Protein Alignment CG42673 and ced-6

DIOPT Version :10

• Sequence 1: NP_729510.1
• Gene: CG42673 / 39111
• FlyBaseID: FBgn0261555
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_001246225.1
• Gene: ced-6 / 35971
• FlyBaseID: FBgn0029092
• Length: 533
• Species: Drosophila melanogaster
• Alignment Length: 606
• Identity: 115/606 - (18%)
• Similarity: 195/606 - (32%)
• Gaps: 218/606 - (35%)

  Fly   180 KEQPVAKSSHKASNSTSNAAQSNGDVLKARLKFKRLPGDHYEASPEALRRAHLLHQRSEQRHQLQ 244
            |..|.....::.:||...:..|......|:|||..                   .|.|.::.|..
  Fly    10 KTAPTTTMPYQPANSGGTSGGSKAAAKMAQLKFWN-------------------KQNSSKQQQQD 55

  Fly   245 RRKSLSDQQSSSSLSSGGGGGGNANGSIMLERPKTDKPRKKLSFREPIIAG-------------- 295
            :.|..:|   ..:.:||||.|.|:||....| .|..| |..|...|.:|:|
  Fly    56 KDKDAAD---GGNNTSGGGTGSNSNGDAKSE-AKNGK-RNWLHTPEQLISGHAVYLVKFFGNLSV 115

  Fly   296 DQ----------ILPLILSEQRQARQRRRSSPLERSRV-----GLAIADCD-------------N 332
            ||          |..|..::|.:..:.......::..:     |:||.:..             :
  Fly   116 DQPKGIEVVKEAIRKLQFAQQMKKAETGTQEKFKKLEITISIKGVAIQEPRTHKILHQFPLYNIS 180

  Fly   333 LCNN---------------RTKDAISCGCATSDPESQ---------------------------A 355
            .|.:               :|:|.       |||.|.                           |
  Fly   181 YCADEKGVKKFFSFIAKTVKTQDG-------SDPTSNGHANGNGDGSAKVEESHECFVFISNKLA 238

  Fly   356 MRIVRTVGQAFEVCHKFNLHKNSLEPNDERSDISSSE-----LLDVEQISEQQLSEDGERGGGDN 415
            ..|..|:||||::.::      ....:.|::::|.::     |.....:.:::|.|...:
  Fly   239 SDITLTIGQAFDLAYR------KYMDSTEKTNLSKAQQQINHLQQTVNVYKERLREVSAK----- 292

  Fly   416 ETPKKEHLAITPDLN--------HTQPQRPNHLDIMPSHSSLRK--SNSLLCDVDDKS----PGS 466
             .||.|..|:..:|.        .|:||  |.:::.....|..|  .:.||.|.:..:    ..|
  Fly   293 -LPKAELDALLFNLGIKDILEAPTTEPQ--NGIEVASEALSNGKLDDDKLLIDTNSTTASTHSAS 354

  Fly   467 PSS------PRSEITQLKDQLEAQALQTRQALGQLMLVREQLISETNARIEAQA-RTQQLLQQNR 524
            |||      ||:   .|..|:........|.:.:|:     |.|::::..:.:| .||::....|
  Fly   355 PSSFLPIVPPRN---NLSSQISIGGKSNSQKMDELL-----LNSDSDSDFDPRADETQEIGGTGR 411

  Fly   525 ELLEHLASLGAYNEQQTAGLTSANIGMAPQQSQLQMLLQATSNNNNLATINQQISNLGSINQQLT 589
            ..:.::                  .|..|..|..|.|.   ||||:....|...|.|.:.|....
  Fly   412 SAISNM------------------FGFEPANSFGQHLF---SNNNDHKLQNNNSSLLITSNNNSI 455

  Fly   590 SLSHQLSGLNQQSQHLQNLQQQQQQQQQQQQQQTQAAPTAATPPPAAGGSSPYPSMSALQSISNQ 654
            :.|...|.||                              .|||..|    |.|.::|.:.:::.
  Fly   456 NSSGFSSELN------------------------------ITPPLLA----PPPKIAAPRRLNSV 486

  Fly   655 LQQQQQQQQQDALSKDLFQVN 675
            ..........|....|.|::|
  Fly   487 TTGNGLNGNTDLFGSDPFELN 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42673	NP_729510.1	PH-like	<352..386	CDD:473070	9/60 (15%)
ced-6	NP_001246225.1	PTB_CED-6	92..261	CDD:269971	26/181 (14%)