Protein Alignment path and slc38a2

DIOPT Version :10

• Sequence 1: NP_648327.1
• Gene: path / 39106
• FlyBaseID: FBgn0036007
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001011056.1
• Gene: slc38a2 / 496466
• XenbaseID: XB-GENE-6258676
• Length: 493
• Species: Xenopus tropicalis
• Alignment Length: 472
• Identity: 106/472 - (22%)
• Similarity: 183/472 - (38%)
• Gaps: 98/472 - (20%)

  Fly    26 VMYKIQP----RKSDTEQALAGNDFDPFALRDNPHPTTDNETLTHLLKASLGTGILGMPFAFMCS 86
            |.:.::|    :|.:||..              |..|:...::.:|..|.:|:||||:.:|...:
 Frog    45 VHFLLEPTMSKKKCETEYL--------------PGTTSFGMSVFNLSNAIVGSGILGLSYAMANT 95

  Fly    87 GLIMGIFSTIFTAFICTHCSYVLVKC---GHKLYYRTRRTKMTFAEIAEAAFQKGPKWCRGFAPV 148
            |:.:.:...:|......:..::|:|.   |..|.|.                |.|.|   .|...
 Frog    96 GIALFMILLVFVTVFSLYSIHLLLKTANEGGSLLYE----------------QLGLK---AFGIP 141

  Fly   149 AKFSILFGLFLTYFGTCSVYTVIVASNFEQLIS------------YWTGTAVSLRMLICIMLVPL 201
            .|.:....:.|...|..|.|..||......:|.            |..|..:.:.:.:.|:| ||
 Frog   142 GKLAASGSVTLQNIGAMSSYLYIVKYELPLVIKALMDIKESNGEWYLNGDYLVIMVSLAIIL-PL 205

  Fly   202 ILIAWVPNLKYLAPVSMVANVFMGLGLGITFYYLVQDLPPVEERESVVWST-------------- 252
            .|:.   ||.||...|..:.:.|...|.:..|...:...|:|.......|:
 Frog   206 SLLR---NLGYLGYTSGFSPLCMVFFLIVVIYKKFEIPCPLEAMNMTSNSSSHDHMAHNETDDEM 267

  Fly   253 -LPQFF---SITIFAMEAI-------GVVMPLENNMKTPQSFLGICGVLSQGMSGVTLIYMLLGF 306
             .|::|   |.|::|:..:       ..|:|:...:| .:|...:..|.:.....:.::|:|...
 Frog   268 CKPKYFVFNSQTVYAVPILTFSFVCHPAVLPIYQELK-GRSRRRMMNVSNVSFFAMFIMYLLAAL 331

  Fly   307 LGYLRYGSATGESITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCLEIIWDGIKEK-CK-KRP 369
            .|||.:.|.. |...|:...:.:.|..:.|::.|||.....|...:.:..|...:.|. |. |..
 Frog   332 FGYLTFYSKV-EPELLHTYSKVFGAGVIFVVVRLAVLMAVTLTVPIVIFPIRSSLNELFCSGKDF 395

  Fly   370 TLVNYVLRTVLVTAAV-VLAVAVPTIGPFMGLIGAFCFSILGLIFPVVIELIVHWESGFGKYNWI 433
            ..:.::|.|.|:.|.. ||.:.||||....|.|||...::|..|.|          |.|  |..:
 Frog   396 AWIRHILITFLILAFTNVLVIFVPTIRDIFGFIGASAAAMLVFILP----------SAF--YIRL 448

  Fly   434 LWKNAIITLCGIGALVF 450
            :.|.::.::..||||:|
 Frog   449 VKKESMKSVQKIGALLF 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
path	NP_648327.1	SLC5-6-like_sbd	56..456	CDD:444915	100/438 (23%)
slc38a2	NP_001011056.1	Regulates protein turnover upon amino acid deprivation. /evidence=ECO:0000250	1..92		14/60 (23%)
		SLC5-6-like_sbd	65..482	CDD:444915	100/438 (23%)