Protein Alignment CG3408 and Lrrc59

DIOPT Version :10

• Sequence 1: NP_648328.1
• Gene: CG3408 / 39107
• FlyBaseID: FBgn0036008
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_598568.1
• Gene: Lrrc59 / 98238
• MGIID: 2138133
• Length: 307
• Species: Mus musculus
• Alignment Length: 344
• Identity: 111/344 - (32%)
• Similarity: 162/344 - (47%)
• Gaps: 80/344 - (23%)

  Fly     1 MPKPGDKAKVKVNVKERVVDETCDLSLSELSEIPVREIASFKRVTVLDLSSNRLVNLGKNFSILT 65
            |.|.|.|..   |:::::.....|||||:|:|:||:|:|:..:.||||||.|:|..|..:|..||
Mouse     1 MTKAGSKGG---NLRDKLDGNELDLSLSDLNEVPVKELAALPKATVLDLSCNKLSTLPSDFCGLT 62

  Fly    66 RLVRLDLSKNQIKFLPEDFGQLEQLRHLDLYNNCLEHLPISFGQLRRLRYLDLKGNPLTPAWEKI 130
            .||:||||||:::.||.|||:|..|:||||.||.|..||:||.||:.|::||||.|||.|...|:
Mouse    63 HLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNRLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKV 127

  Fly   131 VGCCSTQKDCQQAAKNTVSICANYKPEFI-------ERERLAAQESQKMAGAGDSSANAVQTNGG 188
            .|.|..:|.|:|        |||...:.:       ||||....|.::
Mouse   128 AGDCLDEKQCKQ--------CANKVLQHMKAVQADQERERQRRLEVER----------------- 167

  Fly   189 AAGGKKSTKPNNKKAKAKKL---AGGGDNELTIKPVNAVGSGGSGAIALGSKSTQKN------NQ 244
            .|..|:..|...|:||.::|   ....:.|...|..:|         ...||..|:.      ||
Mouse   168 EAEKKREAKQQAKEAKERELRKREKAEEKERRRKEYDA---------QKASKREQEKKPKKEANQ 223

  Fly   245 KKKNSKGD------------SWLNLLSRAALSSLVSFLVLFIINLLIIYMI--MFKNP------D 289
            ..|:..|.            ||      |.|..|:..|:|.:...|::..:  :.:.|      .
Mouse   224 APKSKSGSRPRKPPPRKHTRSW------AVLKVLLLLLLLCVAGGLVVCRVTGLHQQPLCTSVNT 282

  Fly   290 IADKLVEYI-PHQYRDWIL 307
            |.|..|:.: .|:...|:|
Mouse   283 IYDNAVQGLRHHEILQWVL 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3408	NP_648328.1	LRR	<21..>124	CDD:443914	58/102 (57%)
		leucine-rich repeat	44..66	CDD:275378	11/21 (52%)
		leucine-rich repeat	67..89	CDD:275378	14/21 (67%)
		leucine-rich repeat	90..112	CDD:275378	14/21 (67%)
		leucine-rich repeat	113..124	CDD:275378	7/10 (70%)
Lrrc59	NP_598568.1	LRR 1	10..31		8/20 (40%)
		LRR	<19..>126	CDD:443914	60/106 (57%)
		leucine-rich repeat	19..40	CDD:275378	11/20 (55%)
		LRR 2	40..62		10/21 (48%)
		leucine-rich repeat	41..63	CDD:275378	11/21 (52%)
		LRR 3	63..84		13/20 (65%)
		leucine-rich repeat	64..86	CDD:275378	14/21 (67%)
		LRR 4	86..107		12/20 (60%)
		leucine-rich repeat	87..109	CDD:275378	14/21 (67%)
		LRR 5	109..128		10/18 (56%)
		Atrophin-1	<140..>238	CDD:460830	25/123 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	150..241		22/116 (19%)