Protein Alignment path and Slc38a3

DIOPT Version :10

• Sequence 1: NP_648327.1
• Gene: path / 39106
• FlyBaseID: FBgn0036007
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_076294.2
• Gene: Slc38a3 / 76257
• MGIID: 1923507
• Length: 505
• Species: Mus musculus
• Alignment Length: 473
• Identity: 109/473 - (23%)
• Similarity: 181/473 - (38%)
• Gaps: 87/473 - (18%)

  Fly     1 MVNIVDSGSKHAPQEMEQFLPGEGKVMYKIQPRKSDTEQALAGNDFDPFALRDNPHPTTDNETLT 65
            ||.:|.:| ||    :|..|| .|......| |..||:....|..|...:....|| .||.|..|
Mouse     9 MVELVPNG-KH----LEGLLP-VGVPTTDTQ-RTEDTQHCGEGKGFLQKSPSKEPH-FTDFEGKT 65

  Fly    66 -------HLLKASLGTGILGMPFAFMCSGLIMGIFSTIFTAFICTHCSYVLVKCGHKLYYRTRRT 123
                   :|..|.:|:||||:.:|...:|:|:.:|.....|.:.::..::|:|....:..|
Mouse    66 SFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGIVGIR---- 126

  Fly   124 KMTFAEIAEAAFQKGPKWCRGFAPVAKFSILFGLFLTYFGTCSVYTVIVAS----------NFEQ 178
                     |..|.|   .|.|....|.:....:.|...|..|.|..|:.|          |.|:
Mouse   127 ---------AYEQLG---YRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEK 179

  Fly   179 LISYWTGTAVSLRMLICI-MLVPLILIAWVPNLKYLAPVSMVANVFMGLGLGITFYYLVQDLPPV 242
            ..|.|......|.:|:.: :::||.|:..:..|.|.:..|:...||.   |....|...|...|:
Mouse   180 PASVWYMDGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFF---LIAVIYKKFQVPCPL 241

  Fly   243 -----------------EERESV---------VWSTLPQFFS----------ITIFAMEAIGVVM 271
                             ||:..:         .:.| |.:|:          |..||......|:
Mouse   242 AHNLANATGNFSHMVVAEEKAQLQGEPDTAAEAFCT-PSYFTLNSQTAYTIPIMAFAFVCHPEVL 305

  Fly   272 PLENNMKTPQSFLGICGVLSQGMSGVTLIYMLLGFLGYLR-YGSATGESITLNLPIEEWPA--QT 333
            |:...:|.| |...:..:.:..::.:.::|.|....|||. |.....|.:.....::.:..  ..
Mouse   306 PIYTELKDP-SKRKMQHISNLSIAVMYVMYFLAALFGYLTFYDGVESELLHTYSKVDPFDVLILC 369

  Fly   334 VKVLISLAVYCTFGLQFFVCLEIIWDGIKEKCKKRPTLVNYVLRTVLVTAAVVLAVAVPTIGPFM 398
            |:|.:.:||..|..:..|.....|...:.:. ::...|.:.::.|.|:|...:|.:..|.|....
Mouse   370 VRVAVLIAVTLTVPIVLFPVRRAIQQMLFQN-QEFSWLRHVLIATGLLTCINLLVIFAPNILGIF 433

  Fly   399 GLIGAFCFSILGLIFPVV 416
            |:|||.....|..|||.:
Mouse   434 GIIGATSAPCLIFIFPAI 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
path	NP_648327.1	SLC5-6-like_sbd	56..456	CDD:444915	92/418 (22%)
Slc38a3	NP_076294.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..48		5/21 (24%)
		Aa_trans	63..492	CDD:279788	88/411 (21%)