DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment path and Slc38a1

DIOPT Version :9

Sequence 1:	NP_001261634.1	Gene:	path / 39106	FlyBaseID:	FBgn0036007	Length:	471	Species:	Drosophila melanogaster
Sequence 2:	NP_620187.1	Gene:	Slc38a1 / 170567	RGDID:	69645	Length:	485	Species:	Rattus norvegicus

Alignment Length:	485	Identity:	101/485 - (20%)
Similarity:	189/485 - (38%)	Gaps:	97/485 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 QPRKSDTEQALAGNDFDPFALRDNPHPTTDNETLTHLLKASLGTGILGMPFAFMCSGLIMGIFST 95
            :.|:|.|...|.....|.:.    |..|:...::.:|..|.:|:||||:.||...:|:::.:...
  Rat    48 ESRRSLTNSHLEKRKCDEYI----PGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLILL 108

  Fly    96 IFTAFICTHCSYVLVKCGHKLYYRTRRTK-MTFAEIAEAAFQKGPKWCRGFAPVAKFSILFGLFL 159
            .....:..:...:|:.|       ::.|. |.:.::.|..          |....|..|.....|
  Rat   109 TSVTLLSIYSINLLLIC-------SKETGCMVYEKLGEQV----------FGTTGKLVIFGATSL 156

  Fly   160 TYFGTCSVYTVIVASNF----------EQLISYWTGTAVSLRMLICIMLVPLIL-IAWVPNLKYL 213
            ...|....|..||.:..          |:..|.|   .|..|:|:.::...:|| :..:.||.||
  Rat   157 QNTGAMLSYLFIVKNELPSAIKSLMGEEETFSAW---YVDGRVLVVMVTFGIILPLCLLKNLGYL 218

  Fly   214 APVSMVANVFMGLGLGITFYYLVQ------DLPPVE-ERESVVWSTLPQ--------FFSITIFA 263
            ...|       |..|....::|:.      .:|.:. |:.|.|.:.:..        |.|.|::|
  Rat   219 GYTS-------GFSLSCMVFFLIVVIYKKFQIPCMNGEQNSTVSANVTDACTPKYVTFNSKTVYA 276

  Fly   264 MEAIGV-------VMPLENNMK-TPQSFLGICGVLSQGMSGVTLIYMLLGFLGYL---------- 310
            :..|..       |:|:.:.:| ..|..:.:...:|  ...:.::|.|....|||
  Rat   277 LPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNIS--FFAMFVMYFLTAIFGYLTFYEKVQSDL 339

  Fly   311 --RYGSATGESITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCLEIIWDGIKEKCKKRPTLVN 373
              :|.| ||:.:.|          ||::.:.:||..|..:.||.....:::..|   |.:..|..
  Rat   340 LHKYQS-TGDILIL----------TVRLAVIVAVILTVPVLFFTVRSSLFELAK---KTKFHLCR 390

  Fly   374 YVLRTVLVTAAV-VLAVAVPTIGPFMGLIGAFCFSILGLIFPVVIELIVHWESGFGKYNWILWKN 437
            :||.|:::...: :|.:.:|::....|::|....::|..|.|..:.|.:..:.| .|....:|.
  Rat   391 HVLVTIILLVIINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITNQDG-DKNTQRIWA- 453

  Fly   438 AIITLCGIGALVFGTQAAIKDIVKAYSNNE 467
            |:....|:...:......|.|...:.||.|
  Rat   454 ALFLALGVLFSLISIPLVIYDWACSSSNGE 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
path	NP_001261634.1	SLC5-6-like_sbd	56..456	CDD:294310	90/447 (20%)
path	NP_001261634.1	SdaC	67..445	CDD:223884	88/425 (21%)
Slc38a1	NP_620187.1	SLC5-6-like_sbd	69..472	CDD:382020	90/447 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820