DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jarid2 and AT5G46910

DIOPT Version :9

Sequence 1:	NP_648324.1	Gene:	Jarid2 / 39103	FlyBaseID:	FBgn0036004	Length:	2351	Species:	Drosophila melanogaster
Sequence 2:	NP_199502.2	Gene:	AT5G46910 / 834736	AraportID:	AT5G46910	Length:	787	Species:	Arabidopsis thaliana

Alignment Length:	766	Identity:	167/766 - (21%)
Similarity:	277/766 - (36%)	Gaps:	262/766 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly  1640 LVKTLLHAASNDAASTTTSLKSLPKAS------TSAAAGAAAAPGASSLV-RVNSNSSLFSGSAK 1697
            |.:..|....:|:.:.|....::.::.      |||:.|......:|..| :|:..|::..|..|
plant    19 LKRKKLQKMRSDSVNETVGFSTMARSGGDALRPTSASCGMRLRVTSSDTVSKVHGASTVRGGLMK 83

  Fly  1698 SRTAAQTSSTAAAVAKKYKDDTPIKMANNTAFPRHDDPTQMVEAPIFRPTEKEFADPIEFIERIT 1762
            .:           |.|...||  :|...           ::.|.|::|||::||.||:.::::|.
plant    84 EK-----------VEKLETDD--LKWTE-----------RLPECPVYRPTKEEFEDPLTYLQKIF 124

  Fly  1763 PIAARFGICKIIPPASFKPECRISDEMRFTAYNQYVHKMLHRWGPSA----KELSAIKKYLATQS 1823
            |.|:::|||||:.|                         |....|:.    ||.|..|  ..|:
plant   125 PEASKYGICKIVSP-------------------------LTATVPAGAVLMKEKSNFK--FTTR- 161

  Fly  1824 IVMNHPPWIGGMEVDLPRLYHTVQELGGLKEVIEKKKWARVAEEMCIPKLAQDRVTKLDDIYCKY 1888
                                  ||.|             |:||..     :.|:||        :
plant   162 ----------------------VQPL-------------RLAEWD-----SDDKVT--------F 178

  Fly  1889 LLPYDTLSPAERQKLFDEVEADWAKREARARRNADRFVNTESVSNEEDDLSSDEDEESEEEIDGV 1953
            .:...|.:..:.:|:.::|   :|:|
plant   179 FMSGRTYTFRDYEKMANKV---FARR--------------------------------------- 201

  Fly  1954 SMECIVKGRSMPLSQFYRIARNTMALWFKSTDPTVNEVEAEFWRHVAVRDSHVCVHSGSIDSSGW 2018
                ...|.|:|.|                      .:|.|||:.:|...:....::..:|.|.:
plant   202 ----YCSGGSLPDS----------------------FLEKEFWKEIACGKTETVEYACDVDGSAF 240

  Fly  2019 GYGFPSPG-PKGKGSNYARHPWNLKVLTNNSGSVLRSL-GPVMGVTVPTLHVGMLFSACCWYRDP 2081
            .   .:|| |.|...      |||..::....|.||.| ..:.|||.|.|::|||||...|:.:.
plant   241 S---SAPGDPLGSSK------WNLNKVSRLPKSTLRLLETSIPGVTEPMLYIGMLFSMFAWHVED 296

  Fly  2082 HGLSWIEYLHTGASKLWYGIPDDQSANFRAAL------TSLIPTHCQNKTI-WLPCDTVMVPPHM 2139
            |.|..|.|.|.||||.|||||...:..|...:      ..::.|:.::... .|...|.:.||..
plant   297 HYLYSINYQHCGASKTWYGIPGSAALKFEKVVKECVYNDDILSTNGEDGAFDVLLGKTTIFPPKT 361

  Fly  2140 LTDRGVSLCRIEQKPGEFIVVFPRAYTSSLATGYVVSESVYFATMSWLDLAKDDFRDIHESCEPA 2204
            |.|..|.:.:..||||||:|.|||||.:..:.|:...|:|.||...|.     .|..| .||..|
plant   362 LLDHNVPVYKAVQKPGEFVVTFPRAYHAGFSHGFNCGEAVNFAMGDWF-----PFGAI-ASCRYA 420

  Fly  2205 MFSLEQLLFALGYDQRVNSEALHQMLPMLNDVCEKESAAREQLRAAGVTSTEKVQAEKGQKAKKQ 2269
            ..:...|   |.:::.:..||:     :||...:.|:        ..:|.||.    .||::.|.
plant   421 HLNRVPL---LPHEELICKEAM-----LLNSSSKSEN--------LDLTPTEL----SGQRSIKT 465

  Fly  2270 Q-------------------------QPPYKSIESECDLCRANLYISMVRTE-DGNIYCLQHALK 2308
            .                         ...|.:|  .|.||:.:.|::.:..| ..:..||:|.:|
plant   466 AFVHLIRFLHLARWSLMKSGLCTGLVSNTYGTI--VCSLCKRDCYLAFINCECYSHPVCLRHDVK 528

  Fly  2309 NLN-----------NGNIQAKQCKLIYAYNVDDIQQLIRQLQEKINHKAAV 2348
            .|:           ..||:..:...:.....|.:..||...::...:.:::
plant   529 KLDLPCGTTHTLYLRDNIEDMEAAAMKFEKEDGVSDLITTDEDLYKYPSSI 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jarid2	NP_648324.1	JmjN	1740..1781	CDD:128818	18/40 (45%)
		ARID	1812..1893	CDD:279697	12/80 (15%)
		JmjC	2066..2181	CDD:202224	45/121 (37%)
		zf-C5HC2	2281..2334	CDD:280996	13/64 (20%)
AT5G46910	NP_199502.2	JmjN	102..138	CDD:128818	17/35 (49%)
		JmjC	280..403	CDD:202224	45/122 (37%)
		zf-C5HC2	500..551	CDD:280996	12/50 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0055
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D664180at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10694
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920