DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment path and Slc36a3

DIOPT Version :9

Sequence 1:	NP_001261634.1	Gene:	path / 39106	FlyBaseID:	FBgn0036007	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_758462.2	Gene:	Slc36a3 / 215332	MGIID:	2665001	Length:	477	Species:	Mus musculus

Alignment Length:	417	Identity:	129/417 - (30%)
Similarity:	216/417 - (51%)	Gaps:	32/417 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 HLLKASLGTGILGMPFAFMCSGLIMGIFSTIFTAFICTHCSYVLVKCGHKLYYRTRRTKMTFAEI 130
            ||||:::|||.||:|.|...:||::|..|.:....:..||..:|:.|...|..|.:|:.:.:.|.
Mouse    58 HLLKSNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHLTQRLQRSFVNYEET 122

  Fly   131 AEAAFQKGPK-WCRGFAPVAKFSILFGLFLTYFGTCSVYTVIVASNFEQLI--SYWTG------- 185
            ...:.:..|. |.|..:...::.:.|.|.:|..|.||||.:.:|.|.:|::  :::|.
Mouse   123 TMYSLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFLADNLQQIMEEAHFTSNVCQPRQ 187

  Fly   186 -----TAVSLRMLICIMLVPLILIAWVPNLKYLAPVSMVANVFMGLGLGITFYYLVQ-----DLP 240
                 :.:..|..:..:|..|||:..:.|.:.|:..|.:|.:.....|.:.|.||:|     :||
Mouse   188 SLVMTSILDTRFYMLTILPFLILLVLIQNPQVLSIFSTLATITTLSSLALIFEYLIQTPHHSNLP 252

  Fly   241 PVEERESVVWSTLPQFFSITIFAMEAIGVVMPLENNMKTPQSFLGICGVLSQGMSGVTLIYMLLG 305
            .|..     |.|...||...||..|.:|:|:||::.||:||.|   ..||..|||.|..:|:.||
Mouse   253 LVAN-----WKTFLLFFGTAIFTFEGVGMVLPLKSQMKSPQQF---PAVLYLGMSFVIFLYICLG 309

  Fly   306 FLGYLRYGSATGESITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCLEIIWDGIKEKCKKRPT 370
            .|||:::|:.|..|||||||| .|..|:||::.|:.::.|:.|||.|..|||...:..:..:...
Mouse   310 TLGYMKFGTDTQASITLNLPI-CWLYQSVKLMYSVGIFFTYALQFHVPAEIIVPYVVSRVSENWA 373

  Fly   371 L-VNYVLRTVLVTAAVVLAVAVPTIGPFMGLIGAFCFSILGLIFPVVIELIVHWESGFGKYNWIL 434
            | |:..:||.||......||.:|.:...:.|:|:...|.|.:|.|.::|:...:.........:
Mouse   374 LFVDLTVRTALVCLTCFSAVLIPRLDLVISLVGSVSSSALAIIIPPLLEIATFYSENISCATIV- 437

  Fly   435 WKNAIITLCGIGALVFGTQAAIKDIVK 461
             |:.:|::.|:...|.||..|:.::.:
Mouse   438 -KDIMISILGLLGCVLGTYQALYEMTQ 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
path	NP_001261634.1	SLC5-6-like_sbd	56..456	CDD:294310	128/410 (31%)
path	NP_001261634.1	SdaC	67..445	CDD:223884	123/398 (31%)
Slc36a3	NP_758462.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	19..43
Slc36a3	NP_758462.2	SLC5-6-like_sbd	52..458	CDD:382020	128/410 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.930