Protein Alignment CG42673 and numbl

DIOPT Version :10

• Sequence 1: NP_729510.1
• Gene: CG42673 / 39111
• FlyBaseID: FBgn0261555
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: XP_005173435.1
• Gene: numbl / 497616
• ZFINID: ZDB-GENE-051113-340
• Length: 640
• Species: Danio rerio
• Alignment Length: 590
• Identity: 125/590 - (21%)
• Similarity: 195/590 - (33%)
• Gaps: 154/590 - (26%)

  Fly   324 GLAIADCDNLCNNRTKDAI-------SCGCATSDPESQAMRIVRTVGQAFE-VCHKFNLHKNSLE 380
            ||.:.|      ::|||.|       ...||......:|...:...|.... :||.|...|:|.|
Zfish   105 GLRVVD------DKTKDLIVDQTIEKVSFCAPDRNYDKAFSYICRDGTTRRWMCHCFMALKDSGE 163

  Fly   381 PNDERSDISSSELLDVEQISEQQ----LSEDGERGGGDNETPKKEHLAITPDLNHTQPQRPNHLD 441
            ........:.:..|:.:|..|::    .|.|..|.....|...:...|         .|:.:..|
Zfish   164 RLSHAVGCAFAACLERKQRREKECGVTASFDASRTSFVREGSFRVSSA---------AQQSDRED 219

  Fly   442 IMPSHSSLRKSNSLLCDVDDKSPGSPSSPRSEIT--QLKDQLEAQALQTRQALGQLMLVREQLIS 504
            ||......:|.   :|.:....||:.|.|....:  :..:.....|:..|.|      ..|||:.
Zfish   220 IMKQIQDKKKE---MCGISALPPGNASPPEGAGSPGERAEPGGPHAIPRRHA------PIEQLVR 275

  Fly   505 ETNARIEAQARTQQLLQQN----RELLEHLASLGAYNEQQTAGLTSANIGMAPQQSQLQMLLQAT 565
            :.:.|     ...||.|:|    |:|...|..|.:..:::|...|...:    .:..|.:..:|.
Zfish   276 QGSFR-----GFPQLSQKNSPFKRQLSLRLNDLPSTLQRKTDFQTKNPV----PEMDLTVAGEAD 331

  Fly   566 SNNNNLATINQQI------------SNLGSIN------------QQLTSLSHQLSGLNQ------ 600
            |.|...:.||...            :|...|:            .|.|:|..|:....|
Zfish   332 SINALCSQINSSFTKPSEDLCAKTTNNCLPISCAPPAIPPPPAPPQATNLWVQIEPPVQSSPPIP 396

  Fly   601 QSQHLQNLQQQQQQQQQ-----QQQQQTQAA----PTAATPP----PAAGGSSP---YPSMSALQ 649
            |..|.:...:.::..::     :.||||...    ||...||    |.|.||.|   .|...|..
Zfish   397 QGGHKRTPSEAERWLEEVAKAVKSQQQTPPTLPPPPTQQPPPVPTMPIAPGSLPTSMQPFPMAFD 461

  Fly   650 SISNQLQQQQQQQQQDALSKDLFQVNQELLNRLQALNLNANPGQSQP----TPSATAHNSFFYVN 710
            .....:....||..|.|     |...|..:..|  .|....|..|.|    |||....|.|
Zfish   462 VTPAPVSMFTQQPLQPA-----FVPMQPYMPTL--ANSMTYPNASVPVVGITPSQMVANVF---- 515

  Fly   711 PLSCTPA-------------TPNNNAGGAGGFNFLTSPAATGTLTPSPLGTMN---RNSFAGSSS 759
               |:.|             ......||:....|.|.|....|.|.:...|:|   :|||..:::
Zfish   516 ---CSAAGTGGGVAIGVGMGPKTGTLGGSQHSAFPTLPGGLPTTTFASPPTINGHPQNSFPSTTT 577

  Fly   760 LNEDIRLSIEQNLNNLEEQLKAAVSNGNLAGLACGGSTSTRDTSRSS------STLDSPSSPRLR 818
                   |:.||        ..||..|  :|........|.::..:.      :.|:|.|.|:.:
Zfish   578 -------SVTQN--------GTAVKGG--SGWPMENPNPTINSKEAEHFDAKWAALESKSQPKAQ 625

  Fly   819 SSNNN 823
            :..:|
Zfish   626 NPFSN 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42673	NP_729510.1	PH-like	<352..386	CDD:473070	8/34 (24%)
numbl	XP_005173435.1	PTB_Numb	45..179	CDD:241298	18/79 (23%)
		NumbF	260..344	CDD:461874	23/98 (23%)