DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3306 and MORN1

DIOPT Version :9

Sequence 1:	NP_648335.1	Gene:	CG3306 / 39116	FlyBaseID:	FBgn0036016	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_079124.1	Gene:	MORN1 / 79906	HGNCID:	25852	Length:	497	Species:	Homo sapiens

Alignment Length:	278	Identity:	55/278 - (19%)
Similarity:	90/278 - (32%)	Gaps:	85/278 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 GVYIYPDGTC-YTGEFLNNRFHGKGTIQIPDSLGVTYQVTHHNGRLVSIDQVNFNDSLPVDFEMK 99
            |||:||:... |.||:...|.||.|.:...|  |..|:....:|.:..              |.:
Human    28 GVYVYPNSFFRYEGEWKAGRKHGHGKLLFKD--GSYYEGAFVDGEITG--------------EGR 76

  Fly   100 DHYTMSFKPWTYCTPEDRRFYQETKEPMDAVGPNKFQSKDGPNPLNLGRNIFDLGFGLLGNRGFM 164
            .|:.     |:..|...:....|.:      |....:.|.|      |....::..|:....||:
Human    77 RHWA-----WSGDTFSGQFVLGEPQ------GYGVMEYKAG------GCYEGEVSHGMREGHGFL 124

  Fly   165 LD-------------------TKTFSNQSIYLGCREARRWIRE--------NCAHGPLSKRHHKQ 202
            :|                   ...|.|...|.|     .|:|:        .||.|...|
Human   125 VDRDGQVYQGSFHDNKRHGPGQMLFQNGDKYDG-----DWVRDRRQGHGVLRCADGSTYK----- 179

  Fly   203 KLLARFAREIIRNNQENAGCSQREF---MTKIHPCKHSTSLDSFASERLHLASTTDSTTSEAQAM 264
               .::..::.......|.||...:   ....||.:.:|.:.....|.:.:|..:..:.: .|.:
Human   180 ---GQWHSDVFSGLGSMAHCSGVTYYGLWINGHPAEQATRIVILGPEVMEVAQGSPFSVN-VQLL 240

  Fly   265 GLRHEEFHGNWTRAKSES 282
                 :.||.  .|||||
Human   241 -----QDHGE--IAKSES 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3306	NP_648335.1	COG4642	<36..90	CDD:226989	16/54 (30%)
MORN1	NP_079124.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27
		MORN	39..61	CDD:280628	9/23 (39%)
		MORN 1	39..61		9/23 (39%)
		COG4642	59..191	CDD:226989	26/175 (15%)
		MORN 2	62..84		5/40 (13%)
		MORN 3	86..108		4/33 (12%)
		MORN 4	109..131		4/21 (19%)
		MORN 5	132..154		2/21 (10%)
		MORN	155..177	CDD:280628	7/26 (27%)
		MORN 6	155..177		7/26 (27%)
		MORN 7	178..200		4/29 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	393..425
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	468..497
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900