLDRLNTFGDELFGDSQVLKSYFYAISDIAVGARCKCNGHASKCVP 310
Fly 311 STGMHGE-RTLVCECRHNTDGPDCDRCLPLYNDLKWKRSTSTEVNECKACNCNGLADKCFFDANL 374
Fly 375 FNRTGHGGHCLDCRENRDGPNCERCKENFY-MRDDGYCVNCACDPVGSRSLQCNSHGKCQCKPGV 438
Fly 439 TGDKCDRCDNNYYQFGPHGCQQCGCDSGGSHQNTPACDTETGICFCKENVEGRRCNECKPGFFNL 503
Fly 504 DKNNRFGCTPCFCYGHTSECMTAPGYSIVSVTSNFNKFKERWTAADLNQREVDIKYNQYSRSIGT 568
Fly 569 TAQGNEHVYFQAPDRFLGDQRASYNRDLKFKLQLVGQVANTGVSDVILEGAGSRISLPIFAQGNG 633
Fly 634 IPDQGVKEYTFRLHEHHDYQWQPSQSARGFLSILSNLTAIKIRATYSVQGEAILDDVELQTAHRG 698
Fly 699 AAGHPATWIEQCTCPEGYLGQFCESCAPGYRHSPARGGPFMPCIPCDCHGHADICDSETGRCICQ 763
Fly 764 HNTHGDNCDQCAKGFYGNALGGTPNDCKRCPCPNDGACLQI-NEDTVICTECPKGYFGSRCEQCS 827
Fly 828 DGFFGDPTGLLGEVQTCKSCDCNGNVDPNAVGNCNRTTGECLKCIHNTAGEHCDQCLSGHFGDPL 892
Fly 893 A-LPHGRCDRCSCYEAGTEQDEQSITRCDQVTGQCQCKPNVIGRDCGECQPGYFNIRSGNGCENC 956
Fly 957 LCDPVGSYNSTCDRYSGQCHCRPGVMGQRCDQCENYFYGFSSEGCKPCECDESGSKGFQCDQNGQ 1021
Fly 1022 CPCNDNVEGRRCDRCKENK-YDRH-RGCIDCPDCYNLVQDAADLHRAKLFNLSQTLDEIAR-TPV 1083
Fly 1084 TNDDEFEAKLKAVQEKVAVLAQDARDNSGDGGQTYAEVIDDLHKHLDSVREHLVSADKFQADANG 1148
Fly 1149 EIDRARQNYTILDQITENAKKELQQALDLLNDEGAQALARAKEKSVEFGQQSEQISDISREARAL 1213
Fly 1214 ADKLESEAQFDLKNAKDAKDAVEKAHQLA--------KSAIDLQLKIGTELRSEVGLELSHVKQS 1270
Fly 1271 L----GTVVQTSKEALRKANEVYDTALTLLNDVNRQTQPEIDISQLKKDAVAANERADELLKQIT 1331
Fly 1332 EL-SNSNGELFADFETEQELTEALLKRAEQQQLEDIELLERAKAAHDKATKAVEQGDNTLKEANN 1395
Fly 1396 TYEKLAGFQSDVQRSSESAEKALQTVPNIEKEIQNAESLISQAEEALDGANKNANEAKKNAQEAQ 1460
Fly 1461 LKYAEQASKDAELIRRKANETKVAARNLREEADQLNHRVK--LTEMDIFKLEESSTKDDNLVDDA 1523
Fly 1524 KRKVGQAKADTQEAQKQIEKANADLTA----IKDELENLKDINTGDLDRLENRLATVEGEINRV- 1583
Fly 1584 ------NLTGRIEKYREQRTIQKNLIDKYDAELRELKDEVQNIGLISKALPDSCFSRNRLE 1638 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| LanB2 | NP_001287009.1 | LamNT | 61..296 | CDD:214532 | 139/239 (58%) |
| EGF_Lam | 298..347 | CDD:238012 | 28/49 (57%) | ||
| Laminin_EGF | 359..414 | CDD:278482 | 27/55 (49%) | ||
| EGF_Lam | 414..458 | CDD:214543 | 24/43 (56%) | ||
| Laminin_EGF | 461..511 | CDD:278482 | 26/49 (53%) | ||
| LamB | 572..697 | CDD:214597 | 54/124 (44%) | ||
| TNFRSF | <721..848 | CDD:304602 | 59/127 (46%) | ||
| CRD2 | 724..771 | CDD:276900 | 22/46 (48%) | ||
| EGF_Lam | 743..791 | CDD:238012 | 22/47 (47%) | ||
| Laminin_EGF | 847..897 | CDD:278482 | 35/50 (70%) | ||
| Laminin_EGF | 902..953 | CDD:278482 | 24/50 (48%) | ||
| Laminin_EGF | 956..1004 | CDD:278482 | 24/47 (51%) | ||
| Laminin_EGF | 1004..1050 | CDD:278482 | 20/47 (43%) | ||
| V_Alix_like | 1122..1443 | CDD:187408 | 82/333 (25%) | ||
| Tar | 1139..1521 | CDD:223910 | 100/396 (25%) | ||
| BAR | 1308..1469 | CDD:299863 | 50/161 (31%) | ||
| vATP-synt_E | 1474..>1629 | CDD:304907 | 42/167 (25%) | ||
| LAMC1 | NP_002284.3 | Domain VI | 34..285 | 144/246 (59%) | |
| LamNT | 44..284 | CDD:214532 | 140/240 (58%) | ||
| EGF_Lam | 285..330 | CDD:238012 | 28/49 (57%) | ||
| Domain V | 286..509 | 122/230 (53%) | |||
| Laminin_EGF | 342..396 | CDD:278482 | 26/53 (49%) | ||
| Laminin_EGF | 398..445 | CDD:278482 | 26/46 (57%) | ||
| Laminin_EGF | 445..492 | CDD:278482 | 26/49 (53%) | ||
| Domain IV | 510..689 | 69/179 (39%) | |||
| LamB | 553..678 | CDD:214597 | 54/124 (44%) | ||
| Domain III | 690..1030 | 176/342 (51%) | |||
| EGF_Lam | 724..771 | CDD:238012 | 22/46 (48%) | ||
| EGF_Lam | 772..820 | CDD:238012 | 23/47 (49%) | ||
| Laminin_EGF | 828..875 | CDD:278482 | 33/46 (72%) | ||
| EGF_Lam | 883..933 | CDD:238012 | 25/52 (48%) | ||
| EGF_Lam | 935..980 | CDD:214543 | 21/44 (48%) | ||
| EGF_Lam | 982..1029 | CDD:238012 | 20/46 (43%) | ||
| Domain I/II | 1031..1609 | 161/616 (26%) | |||
| t_SNARE | 1072..1155 | CDD:197699 | 18/83 (22%) | ||
| MA | 1091..1302 | CDD:214599 | 46/227 (20%) | ||
| MCP_signal | 1123..1255 | CDD:304920 | 29/145 (20%) | ||
| V_Alix_like | 1180..>1336 | CDD:187408 | 41/170 (24%) | ||
| Laminin_I | 1287..1530 | CDD:283627 | 76/260 (29%) | ||
| SH3BP5 | 1361..1592 | CDD:283045 | 65/244 (27%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 289 | 1.000 | Domainoid score | I1574 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG1836 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H1724 | |
| Inparanoid | 1 | 1.050 | 1300 | 1.000 | Inparanoid score | I158 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG48740 | |
| OrthoDB | 1 | 1.010 | - | - | D156553at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002861 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41503 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_102334 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR10574 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2603 |
| SonicParanoid | 1 | 1.000 | - | - | X4311 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.910 | |||||