DRSC/TRiP Functional Genomics Resources

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Protein Alignment LanB2 and Megf9

DIOPT Version :9

Sequence 1:NP_001287009.1 Gene:LanB2 / 39118 FlyBaseID:FBgn0267348 Length:1639 Species:Drosophila melanogaster
Sequence 2:NP_001101410.1 Gene:Megf9 / 313270 RGDID:1308330 Length:599 Species:Rattus norvegicus


Alignment Length:470 Identity:112/470 - (23%)
Similarity:152/470 - (32%) Gaps:223/470 - (47%)


- Green bases have known domain annotations that are detailed below.


  Fly   359 CNCNGLADKCFFDANLFNRTGHGGHCLDCRENRDGPNCERCKENFYMRDD-GYCVNCACDPVGSR 422
            |||:.:..   .|....|:|  .|.| ||.....|.:|:.|||.||:... |.|:.|.|.|.|:.
  Rat   201 CNCSEVGS---LDVKRCNQT--TGQC-DCHVGYQGLHCDTCKEGFYLNHTVGLCLPCHCSPRGAV 259

  Fly   423 SLQCNSHGKCQCKPGVTGDKCDRCDNNYYQFGPHGCQQCGCDSGGSHQNTPACDTETGICF-CKE 486
            |:.|||.|.||||.||||..||:|.:.:|.||..||..|.|::     .:.:||..||.|. |:|
  Rat   260 SILCNSSGNCQCKLGVTGSMCDQCQDGHYGFGKTGCLPCQCNN-----RSDSCDVLTGACLNCQE 319

  Fly   487 NVEGRRCNECKPGFFNLDKNNRFGCTPCFCYGHTSECMTAPGYSIVSVTSNFNKFKERWTAADLN 551
            |.:|..|.|||.||:......|             ||:..|..::                    
  Rat   320 NTKGEHCEECKEGFYQSPDAAR-------------ECLRCPCSAV-------------------- 351

  Fly   552 QREVDIKYNQYSRSIGTTAQGNEHVYFQAPDRFLGDQRASYNRDLKFKLQLVGQVANTGVSDVIL 616
                             |:.||..:.|                                      
  Rat   352 -----------------TSTGNCTIEF-------------------------------------- 361

  Fly   617 EGAGSRISLPIFAQGNGIPDQGVKEYTFRLHEHHDYQWQPSQSARGFLSILSNLTAIKIRATYSV 681
                                 |..|.|                                      
  Rat   362 ---------------------GALEPT-------------------------------------- 367

  Fly   682 QGEAILDDVELQTAHRGAAGHPATWIEQC-TCPEGYLGQFCESCAPGYRHSPARGGPFMPCIPCD 745
                                        | .|.:||.||.|.:|..||.||.:      .|:.|:
  Rat   368 ----------------------------CDQCKDGYTGQNCNTCENGYYHSDS------ICLQCE 398

  Fly   746 CHGHAD------ICDSETGRCI-CQHNTHGDNCDQCAKGFYGNALGGTPNDCKR-CPCPNDGACL 802
            ||||.|      ||..|:|.|| |.|||.|..|::|.:|:.        .|.:| |         
  Rat   399 CHGHVDPIKTPKICKPESGECINCLHNTTGLWCEKCLEGYV--------RDLQRNC--------- 446

  Fly   803 QINEDTVICTECPKG 817
             |.::.::.|  |:|
  Rat   447 -IKQEVIVPT--PEG 458

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LanB2NP_001287009.1 LamNT 61..296 CDD:214532
EGF_Lam 298..347 CDD:238012
Laminin_EGF 359..414 CDD:278482 19/55 (35%)
EGF_Lam 414..458 CDD:214543 23/43 (53%)
Laminin_EGF 461..511 CDD:278482 18/50 (36%)
LamB 572..697 CDD:214597 6/124 (5%)
TNFRSF <721..848 CDD:304602 34/105 (32%)
CRD2 724..771 CDD:276900 23/53 (43%)
EGF_Lam 743..791 CDD:238012 21/54 (39%)
Laminin_EGF 847..897 CDD:278482
Laminin_EGF 902..953 CDD:278482
Laminin_EGF 956..1004 CDD:278482
Laminin_EGF 1004..1050 CDD:278482
V_Alix_like 1122..1443 CDD:187408
Tar 1139..1521 CDD:223910
BAR 1308..1469 CDD:299863
vATP-synt_E 1474..>1629 CDD:304907
Megf9NP_001101410.1 Baseplate_J <54..>175 CDD:294789
Laminin_EGF 201..244 CDD:278482 17/48 (35%)
Laminin_EGF 251..298 CDD:278482 25/46 (54%)
EGF_Lam 297..343 CDD:238012 18/63 (29%)
EGF_Lam 362..398 CDD:238012 16/107 (15%)
Laminin_EGF 397..441 CDD:278482 20/51 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10574
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
22.100

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