DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment path and Slc38a10

DIOPT Version :9

Sequence 1:	NP_001261634.1	Gene:	path / 39106	FlyBaseID:	FBgn0036007	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	XP_006534347.1	Gene:	Slc38a10 / 72055	MGIID:	1919305	Length:	1111	Species:	Mus musculus

Alignment Length:	433	Identity:	93/433 - (21%)
Similarity:	180/433 - (41%)	Gaps:	97/433 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 LTHLLKASLGTGILGMPFAFMCSGLIMGIFSTIFTAFICTH--CSYVLVKCGHKLYYRTRRTKMT 126
            :|:::.:.:|..:|.|||.|...|:::|....:|.::: ||  |.: |||..      :...:.|
Mouse    12 ITNVVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWM-THQSCMF-LVKSA------SLSKRRT 68

  Fly   127 FAEIAEAAFQKGPKWCRGFAPVAKFSILFGLFLTYFGTCSVYTVIV---ASN-FEQLISYWTGTA 187
            :|.:|..|:.|..|.      :.:.|:: ||.|   |:|..:.|::   .|| |..|:.......
Mouse    69 YAGLAFHAYGKAGKM------LVETSMI-GLML---GSCITFYVVIGDLGSNFFAPLLGLQVTRT 123

  Fly   188 VSLRMLICIMLVPLILIAWVPNLKYLAPVSMVANVFMGL----GLGITFYYLVQDLPPVEERESV 248
            |.:.:|..:.|..::            |:|:..|:...:    .:.:.||.:...:        :
Mouse   124 VRVFLLFAVSLFIVL------------PLSLQRNMMASIQSFSAMALLFYTVFMFV--------I 168

  Fly   249 VWSTLPQ-------------------FFSITIFAME--AIGVVMPLENNMKTPQSFLGICGVLSQ 292
            |.|:|..                   |..:.||.|.  ....|:|..:::..| |...:..:.:.
Mouse   169 VLSSLKHGLFSGQWLRQVSYIRWEGVFRCVPIFGMSFACQSQVLPTYDSLDEP-SVKTMSSIFAS 232

  Fly   293 GMSGVTLIYMLLGFLGYLRYGSATGESITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCLEII 357
            .::.||..|:::||.||:.:..||..::.::.|... ..:.::|...::|...|.:....|.:.:
Mouse   233 SLNVVTAFYVMVGFFGYVSFTDATTGNVLIHFPSNP-VTEMIRVGFVMSVAVGFPMMILPCRQAL 296

  Fly   358 WDGIKEKCKKRPTLV--NYV--LRTVLVTAAVVL-----AVAVPTIGPFMGLIGAFCFSILGLIF 413
            ...:.|:.:|..|..  .|:  ||..::|.:||.     .|.:|.:...:|..||...|::..|.
Mouse   297 NTLLFEQQQKDGTFAAGGYMPPLRFKVLTLSVVFGTMVGGVMIPNVETILGFTGATMGSLICFIC 361

  Fly   414 PVVIELIVHWESGFGKYNWILWKNA----IITLCGIGALVFGT 452
            |.:|....|             |||    ::...|:|.||..|
Mouse   362 PALIYKKAH-------------KNAPSAQVVLWVGLGILVVST 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
path	NP_001261634.1	SLC5-6-like_sbd	56..456	CDD:294310	93/433 (21%)
path	NP_001261634.1	SdaC	67..445	CDD:223884	87/421 (21%)
Slc38a10	XP_006534347.1	SLC5-6-like_sbd	6..381	CDD:382020	88/421 (21%)
		PTZ00121	<407..789	CDD:173412
		PTZ00449	<731..>991	CDD:185628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4715
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.760