DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jarid2 and PKDM7D

DIOPT Version :9

Sequence 1:	NP_648324.1	Gene:	Jarid2 / 39103	FlyBaseID:	FBgn0036004	Length:	2351	Species:	Drosophila melanogaster
Sequence 2:	NP_172338.5	Gene:	PKDM7D / 837384	AraportID:	AT1G08620	Length:	1223	Species:	Arabidopsis thaliana

Alignment Length:	801	Identity:	181/801 - (22%)
Similarity:	308/801 - (38%)	Gaps:	222/801 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  1639 ELVKTLLHAASNDAAS--------TTTSLKSLPKASTSAAAGAAAAPGASSLVRVNSNSSLFSGS 1695
            ||::..:...|:|..|        .|.:||.:..|:||   ..|..|...|:          |.:
plant    18 ELMRICVKEDSDDLPSVPPGFESYATFTLKRVVPATTS---DKAKTPAIESV----------SAT 69

  Fly  1696 AKSRTAAQTSSTAAAVAKKYK--------DDTPIKMANN---------------TAFPR------ 1731
            .:::...::....||.|.:.:        ||.....|||               .|.|:
plant    70 EQAKMEVESDEAKAARALRRRPWINHSGCDDDGDCAANNDNAASQNPDQNCDVKPALPKGVVRGC 134

  Fly  1732 -------------HDDPTQ---MVEAPIFRPTEKEFADPIEFIERITPIAARFGICKIIPPASFK 1780
                         |.|..:   :.:||:|.|:|:||.|.:.:|.:|.|.|.::|||:|:||.|:|
plant   135 EECKDCQKVTARWHPDEARRPDLEDAPVFYPSEEEFEDTLNYIAKIRPEAEKYGICRIVPPPSWK 199

  Fly  1781 PECRISDEM-----RFTAYNQYVHKMLHRWGPSAKELSAIKKYLATQSIVMNHPPWIGGMEVDLP 1840
            |.|.:.::.     :||...|.|.|:.:|        |::||
plant   200 PPCPLKEKQVWEGSKFTTRVQRVDKLQNR--------SSMKK----------------------- 233

  Fly  1841 RLYHTVQELGGLKEVIEKKKWARVAEEMCIPKLAQDRVTK-----------LDDIYCKYLLPYDT 1894
                    :..|...:.|||      ..|: |:..|.||.           ::::......|...
plant   234 --------ISKLPNQMRKKK------RKCM-KMGMDSVTNGMGDPCSASTGMNELETFGFEPGPG 283

  Fly  1895 LSPAERQKLFDEVEADWAKREARARRNADRFVNTESVSNEEDDLSSDEDEESEEEIDGVSMECIV 1959
            .:..:.||..||.:|.:.|:                     .:.|:|:             :|.|
plant   284 FTLKDFQKYADEFKAQYFKK---------------------SETSTDD-------------KCKV 314

  Fly  1960 KGRSMPLSQFYRIARNTMALWFKSTDPTVNEVEAEFWRHV--AVRDSHVCVHSGSIDSSGWGYGF 2022
            .              |::..|    :|.:.:||.|:||.|  |..:..| ::...:::..:|.||
plant   315 D--------------NSIDCW----EPALEDVEGEYWRIVDKATEEIEV-LYGADLETGVFGSGF 360

  Fly  2023 P----SPGPKGKGSNYARHPWNLKVLTNNSGSVLRSLG-PVMGVTVPTLHVGMLFSACCWYRDPH 2082
            |    |.........||:..|||.......||:|:..| .:.||.||.|::||.||:.||:.:.|
plant   361 PKISSSHNASSSEDKYAKSGWNLNNFPRLPGSLLKYEGSDISGVLVPWLYIGMCFSSFCWHVEDH 425

  Fly  2083 GLSWIEYLHTGASKLWYGIPDDQSANFRAALTSLIPTHCQNKTIWLPCDTVMVPPHMLTDRGVSL 2147
            .|..:.|:|.||.|||||:....:.....|:...:|...:.:...|......:.|..|...||.:
plant   426 HLYSLNYMHWGAPKLWYGVGGKDAVKLEEAMRKHLPDLFEEQPDLLHKLVTQLSPSKLKTAGVPV 490

  Fly  2148 CRIEQKPGEFIVVFPRAYTSSLATGYVVSESVYFATMSWLDLAKDDFRDIHESCEPAMFSLEQLL 2212
            .|..|..|||::.|||||.:...:|:..:|:|..|.:.||...:.......:.......|.::||
plant   491 HRCVQHAGEFVLTFPRAYHAGFNSGFNCAEAVNVAPVDWLPHGQIAIELYCQQGRKTSISHDKLL 555

  Fly  2213 FALGYDQRVNSEALHQMLPMLNDVCE---KESAAREQLRAAGVTSTEKVQAEKGQK--------A 2266
              ||..:.|........|...|.|..   |..:|::.:.|.  |...::..|:.::        |
plant   556 --LGAAREVVKADWELNLLRKNTVDNLRWKAFSAKDGILAK--TLKARIDMERTRREFLCNSSLA 616

  Fly  2267 KKQQQPPYKSIESECDLCRANLYISMV--RTEDGNIYCLQHALKNLNNGNIQAKQCK-------L 2322
            .|.......:.|.||.:|..:|::|..  |.......||.| :|.|         |.       .
plant   617 LKMHSNFDATNERECCICFFDLHLSAAGCRCSPEKYSCLTH-VKEL---------CSCPWVTKYF 671

  Fly  2323 IYAYNVDDIQQLIRQLQEKIN 2343
            ::.|::|::..|:..::.|::
plant   672 LFRYDIDELNVLVEAVEGKLS 692

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jarid2	NP_648324.1	JmjN	1740..1781	CDD:128818	19/40 (48%)
		ARID	1812..1893	CDD:279697	13/91 (14%)
		JmjC	2066..2181	CDD:202224	38/114 (33%)
		zf-C5HC2	2281..2334	CDD:280996	13/61 (21%)
PKDM7D	NP_172338.5	JmjN	161..193	CDD:367058	14/31 (45%)
		JmjC	408..524	CDD:334913	38/115 (33%)
		zf-C5HC2	631..683	CDD:367254	13/61 (21%)
		trpS	<807..>860	CDD:272975
		FYRN	1002..1046	CDD:128814
		FYRC	1052..1146	CDD:197781
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0055
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D664180at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10694
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920