Protein Alignment path and SLC38A6

DIOPT Version :10

• Sequence 1: NP_648327.1
• Gene: path / 39106
• FlyBaseID: FBgn0036007
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_001166173.1
• Gene: SLC38A6 / 145389
• HGNCID: 19863
• Length: 521
• Species: Homo sapiens
• Alignment Length: 491
• Identity: 99/491 - (20%)
• Similarity: 190/491 - (38%)
• Gaps: 117/491 - (23%)

  Fly    31 QPRKSDTEQ--ALAGNDFDPFALRDNPHPTTDNETLTHLLKASLGTGILGMPFAFMCSGLIMGIF 93
            ||.:::.|:  .|..|:..    |......:...::.:|:.|.:|:||||:.:....:|:....|
Human    20 QPEEAEAEELSPLLSNELH----RQRSPGVSFGLSVFNLMNAIMGSGILGLAYVLANTGVFGFSF 80

  Fly    94 STIFTAFICTHCSYVLVKCGHKLYYRTRRTKMTFAEIAEAAFQKGPKWCRGFAPVAKFSILFGLF 158
            ..:..|.:.::..::|:    .:..:|..|  ::.::...||        |..  .|..:...:.
Human    81 LLLTVALLASYSVHLLL----SMCIQTAVT--SYEDLGLFAF--------GLP--GKLVVAGTII 129

  Fly   159 LTYFGTCSVYTVIVASNFEQLIS---------YWTGTAVSLRMLICIMLV-PLILIAWVPNLKYL 213
            :...|..|.|.:|:.:.....|:         ||.....:|.::||:.:| ||.|:..:..|.|.
Human   130 IQNIGAMSSYLLIIKTELPAAIAEFLTGDYSRYWYLDGQTLLIIICVGIVFPLALLPKIGFLGYT 194

  Fly   214 APVSMVANVFMGLGL---------GITFYYLVQDLPPVEERESVVWSTLPQFFSI---TIFAMEA 266
            :.:|....:|..|.:         .:|..|:.:..    :..:|.....|:.|..   :.:|:..
Human   195 SSLSFFFMMFFALVVIIKKWSIPCPLTLNYVEKGF----QISNVTDDCKPKLFHFSKESAYALPT 255

  Fly   267 IGV-------VMPLENNMKTPQSFLGICGVLSQGMSGVT--------LIYMLLGFLGYLRYGSAT 316
            :..       ::|:...:::|.         .:.|..||        |||.:....|||.:....
Human   256 MAFSFLCHTSILPIYCELQSPS---------KKRMQNVTNTAIALSFLIYFISALFGYLTFYDKV 311

  Fly   317 ------GESITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCLEIIWDGIKEKCKKRPTLVNYV 375
                  |.|..|:   .:....|||:.|..||..|..|..|            ..:|..|::.:.
Human   312 ESELLKGYSKYLS---HDVVVMTVKLCILFAVLLTVPLIHF------------PARKAVTMMFFS 361

  Fly   376 ------LRTVLVTAA-----VVLAVAVPTIGPFMGLIGAFCFSILGLIFPVVIELIVHWESGFGK 429
                  :|..|:|.|     |:||:.||.|....|::||...:.|..|||.:..|.:..|
Human   362 NFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSRE----- 421

  Fly   430 YNWILWKNAIITLCGIGALVFGTQAAIKDIVKAYSN 465
             :::.||.       :|.|:...:.|...::.|:.|
Human   422 -DFLSWKK-------LGGLILSHRLACSGVISAHCN 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
path	NP_648327.1	SLC5-6-like_sbd	56..456	CDD:444915	90/453 (20%)
SLC38A6	NP_001166173.1	SLC5-6-like_sbd	46..429	CDD:444915	88/439 (20%)