Protein Alignment path and slc38a4

DIOPT Version :10

• Sequence 1: NP_648327.1
• Gene: path / 39106
• FlyBaseID: FBgn0036007
• Length: 471
• Species: Drosophila melanogaster
• Sequence 2: XP_031753492.1
• Gene: slc38a4 / 100145209
• XenbaseID: XB-GENE-6459320
• Length: 542
• Species: Xenopus tropicalis
• Alignment Length: 542
• Identity: 106/542 - (19%)
• Similarity: 191/542 - (35%)
• Gaps: 154/542 - (28%)

  Fly     2 VNIVDSGSKHAPQEMEQFLPGEGKVMYKIQPRKSDTEQALAGNDFDPFALRDNPHPTTDNETLTH 66
            |.|....:....:|.::||                 ...|.....:.:....:|..|:...::.:
 Frog    33 VTICSQYAGEEDEESQKFL-----------------TNGLRKKSLEEYTEEHHPGTTSFGMSVFN 80

  Fly    67 LLKASLGTGILGMPFAFMCSGLIMGIFSTIFTAFICTHCSYVLVKC---GHKLYYRTRRTKMTFA 128
            |..|.:|:||||:.:|...:|:|:.||.....|.:..:..::|:|.   |..|.|.
 Frog    81 LGNAIMGSGILGLSYAMANTGIILFIFLLFGVAILSLYSVHLLLKTAKEGGSLIYE--------- 136

  Fly   129 EIAEAAFQKGPKWCRGFAPVAKFSILFGLFLTYFGTCSVYTVIVASNFEQLIS------------ 181
            ::.|.||....|       :|.||   .:.:...|..|.|..||.....::|.
 Frog   137 KLGEKAFGWPGK-------IAAFS---SITMQNIGAMSSYLFIVKYELPEVIRTFLRLEETSGEW 191

  Fly   182 YWTGTAVSLRMLICIMLVPLILIAWVPNLKYLAPVSMVANVFMGLGLGITFYYLVQ---DLP--- 240
            |..|..:.:.:.:.|:| ||.|:..:..|.|.:..|:...||.   :.:..|...|   .||
 Frog   192 YLNGNYLVILVSVGIIL-PLSLLKNLGYLGYTSGFSLTCMVFF---VSVVIYKKTQIPCPLPLLG 252

  Fly   241 ---------------PVEERESVVWSTL------------------------------------- 253
                           ||....:.|.|.:
 Frog   253 HNSGNMTSNHTYYTYPVMTENNTVVSGVNFMLEDTEGQQTGYEGHNMHKHSSDVEYEVHNDNKCQ 317

  Fly   254 PQFF---SITIFAMEAIGV-------VMPL--ENNMKTPQSFLGICGVLSQGMSGVTLIYMLLGF 306
            |::|   |.|.:|:..:..       |:|:  |...:|.:....:..|   .::.:.::|:....
 Frog   318 PKYFVFNSQTAYAIPILAFAFVCHPEVLPIYSELRRRTRKRMQNVANV---SIAAMLIMYLFAAL 379

  Fly   307 LGYLRYGSATGESITLNLPIEEWPAQTVKVLISLAVYCTFGLQFFVCL--------EIIWDGIKE 363
            .|||.:....|:.: |:..|:.:...|:.:.:.|||.....|...:.|        .:::.|
 Frog   380 FGYLTFIGEVGDEL-LHTYIKVYRFDTLLLCVRLAVLVAVTLTVPIVLFPIRSSVITMLFPG--- 440

  Fly   364 KCKKRPTLVNYVLRTVLVTAAVVLAVAVPTIGPFMGLIGAFCFSILGLIFPVVIELIVHWESGFG 428
              |....|.::::..|::.....|.:.||.|....|.|||...::|..|.|...
 Frog   441 --KPFSFLRHFLIALVILIFNNTLVIFVPAIKDIFGFIGASAATMLIFILPAAF----------- 492

  Fly   429 KYNWILWKNAIITLCGIGALVF 450
             |..|:.|.::.:...||||||
 Frog   493 -YLRIVKKESLRSPQKIGALVF 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
path	NP_648327.1	SLC5-6-like_sbd	56..456	CDD:444915	99/488 (20%)
slc38a4	XP_031753492.1	SLC5-6-like_sbd	70..524	CDD:444915	99/488 (20%)