Protein Alignment CG42673 and numb

DIOPT Version :10

• Sequence 1: NP_729510.1
• Gene: CG42673 / 39111
• FlyBaseID: FBgn0261555
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_523523.2
• Gene: numb / 34263
• FlyBaseID: FBgn0002973
• Length: 556
• Species: Drosophila melanogaster
• Alignment Length: 688
• Identity: 127/688 - (18%)
• Similarity: 184/688 - (26%)
• Gaps: 304/688 - (44%)

  Fly   203 GDV---LKARLKFKRLPGDHYEASPEALRRAHLLHQRSEQRHQLQRRKSLSDQQSSSSLSSGGGG 264
            |||   ..|..:|.:       .||:.:.|.     |...|...:|||.
  Fly    22 GDVKNGKSASFRFSK-------KSPKKMDRL-----RRSFRDSFRRRKD---------------- 58

  Fly   265 GGNANGSIMLERPKTDKPRKKLSFREPIIA-------------------GDQILPLILSEQRQAR 310
                      ..|::.||.:..:..|.:.:                   |.|:....|...||:|
  Fly    59 ----------RVPESSKPHQWQADEEAVRSATCSFSVKYLGCVEVFESRGMQVCEEALKVLRQSR 113

  Fly   311 QRRRSSPLERSRVGLAIADCDN---------------------------LCNNRTKDAISC---- 344
            :|.....|..|..||.:.|.:.                           :|.:.|.....|
  Fly   114 RRPVRGLLHVSGDGLRVVDDETKGLIVDQTIEKVSFCAPDRNHERGFSYICRDGTTRRWMCHGFL 178

  Fly   345 GCATSDPESQAMRIVRTVGQAFEVCHKFNLHKNSLEPNDERS---------DISSSELLDVEQIS 400
            .|..|     ..|:...||.||.||         ||....|.         |..:|.........
  Fly   179 ACKDS-----GERLSHAVGCAFAVC---------LERKQRRDKECGVTMTFDTKNSTFTRTGSFR 229

  Fly   401 EQQLSE--------DGERG--GGDNETPKKEHLAITPDLNHTQPQRPNHL-DIMPSHSSLRKS-- 452
            :|.|:|        ..||.  |..:..|......:.| .|....:||:.. :::...||.|.|
  Fly   230 QQTLTERLAMATVGTNERSVDGPGSAMPGPPAATVKP-FNPFAIERPHATPNMLERQSSFRLSTI 293

  Fly   453 --------------NSLLCDVDDK------SPGSPS-------SPRSEITQLK----DQLEAQAL 486
                          |.|..:.|.:      :.|:|.       ||.:|::..|    |.|.|.|:
  Fly   294 GSQSPFKRQMSLRINDLPSNADRQRAFLTAAAGNPMQTPLRSVSPIAEVSPAKSAGADPLSAAAV 358

  Fly   487 QTRQALGQLMLVREQLISETNARIEAQARTQQLLQQNRELLEHLASLGAYNEQQTAGLTSANIGM 551
            .....        .||..|.:..:....:|..||....:|
  Fly   359 AADSV--------SQLCQELSQGLSLLTQTDALLAAGEDL------------------------- 390

  Fly   552 APQQSQLQMLLQATSNNNNLATINQQISNLGSINQQLTSLSHQLSGLNQQSQHLQNLQQQQQQQQ 616
                           |.||..:|||.|                 ....:|.||:
  Fly   391 ---------------NFNNNRSINQNI-----------------IAAEKQVQHV----------- 412

  Fly   617 QQQQQQTQAAPTAATPPPAAGGSSPYPSMSALQSISNQLQQQQQQQQQDALSKDLFQVNQELLNR 681
                 .:.|.|||...|..|   |..|:...|.|            |..:.|:...:.:.||.|.
  Fly   413 -----HSYAPPTAQVTPRVA---STTPTYQTLHS------------QSPSRSEQSIETSTELPNA 457

  Fly   682 LQAL---------------NLNANPGQSQPTPSATAHNSFFYVNPLSCTPATPNNNAGGAGG--- 728
            .|.|               ...||.|::|...|.|                   ..|.|.||
  Fly   458 EQWLGHVVRSTSPAAPKRPTYLANVGRAQTLASGT-------------------GAAVGGGGPDD 503

  Fly   729 ---FNFLTSPAATGTLTP---------SPLGTMNRNSF 754
               ..::.:.||...|:|         |||...:.|.|
  Fly   504 PFDAEWVANVAAAKQLSPDLPIPSTARSPLARHSTNPF 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42673	NP_729510.1	PH-like	<352..386	CDD:473070	9/33 (27%)
numb	NP_523523.2	PTB_Numb	67..201	CDD:241298	26/147 (18%)
		NumbF	269..374	CDD:461874	22/112 (20%)