DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3408 and lrrc59

DIOPT Version :9

Sequence 1:NP_648328.1 Gene:CG3408 / 39107 FlyBaseID:FBgn0036008 Length:331 Species:Drosophila melanogaster
Sequence 2:NP_998097.1 Gene:lrrc59 / 405868 ZFINID:ZDB-GENE-040426-2547 Length:314 Species:Danio rerio


Alignment Length:287 Identity:98/287 - (34%)
Similarity:149/287 - (51%) Gaps:38/287 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 DKAKVKVNVKERVVDETCDLSLSELSEIPVREIASFKRVTVLDLSSNRLVNLGKNFSILTRLVRL 70
            :|.|:: |:|:::.....|||||.|:|:||:|:|:|.:.|.||||.|.|:.|...|..||.|:::
Zfish     2 NKGKIE-NIKDKIDGNELDLSLSNLTEVPVKELAAFPKATFLDLSCNNLITLTPEFCSLTHLIKI 65

  Fly    71 DLSKNQIKFLPEDFGQLEQLRHLDLYNNCLEHLPISFGQLRRLRYLDLKGNPLTPAWEKIVGCCS 135
            ||:|||:..|||:.|||..|:|||||||.|:.|||.|.||:.|::||||.|||.|...|..|.|.
Zfish    66 DLNKNQLVCLPEEIGQLVNLQHLDLYNNKLKMLPIGFSQLKSLKWLDLKDNPLEPTLAKAAGDCL 130

  Fly   136 TQKDCQQAAKNT---VSICANYKPEFIERERLAAQESQKMAGAGDSSANAVQTNGGAAGGKKSTK 197
            .:|.|:|.|...   :.:......:.:||..|..:|.:|                     ||..|
Zfish   131 DEKQCRQCASRVLQHMKVLQEEAEKELERRLLKEREQEK---------------------KKEAK 174

  Fly   198 PNNKKAK---AKKLAGGGDNELTIKPVNAVGSGGSGAIALGSKSTQKNNQKKKNSKGDSWLNLL- 258
            ...|:|:   |:|.....:.|...|...|    ...|:|...:..:|..:|||.:..:...... 
Zfish   175 QREKEAREKEAQKKKKAEEKERKRKEYQA----QVAAVAAQEQQKKKKEEKKKKAAQNQGKKAAP 235

  Fly   259 -----SRAALSSLVSFLVLFIINLLII 280
                 ::.::.||...|:|.::.||:|
Zfish   236 ESVPKAKRSICSLFFSLLLKLVLLLVI 262

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3408NP_648328.1 LRR_RI <43..>124 CDD:238064 45/80 (56%)
leucine-rich repeat 44..66 CDD:275378 10/21 (48%)
LRR_8 65..123 CDD:290566 34/57 (60%)
leucine-rich repeat 67..89 CDD:275378 12/21 (57%)
leucine-rich repeat 90..112 CDD:275378 15/21 (71%)
leucine-rich repeat 113..124 CDD:275378 7/10 (70%)
lrrc59NP_998097.1 leucine-rich repeat 108..119 CDD:275378 7/10 (70%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 165..197 10/52 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 212..237 4/24 (17%)
LRR 1 14..35 10/20 (50%)
leucine-rich repeat 17..38 CDD:275378 12/20 (60%)
LRR 2 38..60 9/21 (43%)
leucine-rich repeat 39..61 CDD:275378 10/21 (48%)
LRR_8 60..118 CDD:290566 34/57 (60%)
LRR 3 61..82 10/20 (50%)
leucine-rich repeat 62..84 CDD:275378 12/21 (57%)
LRR_4 84..120 CDD:289563 23/35 (66%)
LRR 4 84..106 14/21 (67%)
leucine-rich repeat 85..107 CDD:275378 15/21 (71%)
LRR 5 107..126 10/18 (56%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 56 1.000 Domainoid score I11062
eggNOG 1 0.900 - - E2759_KOG0473
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 150 1.000 Inparanoid score I4347
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0007322
OrthoInspector 1 1.000 - - oto40624
orthoMCL 1 0.900 - - OOG6_108305
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R4209
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
ZFIN 00.000 Not matched by this tool.
109.750

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