Protein Alignment path and SLC38A8

DIOPT Version :10

• Sequence 1: NP_648327.1
• Gene: path / 39106
• FlyBaseID: FBgn0036007
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001073911.1
• Gene: SLC38A8 / 146167
• HGNCID: 32434
• Length: 435
• Species: Homo sapiens
• Alignment Length: 471
• Identity: 98/471 - (20%)
• Similarity: 179/471 - (38%)
• Gaps: 115/471 - (24%)

  Fly    51 LRDNPHPTTDNETLTH------LLKASLGTGILGMPFAFMCSG---------------LIMGIFS 94
            |.:.|||.|...||:.      |:|::||.|:|..|:||..:|               ||.|:..
Human    11 LPEKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVI 75

  Fly    95 TIFTAFICTHCSY---VLVKCGHKLYYRTRRTKMTFAEIAEAAFQKGPKWCRGFAPVAKFSILFG 156
            ..:.|.:....:|   |...||..:           .::.||.|                  |..
Human    76 LGYAAAVSGQATYQGVVRGLCGPAI-----------GKLCEACF------------------LLN 111

  Fly   157 LFLTYFGTCSV-YTVIVASNFEQLI-SYWTGT-----------AVSLRMLICIMLVPLILIAWVP 208
            |.:     .|| :..::....|:|. |..:||           ..:|.:|..::::||.....:.
Human   112 LLM-----ISVAFLRVIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIA 171

  Fly   209 NLKYLAPVSMVANVFMGLGLGITFYYLVQDLPPVEERES------VVWSTLPQFFSITIFAMEAI 267
            ..||.:.:..:|..::.|.:.:.:|...|.|    .|||      ..|:::...|....|..:..
Human   172 FQKYTSILGTLAACYLALVITVQYYLWPQGL----VRESHPSLSPASWTSVFSVFPTICFGFQCH 232

  Fly   268 GVVMPLENNM-KTPQSFLGICGVLSQGMSGVTLIYMLLGFLGYLRYGSATGESITLNLPIEEWPA 331
            ...:.:..:| |...|...:..|||  :....|||.|.|..|:|.:|:.....:.::.|..:...
Human   233 EAAVSIYCSMRKRSLSHWALVSVLS--LLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVI 295

  Fly   332 QTVKVLISLAVYCTFGLQFFVCLEIIWDGIKEKC----------KKRPTLVNYVLRTVLVTAAVV 386
            ...:||.::::...:.:..|:...::.|..:..|          ......|...|..:.||..:.
Human   296 IVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLA 360

  Fly   387 LAVAVPTIGPFMGLIGA------FCFSILGLIFPVVIELIVHWESGFG---KYNWILWKNAIITL 442
            :|:.:|.:...:.:||.      |.|..|.||..:.:|.|       |   |....:|  .::::
Human   361 MALFMPDLSEIVSIIGGISSFFIFIFPGLCLICAMGVEPI-------GPRVKCCLEVW--GVVSV 416

  Fly   443 CGIGALVFG--TQAAI 456
            . :|..:||  |.||:
Human   417 L-VGTFIFGQSTAAAV 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
path	NP_648327.1	SLC5-6-like_sbd	56..456	CDD:444915	95/464 (20%)
SLC38A8	NP_001073911.1	SLC5-6-like_sbd	23..431	CDD:444915	92/457 (20%)