Protein Alignment path and F21D12.3

DIOPT Version :10

• Sequence 1: NP_648327.1
• Gene: path / 39106
• FlyBaseID: FBgn0036007
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_495532.2
• Gene: F21D12.3 / 174201
• WormBaseID: WBGene00017663
• Length: 496
• Species: Caenorhabditis elegans
• Alignment Length: 425
• Identity: 94/425 - (22%)
• Similarity: 178/425 - (41%)
• Gaps: 62/425 - (14%)

  Fly    72 LGTGILGMPFAFMCSGLIMGIFSTIFTAFICTHCSYVLVKCGHKLYYRTRR---TKMTFAEIAEA 133
            :|.|::.||.||..|||.|||...:..|....:..|:|.|..:|:..|...   .:..|.|:|:.
 Worm    58 VGGGVVAMPVAFKLSGLPMGILIMLTVAVSFEYTGYLLGKVWNKIMERNPHIGVCRKPFPEMAKR 122

  Fly   134 AFQKGPKWCRGFAPVAKFSILFGLFLTYFGTCSVYTVIVASNFEQLISYWTGT-AVSLRMLICI- 196
            .....         :.:|:.:.| .:|.||...||.::.|:.....||:.... ::|..::|.:
 Worm   123 TMGTN---------MQRFTSVLG-NVTQFGVSVVYLLLSANIIHFFISHVLHVDSISNCLVITVL 177

  Fly   197 --MLVPLILIA-----WVPNL-KYLAPVSMVANVFMGLGLGITFYYLVQDLPPVEERESVVWSTL 253
              ::.|..|:|     ||..: ..|..|..|.::..|:.|..|..:..... ||....|.:.|
 Worm   178 AFLIWPFTLLASPGEFWVVIVFAMLTTVIAVVSIHTGIALDSTACFSAVSY-PVTTSTSTILS-- 239

  Fly   254 PQFFSITIFAMEAIGVVMPLENNMKTPQSFLGICGVLSQGMSGVTLIYMLLGFLGYLRYGSATGE 318
               |.|.:||.....|...::::||.|:.|   ...:..|..||.::|:.|....::.||.:..:
 Worm   240 ---FGIFLFAFSGHYVFPTIQHDMKNPRDF---TKSIFAGFLGVVILYLPLCIFAFVVYGDSMTD 298

  Fly   319 SITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCLEIIWDGIKEKCKKRPTLVN------YVLR 377
            |:..::   :.|:..:...:.::.:|      .:.|.|:.:.:.::.:....:.:      .:.|
 Worm   299 SVIYSI---QSPSLQLLANLMISFHC------IMTLVIVINPLNQEVEHYAKISHAFGIGRVITR 354

  Fly   378 TVLVTAAVVLAVAVPTIGPFMGLIGAFCF----SILGLIFPVVIELIVHWESGFGKY-------- 430
            |:::...:.:|:.||...|.|.|:||...    ::|..:|.:..|.....|...||.
 Worm   355 TIVLFLVLFVALTVPDFQPVMNLVGASTIPMGCAVLPSLFYLYSEAATEEEWRKGKIPTLREVLD 419

  Fly   431 ---NWILWKNAIITLCGIGALVFGTQAAIKDIVKA 462
               ..:|..|.||....|...|.|:...:..::||
 Worm   420 RTDKTVLIINLIIIFGAILGGVLGSYQGVLKLIKA 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
path	NP_648327.1	SLC5-6-like_sbd	56..456	CDD:444915	92/417 (22%)
F21D12.3	NP_495532.2	SLC5-6-like_sbd	42..442	CDD:444915	90/411 (22%)