Protein Alignment path and slc-36.4

DIOPT Version :9

• Sequence 1: NP_001261634.1
• Gene: path / 39106
• FlyBaseID: FBgn0036007
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_492453.1
• Gene: slc-36.4 / 186798
• WormBaseID: WBGene00010421
• Length: 481
• Species: Caenorhabditis elegans
• Alignment Length: 487
• Identity: 122/487 - (25%)
• Similarity: 215/487 - (44%)
• Gaps: 54/487 - (11%)

  Fly    23 EGKVMYKIQPR-----KSDTEQALAGNDFDPFAL---RDNPHPT--------------TDNETLT 65
            |.|::.:::..     .:|..|.....:||....   ||.|:.|              :....|.
 Worm     6 EQKILIELETMPFIVGPTDNGQERKQQEFDSMGAKNDRDRPNDTKSVISTLIARKTGISATSGLI 70

  Fly    66 HLLKASLGTGILGMPFAFMCSGLIMGIFSTIFTAFICTHCSYVLVKCGHKLYYRTRRTKMTFAEI 130
            :.:...:|.|...:..:|..:||..|:.......|:..:..:.:|.|...|........:.:.|:
 Worm    71 NFICGMIGPGCFSLAVSFKQAGLWGGLALVFIVGFLSLYSMHKIVNCSQYLAKSNGDQSLDYGEM 135

  Fly   131 AEAAFQKGPKWCRGFAPVAKFSILFGLFLTYFGTCSVYTVIVASNFEQLISYWTGTA-----VSL 190
            ||||.|...||.|....:||..|...|.....|..:|:.|...   |.:|..|...|     .|.
 Worm   136 AEAAMQNSYKWARKHGKLAKIVINACLLAFQLGVITVFMVFAV---EHVIEIWEFFADSPPPFSK 197

  Fly   191 RMLICIMLVPLILIAWVPNLKYLAPVSMVANV--FMGLGLGITFYYLVQDLPPVEERESVVWSTL 253
            .::|.:..||.:|:.::.::|.|..:.:..||  |..:.| ||...:|....|..|..||   |.
 Worm   198 CVMILMYFVPQMLLNFIGHMKLLTILCLFGNVIIFAAIVL-ITKELMVHTWYPTWELGSV---TG 258

  Fly   254 PQFFSIT----IFAMEAIGVVMPLENNMKTPQSFLGICGVLSQGMSGVTLIYMLLGFLGYLRYGS 314
            .:..|:.    |::.|...:|:|:||::|.|:...|..||||..|:.||::|..|||.||:.:|.
 Worm   259 IEGISLAAGALIYSFEGQAMVLPMENSLKYPKDMTGATGVLSTAMNLVTVLYAFLGFFGYVTFGP 323

  Fly   315 ATGESITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCLEIIWDGIKEKCKKRPTLVN----YV 375
            |...|:||||| ......::|.|:.|.::....:|.:|.::::...::.|..:...:|:    |.
 Worm   324 AVQGSLTLNLP-NSILTVSIKGLLVLKIFFGSAIQLYVIVQMLLPSLRSKISEDRKMVHRLLPYA 387

  Fly   376 LRTVLVTAAVVLAVAVPTIGPFMGLIGAFCFSILGLIFPVVIELIVHW-----ESGFGKYNWILW 435
            ||..|:..::.:|:.||.:...:.|:|.....::.||.|..::.:|..     :....|:...|.
 Worm   388 LRLGLMLISLCIALIVPNLMQIIPLVGITSGLLISLILPSFLDCMVFLPVFKKQGDMFKFYQKLI 452

  Fly   436 KNAIITLCGIGALVFGTQAAIKDIVKAYSNNE 467
            .|..:.:.|...|..|..::|.||:    ||:
 Worm   453 INVFLFVLGWFFLGAGLYSSIDDII----NND 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
path	NP_001261634.1	SLC5-6-like_sbd	56..456	CDD:294310	108/433 (25%)
		SdaC	67..445	CDD:223884	103/397 (26%)
slc-36.4	NP_492453.1	Aa_trans	62..471	CDD:279788	107/416 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.890