Protein Alignment path and SLC38A3

DIOPT Version :9

• Sequence 1: NP_001261634.1
• Gene: path / 39106
• FlyBaseID: FBgn0036007
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: NP_006832.1
• Gene: SLC38A3 / 10991
• HGNCID: 18044
• Length: 504
• Species: Homo sapiens
• Alignment Length: 542
• Identity: 112/542 - (20%)
• Similarity: 193/542 - (35%)
• Gaps: 162/542 - (29%)

  Fly     1 MVNIVDSGSKHAPQEMEQFLPGEGKVMYKIQPRKSDTEQALAGNDFDPFALRDNPHPTTDNETLT 65
            ||.:|.:| ||:...:....|..|.     |..:......:.|..|...:....|| .||.|..|
Human     9 MVELVPNG-KHSEGLLPVITPMAGN-----QRVEDPARSCMEGKSFLQKSPSKEPH-FTDFEGKT 66

  Fly    66 -------HLLKASLGTGILGMPFAFMCSGLIMGIFSTIFTAFICTHCSYVLVKCGHKLYYRTRRT 123
                   :|..|.:|:||||:.:|...:|:|:.:|.....|.:.::..::|:|....:..|
Human    67 SFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGVVGIR---- 127

  Fly   124 KMTFAEIAEAAFQKGPKWCRGFAPVAKFSILFGLFLTYFGTCSVYTVIVAS----------NFEQ 178
                     |..|.|   .|.|....|.:....:.|...|..|.|..|:.|          |.|:
Human   128 ---------AYEQLG---YRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEE 180

  Fly   179 LISYWTGTAVSLRMLICI-MLVPLILIAWVPNLKYLAPVSMVANVFMGLGLGITFYYLVQDLPP- 241
            ..|.|......|.:|:.: :::||.|:..:..|.|.:..|:...||..:.:....:::...|||
Human   181 KTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPN 245

  Fly   242 ----------VE----------ERESVVWSTLPQFFS----------ITIFAMEAIGVVMPLENN 276
                      ||          |.|:..:.| |.:|:          |..||......|:|:...
Human   246 FNNTTGNFSHVEIVKEKVQLQVEPEASAFCT-PSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTE 309

  Fly   277 MKTPQSFLGICGVLSQGMSGVTLIYMLLGFLGYLR-YGSATGE---------------------- 318
            :|.| |...:..:.:..::.:.::|.|....|||. |.....|
Human   310 LKDP-SKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLILCVRVAV 373

  Fly   319 --SITLNLPIEEWPA-QTVKVLISLAVYCTFGLQFFVCLEIIWDGIKEKCKKRPTLVNYVLRTV- 379
              ::||.:||..:|. :.::.::            |...|..|             :.:||..|
Human   374 LTAVTLTVPIVLFPVRRAIQQML------------FPNQEFSW-------------LRHVLIAVG 413

  Fly   380 LVTAAVVLAVAVPTIGPFMGLIG----------------------------------AFCFSILG 410
            |:|...:|.:..|.|....|:||                                  |.||::||
Human   414 LLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAMLG 478

  Fly   411 -LIFPVVIE-LIVHWESGFGKY 430
             |:..:.:. :|:.|.||..::
Human   479 FLLMTMSLSFIIIDWASGTSRH 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
path	NP_001261634.1	SLC5-6-like_sbd	56..456	CDD:294310	100/487 (21%)
		SdaC	67..445	CDD:223884	95/469 (20%)
SLC38A3	NP_006832.1	Aa_trans	64..491	CDD:279788	92/469 (20%)
		SdaC	64..486	CDD:223884	92/464 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820