| Sequence 1: | NP_729510.1 | Gene: | CG42673 / 39111 | FlyBaseID: | FBgn0261555 | Length: | 904 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_005447.1 | Gene: | MAPK8IP1 / 9479 | HGNCID: | 6882 | Length: | 711 | Species: | Homo sapiens |
| Alignment Length: | 364 | Identity: | 73/364 - (20%) |
|---|---|---|---|
| Similarity: | 103/364 - (28%) | Gaps: | 142/364 - (39%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 542 AGLTSANIGMAPQQSQLQM----LLQATSNNNNLATINQQISNLGSINQQLTSLSHQLSGLNQQS 602
Fly 603 QHLQNLQQQQQQQQQQQQQQTQAAPTAATPPPAAGGSSPYPSMSALQSISNQLQQQQQQQQQDAL 667
Fly 668 SKDLFQVNQELLNRLQALNLNANPGQSQPTPSATAHNSFFYVNPLSCTPATPNNNAGG-----AG 727
Fly 728 GFNFLTSPAATGTLTPSPLGTMNRNSFAGSSSLNEDIRLSIEQNLNNLEEQLKAA--VSNGNLAG 790
Fly 791 LACGGSTSTRDTSRSSSTLDSPSSPRLRSSNNNISPGSSNGNQNHNNNSNSNSSSSRETRFNTVL 855
Fly 856 LRVTDE---AGHQRKLSATPSFITRSTSEKVPNRSQMMS 891 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG42673 | NP_729510.1 | PH-like | <352..386 | CDD:473070 | |
| MAPK8IP1 | NP_005447.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..27 | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 78..371 | 69/359 (19%) | |||
| JNK-binding domain (JBD) | 127..285 | 50/239 (21%) | |||
| Minimal inhibitory domain (MID) | 157..176 | 6/44 (14%) | |||
| Interaction with MAP3K7. /evidence=ECO:0000269|PubMed:17709393 | 283..471 | 8/31 (26%) | |||
| D-box 1 | 353..360 | ||||
| D-box 2 | 364..372 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 429..451 | ||||
| Interaction with VRK2. /evidence=ECO:0000269|PubMed:18286207 | 471..660 | ||||
| SH3_JIP1 | 492..546 | CDD:212876 | |||
| PTB_JIP | 563..711 | CDD:269923 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||