Protein Alignment CG42673 and Dab1

DIOPT Version :10

• Sequence 1: NP_729510.1
• Gene: CG42673 / 39111
• FlyBaseID: FBgn0261555
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_001355978.1
• Gene: Dab1 / 13131
• MGIID: 108554
• Length: 588
• Species: Mus musculus
• Alignment Length: 653
• Identity: 120/653 - (18%)
• Similarity: 201/653 - (30%)
• Gaps: 269/653 - (41%)

  Fly   367 EVCHKFNLHKNSLEPNDERSDIS------------SSELLDVEQISE---QQLSED--------- 407
            :|..|.:..|:|.:...:||:.:            .::|:.::::|.   .:|.:|
Mouse     8 QVAVKTSAKKDSRKKGQDRSEATLIKRFKGEGVRYKAKLIGIDEVSAARGDKLCQDSMMKLKGVV 72

  Fly   408 -GERGGGDNETPKKEHLAI-----------TPDLNHTQPQRPNHLDIMPSHSSLRKSNSLLCDVD 460
             |.|..|:::  :|..|.|           |..|.|              |.::.:.:.:..|:.
Mouse    73 AGARSKGEHK--QKIFLTISFGGIKIFDEKTGALQH--------------HHAVHEISYIAKDIT 121

  Fly   461 DKSP-----GSPSSPRSEITQLKDQLEAQALQTRQALGQLML-VRE--QLISETNARIEAQARTQ 517
            |...     |...:.|           ..|::|.||...::| :|:  |||.|...|.|.:.:.|
Mouse   122 DHRAFGYVCGKEGNHR-----------FVAIKTAQAAEPVILDLRDLFQLIYELKQREELEKKAQ 175

  Fly   518 Q-----------LLQQNRE--LLEHLASLGAYNEQQTAGLTSANIGMAPQQSQLQMLL-----QA 564
            :           :|:::.|  :.:::. ..|.:|......|..||...|...:.:.:.     |.
Mouse   176 KDKQCEQAVYQTILEEDVEDPVYQYIV-FEAGHEPIRDPETEENIYQVPTSQKKEGVYDVPKSQP 239

  Fly   565 TSNNNNL---------ATINQQIS----NLGSINQQLTSLSHQLSG------------------- 597
            .||:..|         ||.|:.:|    .|....:.:|.|  :|.|
Mouse   240 VSNSQPLEDFDSRFAAATPNRNLSMDFDELLEATKAVTQL--ELFGDMSTPPDITSPPTPATPGD 302

  Fly   598 --LNQQSQHLQNL------------------------------QQQQQQQQQQQQQQ-------- 622
              |...||.|...                              ||...|||.....|
Mouse   303 AFLPSSSQTLPGSADVFGSMSFGTAAVPSGYVAMGAVLPSFWGQQPLVQQQIAMGAQPPVAQVIP 367

  Fly   623 ----------------TQAAPTAATP-PPAA----------------GGSSPYPSMSALQSISNQ 654
                            .||.||.|.. ||||                |..:|..::......:..
Mouse   368 GAQPIAWGQPGLFPATQQAWPTVAGQFPPAAFMPTQTVMPLAAAMFQGPLTPLATVPGTNDSARS 432

  Fly   655 LQQQQQQQQQDALSKDLFQVNQELLNRLQALNLNANPGQSQPTPSAT----AHNSFFY------- 708
            ..|..:.:|         ::.:|.....|.:.....|.:....||.|    |.:|:|.
Mouse   433 SPQSDKPRQ---------KMGKESFKDFQMVQPPPVPSRKPDQPSLTCTSEAFSSYFNKVGVAQD 488

  Fly   709 --------VNPLSCTPATPNNNAGGAGGFNFLTSPAATGTLTPSPLGTMNRNSFAGSSSLN---- 761
                    ::.|:.||.|.             |:|:.....||:|     |.|....||.:
Mouse   489 TDDCDDFDISQLNLTPVTS-------------TTPSTNSPPTPAP-----RQSSPSKSSASHVSD 535

  Fly   762 ---EDIRLSIEQNLNNLEEQLKAAVSNGNLAGLACGGSTSTRDTSRSSSTLDSPSSPRLRSSNNN 823
               :||.....::.:..|||                   ...|.|::|||.|....|....|.:|
Mouse   536 PTADDIFEEGFESPSKSEEQ-------------------EAPDGSQASSTSDPFGEPSGEPSGDN 581

  Fly   824 ISP 826
            |||
Mouse   582 ISP 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42673	NP_729510.1	PH-like	<352..386	CDD:473070	4/18 (22%)
Dab1	NP_001355978.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		4/17 (24%)
		PTB_Dab	25..174	CDD:269926	32/175 (18%)
		PRK07764	<288..469	CDD:236090	27/189 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	420..444		2/32 (6%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	451..470		4/18 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	502..588		29/120 (24%)