DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir67a and Ir7c

DIOPT Version :9

Sequence 1:	NP_648329.3	Gene:	Ir67a / 39110	FlyBaseID:	FBgn0036010	Length:	584	Species:	Drosophila melanogaster
Sequence 2:	NP_001245572.1	Gene:	Ir7c / 31692	FlyBaseID:	FBgn0029966	Length:	625	Species:	Drosophila melanogaster

Alignment Length:	601	Identity:	116/601 - (19%)
Similarity:	214/601 - (35%)	Gaps:	157/601 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 SGLERFPWPVFSFNEQMDFYVR---------GKYNSEMLVLIWQTGNSDWDLDLWQALDRSLLNM 101
            |||...|..:: |.:.:..|.|         ..|......|:..||..|..::..:.:.|.||||
  Fly    85 SGLTGRPIAIW-FLDSLRSYFRLEMYLNQLGSPYKRNGFFLVIYTGLEDQPMESLKIMFRRLLNM 148

  Fly   102 RKVRVLLLRKWEKIPTADVAATAEHLLFLHVAVIGQGN-RIYRLQPYAP---QSWLQV------- 155
                                    ::|.::|.:...|. .:|...||.|   ||.|.|
  Fly   149 ------------------------YVLNVNVFLQRDGTVHLYTYYPYGPHHCQSSLPVYYTAFQD 189

  Fly   156 --DP-----IESPIF-IKIRNYFGRYIVTLPDQFPPRSIVYRNPKTDEIQ----MTGYVYKFLLE 208
              .|     :..|:| .|:.|..|..:|....:..|..|:..:|||...:    :.|.:::.|.|
  Fly   190 LAAPANGFGLTKPLFPRKLTNMHGCEMVVATFEHRPYVIIEDDPKTPGGRSIHGIEGLIFRSLAE 254

  Fly   209 FIRIYNFTFRW--QRPIVQGERM---NLILLRNMTLNGTINLAISLCGFETPSELGVFSDVYDME 268
            .:   |||.:.  |:...:||.:   |...:..|.::|.:||.. :|            .:|...
  Fly   255 RM---NFTIKLVEQKDKNRGEILPDGNFTGILKMMVDGEVNLTF-VC------------FMYSKA 303

  Fly   269 EWYIMVPRAQEISIADVYVVMVSGNF-----------------LIVLIIFYFIFTILDTCFGPLL 316
            ...:|:|.....|...|.||...|:.                 ::|.:||.|:...|      |.
  Fly   304 RSDLMLPSTSYTSFPIVLVVPSGGSISPMGRLTRPFRYIIWSCILVSLIFGFVLICL------LK 362

  Fly   317 LKERVDWSNLMLNERMISGIMGQSFNMSARNTISSKVTNATLFLL------GLVLSTLYAAHLKT 375
            :.......||:|..|.....||...::.....:.:...|...::|      .|:|...|...|..
  Fly   363 ITALPGLRNLVLGRRNRLPFMGMWASLLGGLALYNPQRNFARYILVMWLLQTLILRAAYTGQLYL 427

  Fly   376 LLTK-------RPTSQQISNFKQLRDSPV--TVFFEE--AERFYLKHAWDRPIRYIKDQLN---- 425
            ||..       :..|:.::...:.|..|.  |:|.:.  ...|:...:.:..:..::|:.:
  Fly   428 LLQDVEMRSPIKSLSEVLAKDYEFRILPALRTIFKDSMPTTNFHAVLSLEESLYRLRDEDDPGIT 492

  Fly   426 ---FRETIEYNALRMGLNRSNAFSALTSEWMIVAKRQELFKQPIFTVQPELRVIQTSVLLSLVMQ 487
               .:.|:.....|.|.|:.:    ||           :...|:.|..           |:..|:
  Fly   493 VALLQPTVNQFDFRSGPNKRH----LT-----------VLPDPLMTAP-----------LTFYMR 531

  Fly   488 SNSIYEDHINDLIHRVQSAGIVEYWKHQTLREMITMGMISQKDPFPYVAFREFKVGDLFWIWLLW 552
            .:|.::..|:.||..:.|:|||..::...:..:..:......:|.|...:|      |..|::..
  Fly   532 PHSYFKRRIDRLIMAMMSSGIVARYRKMYMDRIKRVSKRRNLEPKPLSIWR------LSGIFVCC 590

  Fly   553 VSFLFMSFVIFLCELL 568
            .....::.::|:.|:|
  Fly   591 AGLYLVALIVFILEIL 606

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir67a	NP_648329.3	None
Ir7c	NP_001245572.1	Lig_chan-Glu_bd	225..287	CDD:214911	16/64 (25%)
Ir7c	NP_001245572.1	Lig_chan	343..593	CDD:278489	50/287 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010