DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG3408 and Sur-8

DIOPT Version :9

Sequence 1:NP_648328.1 Gene:CG3408 / 39107 FlyBaseID:FBgn0036008 Length:331 Species:Drosophila melanogaster
Sequence 2:NP_001262665.1 Gene:Sur-8 / 42093 FlyBaseID:FBgn0038504 Length:694 Species:Drosophila melanogaster


Alignment Length:254 Identity:63/254 - (24%)
Similarity:105/254 - (41%) Gaps:52/254 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 NVKERVVDETCD--------LSLSELSEIPVREIASFKRVTVLDLSSNRLVNLGKNFSILTRLVR 69
            |..:::.|:..:        ||.:.|.:|| ..|.:.:::.:|||..||:..|.....:|..|.|
  Fly   472 NALQKLPDDIMNLQNLEILILSNNMLKKIP-NTIGNLRKLRILDLEENRIEVLPHEIGLLHELQR 535

  Fly    70 LDLSKNQIKFLPEDFGQLEQLRHLDLYNNCLEHLPISFGQLRRLRYLDLKGNPLTPAWEKIVGCC 134
            |.|..|||..||...|.|..|.||.:..|.|:.||...|.|..|..|.:..|   |..||:    
  Fly   536 LILQTNQITMLPRSIGHLGNLTHLSVSENNLQFLPEEIGSLESLENLYINQN---PGLEKL---- 593

  Fly   135 STQKDCQQAAKNTVSICANYKPEFIERERLAAQESQKMAGAGDSSANAVQTNGGAAGGKKSTKPN 199
                      ...:::|.|.|...|::..|:....:..|             ||.:...:..|.:
  Fly   594 ----------PFELALCQNLKYLNIDKCPLSTIPPEIQA-------------GGPSLVLQWLKMH 635

  Fly   200 NKKAKAKKLAG-------GGD--NELTIKPVN----AVGSGGSGAIALGSKSTQKNNQK 245
            :...:...:.|       |.|  .:..::.||    |.|:||.||.|.|..:::.::::
  Fly   636 SPYRQMXDVDGVWRTVYVGSDCYYQYELQTVNQAPGAGGNGGGGAAAAGGSASRSSDRR 694

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3408NP_648328.1 LRR_RI <43..>124 CDD:238064 30/80 (38%)
leucine-rich repeat 44..66 CDD:275378 7/21 (33%)
LRR_8 65..123 CDD:290566 23/57 (40%)
leucine-rich repeat 67..89 CDD:275378 11/21 (52%)
leucine-rich repeat 90..112 CDD:275378 9/21 (43%)
leucine-rich repeat 113..124 CDD:275378 3/10 (30%)
Sur-8NP_001262665.1 leucine-rich repeat 163..184 CDD:275380
leucine-rich repeat 185..207 CDD:275380
LRR_RI 204..401 CDD:238064
LRR_8 207..264 CDD:290566
leucine-rich repeat 208..230 CDD:275380
leucine-rich repeat 231..253 CDD:275380
LRR_8 252..310 CDD:290566
leucine-rich repeat 254..276 CDD:275380
leucine-rich repeat 277..299 CDD:275380
LRR_8 299..356 CDD:290566
leucine-rich repeat 300..322 CDD:275380
leucine-rich repeat 323..345 CDD:275380
LRR_8 344..403 CDD:290566
leucine-rich repeat 346..368 CDD:275380
leucine-rich repeat 369..392 CDD:275380
LRR_RI <379..566 CDD:238064 30/94 (32%)
leucine-rich repeat 417..440 CDD:275380
leucine-rich repeat 441..486 CDD:275380 2/13 (15%)
LRR_8 463..520 CDD:290566 12/48 (25%)
leucine-rich repeat 487..507 CDD:275380 6/20 (30%)
leucine-rich repeat 510..532 CDD:275380 7/21 (33%)
LRR_8 532..588 CDD:290566 23/58 (40%)
leucine-rich repeat 556..578 CDD:275380 9/21 (43%)
leucine-rich repeat 603..626 CDD:275380 6/35 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.910

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