Protein Alignment path and AVT1

DIOPT Version :10

• Sequence 1: NP_648327.1
• Gene: path / 39106
• FlyBaseID: FBgn0036007
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_012534.1
• Gene: AVT1 / 853457
• SGDID: S000003761
• Length: 602
• Species: Saccharomyces cerevisiae
• Alignment Length: 485
• Identity: 104/485 - (21%)
• Similarity: 187/485 - (38%)
• Gaps: 111/485 - (22%)

  Fly    30 IQPRKSDTEQALAG-------NDFDPFALR-----DNPHPT------TDNETLTHLLKASLGTGI 76
            ::|..|.||....|       ||.|...::     |....|      |..:|:.:.:...:|.|:
Yeast   162 LRPTASLTEMMSGGAGRRFTNNDMDSIVVKRVEGVDGKVVTLLAGQSTAPQTIFNSINVLIGIGL 226

  Fly    77 LGMPFAFMCSGLIMGIFSTIFTAF-ICTHC-SYVLVKCGHKLYYRTRRTKMTFAEIAEAAFQKGP 139
            |.:|.....:|.::|:  |:...| :.|.| :.:|.:|     ..|..|.:::|::..|||
Yeast   227 LALPLGLKYAGWVIGL--TMLAIFALATFCTAELLSRC-----LDTDPTLISYADLGYAAF---- 280

  Fly   140 KWCRGFAPVAKFSILFGLFLTYFGTCSVYTVIVASNFEQLISYWTGTAVSLRMLICIMLVPLILI 204
                |....|..|.||.|.|...|...|  ::...:...|...::.|  ..:::...::.|.:.|
Yeast   281 ----GTKGRALISALFTLDLLGSGVSLV--ILFGDSLNALFPQYSTT--FFKIVSFFIVTPPVFI 337

  Fly   205 AWVPNLKYLAPVSMVANVFM-------GLGLGITFYYLVQDLPP---VEERESVVWSTLPQFFSI 259
                      |:|:::|:.:       |..|.|....|.:...|   |...|:.:|....:...:
Yeast   338 ----------PLSVLSNISLLGILSTTGTVLVICCCGLYKSSSPGSLVNPMETSMWPIDLKHLCL 392

  Fly   260 TIFAMEAI---GVVMP-LENNMKTPQSFLGICGVLSQGMSGVTLIYMLLGFLGYLRYGSATGESI 320
            :|..:.|.   ..|.| |:.:|:.|..|.. |...:..::.||.|...:  :|:|.:|:...:.|
Yeast   393 SIGLLSACWGGHAVFPNLKTDMRHPDKFKD-CLKTTYKITSVTDIGTAV--IGFLMFGNLVKDEI 454

  Fly   321 TLNLPIEEWPAQTVKVLIS-------LAVYCTFGLQFFVCLEIIWD---------GIKEKCKKRP 369
            |.|:.:.|...:.|..|||       :|............|:::.:         .||.:..|..
Yeast   455 TKNVLLTEGYPKFVYGLISALMTIIPIAKTPLNARPIVSVLDVLMNVQHIDEAASAIKRRAAKGL 519

  Fly   370 TLVNYVLRTVLVTAAVVLAVAVPTIGPFMGLIGA-FCFSILGLIFPVVIEL------IVHWESGF 427
            .:.|.:...|:.   |::|:..|.....:..:|| .||:|. ||.|....|      |..||.
Yeast   520 QVFNRIFINVVF---VLIAINFPEFDKIIAFLGAGLCFTIC-LILPCWFYLRLCKTTIKPWER-- 578

  Fly   428 GKYNWILWKNAIITLC--------GIGALV 449
                    ....:|:|        |:||.:
Yeast   579 --------VACHVTICISVVLSTLGVGAAI 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
path	NP_648327.1	SLC5-6-like_sbd	56..456	CDD:444915	95/447 (21%)
AVT1	NP_012534.1	Aa_trans	206..601	CDD:279788	94/441 (21%)