Protein Alignment CG42673 and Dab1

DIOPT Version :10

• Sequence 1: NP_729510.1
• Gene: CG42673 / 39111
• FlyBaseID: FBgn0261555
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: XP_017448664.1
• Gene: Dab1 / 266729
• RGDID: 628770
• Length: 588
• Species: Rattus norvegicus
• Alignment Length: 645
• Identity: 120/645 - (18%)
• Similarity: 200/645 - (31%)
• Gaps: 253/645 - (39%)

  Fly   367 EVCHKFNLHKNSLEPNDERSDIS------------SSELLDVEQISE---QQLSED--------- 407
            :|..|.:..|:|.:...:||:.:            .::|:.::::|.   .:|.:|
  Rat     8 QVAVKTSAKKDSRKKGQDRSEATLIKRFKGEGVRYKAKLIGIDEVSAARGDKLCQDSMMKLKGVV 72

  Fly   408 -GERGGGDNETPKKEHLAI-----------TPDLNHTQPQRPNHLDIMPSHSSLRKSNSLLCDVD 460
             |.|..|:::  :|..|.|           |..|.|              |.::.:.:.:..|:.
  Rat    73 AGARSKGEHK--QKIFLTISFGGIKIFDEKTGALQH--------------HHAVHEISYIAKDIT 121

  Fly   461 DKSP-----GSPSSPRSEITQLKDQLEAQALQTRQALGQLML-VRE--QLISETNARIEAQARTQ 517
            |...     |...:.|           ..|::|.||...::| :|:  |||.|...|.|.:.:.|
  Rat   122 DHRAFGYVCGKEGNHR-----------FVAIKTAQAAEPVILDLRDLFQLIYELKQREELEKKAQ 175

  Fly   518 Q-----------LLQQNRE--LLEHLASLGAYNEQQTAGLTSANIGMAPQQSQLQMLL-----QA 564
            :           :|:::.|  :.:::. ..|.:|......|..||...|...:.:.:.     |.
  Rat   176 KDKQCEQAVYQTILEEDVEDPVYQYIV-FEAGHEPIRDPETEENIYQVPTSQKKEGVYDVPKSQP 239

  Fly   565 TSNNNNL---------ATINQQIS----NLGSINQQLTSL------------------------- 591
            .||:..|         ||.|..:|    .|....:.:|.|
  Rat   240 VSNSQPLEDFEARFAAATPNGNLSMDFDELLEATKAVTQLELFGDMSTPPDITSPPTPATPGDAF 304

  Fly   592 ----SHQL------------------SGLNQQSQHLQNLQQQQQQQQQQ-----QQQQTQAAPTA 629
                |..|                  ||.......|.:...||...|||     |....|..|.|
  Rat   305 LPAPSQTLPGSADVFGSMSFGTAAVPSGYVAMGAVLPSFWGQQPLVQQQIAMGAQPPVAQVIPGA 369

  Fly   630 ------------AT--PPPAAGGS------------SPYPS------MSALQSISNQLQQQQQQQ 662
                        ||  |.|...|.            .|.|:      ::.|.::.......:...
  Rat   370 QPIAWGQPGLFPATQQPWPTVAGQFPPAAFMPTQTVMPLPAAMFQGPLTPLATVPGTNDSARSSP 434

  Fly   663 QQDALSKDLFQVNQELLNRLQALNLNANPGQSQPTPSAT----AHNSFFY--------------- 708
            |.|   |...::.:|:....|.......|.:....||.|    |.:|:|.
  Rat   435 QSD---KPRQKMGKEMFKDFQMAQPPPVPSRKPDQPSLTCTSEAFSSYFNKVGVAQDTDDCDDFD 496

  Fly   709 VNPLSCTPATPNNNAGGAGGFNFLTSPAATGTLTPSPLGTMNRNSFAGSSSLN-------EDIRL 766
            ::.|:.||.|.             |:|:.....||:|     |.|....||.:       :||..
  Rat   497 ISQLNLTPVTS-------------TTPSTNSPPTPAP-----RQSSPSKSSASHVSDPTADDIFE 543

  Fly   767 SIEQNLNNLEEQLKAAVSNGNLAGLACGGSTSTRDTSRSSSTLDSPSSPRLRSSNNNISP 826
            ...::.:..|||                   ...|.|::|||.|....|....|.:||||
  Rat   544 EGFESPSKSEEQ-------------------EAPDGSQASSTSDPFGEPSGEPSGDNISP 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42673	NP_729510.1	PH-like	<352..386	CDD:473070	4/18 (22%)
Dab1	XP_017448664.1	PTB_Dab	25..174	CDD:269926	32/175 (18%)
		PHA03247	<287..580	CDD:223021	60/332 (18%)