DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3306 and Jph3

DIOPT Version :9

Sequence 1:	NP_648335.1	Gene:	CG3306 / 39116	FlyBaseID:	FBgn0036016	Length:	288	Species:	Drosophila melanogaster
Sequence 2:	NP_065630.1	Gene:	Jph3 / 57340	MGIID:	1891497	Length:	744	Species:	Mus musculus

Alignment Length:	340	Identity:	64/340 - (18%)
Similarity:	100/340 - (29%)	Gaps:	153/340 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 TGSR----YVGPSDELGMQEMGVYIYPDGTCYTGEFLNNRFHGKGTIQIPDSLGVTYQVTHHNGR 79
            ||.:    |.| |...|.:.:|||.:|.|..|.|.:...:.||.|              ....|:
Mouse    31 TGPKGQGEYTG-SWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIG--------------LESKGK 80

  Fly    80 LVSIDQVNFNDSLPVDFEMKDHYTMSFKPWTY----CTPEDRRFYQETKEPMDAVGPNKFQSKDG 140
            .|                .|..:|..|| ..|    ||....::        :....|..|.
Mouse    81 WV----------------YKGEWTHGFK-GRYGVRECTGNGAKY--------EGTWSNGLQD--- 117

  Fly   141 PNPLNLGRNIFDLGFGLLGNRGFMLDTKTFSNQSIYLGCREARRW---------IRENCAHG--- 193
                         |:|          |:|:|:...|.|     :|         :|::..:|
Mouse   118 -------------GYG----------TETYSDGGTYQG-----QWVGGMRQGYGVRQSVPYGMAA 154

  Fly   194 ----PLS------KRHHKQ-----------------------KLLARFAREIIRNNQENAGCSQR 225
                ||.      :..|..                       .|:|....||:::.::  |..:|
Mouse   155 VIRSPLRTSINSLRSEHTNGAALHPDASPAVAGSPAVSRGGFVLVAHSDSEILKSKKK--GLFRR 217

  Fly   226 EFMTKIHPCKHSTSLDSFASERLHLA--------STTDSTTS---------EAQAM--------- 264
            ..::.: ..:.|.|..|.||:|...:        ||..||.|         ||:|.
Mouse   218 SLLSGL-KLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDID 281

  Fly   265 GLRHEEFHGNWTRAK 279
            ....|.:.|.|...|
Mouse   282 ATTTETYVGEWKNDK 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3306	NP_648335.1	COG4642	<36..90	CDD:226989	12/53 (23%)
Jph3	NP_065630.1	PLN03185	5..>144	CDD:215619	35/183 (19%)
		MORN 1	15..37		2/5 (40%)
		MORN 2	39..60		9/21 (43%)
		MORN 3	61..82		6/34 (18%)
		MORN 4	83..105		7/22 (32%)
		MORN 5	107..129		7/55 (13%)
		MORN 6	130..152		4/26 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	230..252		5/21 (24%)
		PLN03185	287..>342	CDD:215619	3/10 (30%)
		MORN 7	288..310		3/9 (33%)
		MORN	311..333	CDD:308220
		MORN 8	311..333
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	451..603
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	624..677
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4642
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900