DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jarid2 and ELF6

DIOPT Version :9

Sequence 1:	NP_648324.1	Gene:	Jarid2 / 39103	FlyBaseID:	FBgn0036004	Length:	2351	Species:	Drosophila melanogaster
Sequence 2:	NP_196044.2	Gene:	ELF6 / 830303	AraportID:	AT5G04240	Length:	1340	Species:	Arabidopsis thaliana

Alignment Length:	723	Identity:	177/723 - (24%)
Similarity:	261/723 - (36%)	Gaps:	242/723 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly  1741 APIFRPTEKEFADPIEFIERITPIAARFGICKIIPPASFKPE----------------------- 1782
            ||:||||:.||||||.:|.:|...|:.|||||||||.. ||.
plant    16 APVFRPTDTEFADPIAYISKIEKEASAFGICKIIPPLP-KPSKKYVFYNLNKSLLKCPELVSDVD 79

  Fly  1783 ----CRISDEMRFTA----YNQYVHKMLHRWGPSAKELSAIKKYLATQSIVMNHPPWIGG----- 1834
                |: .|...||.    ..|.|.|.....|.|..:.|.:|:.            |..|
plant    80 ISKVCK-EDRAVFTTRQQELGQTVKKNKGEKGKSNSQRSGVKQV------------WQSGGVYTL 131

  Fly  1835 --MEVDLPRLYHTVQELGGLKE----VIEKKKWARVAEEMCIPKLAQDRVTKLDDIYCKYLLPYD 1893
              .|......|.|  :||.:||    |||...|....|:               .||.:|  ..|
plant   132 DQFEAKSKAFYKT--QLGTVKELAPVVIEALFWKAALEK---------------PIYIEY--AND 177

  Fly  1894 TLSPAERQKLFDEVE---ADWAKREARARRNADRFVNTESVSNEEDDLSSDEDEESEEEIDGVSM 1955
            ....|     |.|.|   ..:.:|:.|.|....|.......|.:..:.||.|.|::......:|.
plant   178 VPGSA-----FGEPEDHFRHFRQRKRRGRGFYQRKTENNDPSGKNGEKSSPEVEKAPLASTSLSS 237

  Fly  1956 ECIVKGRSMPLSQFYRIARNTMALWFKSTDPTVNEVEAEFWRHVAVRDSHVCVHSGSIDSSGWGY 2020
            :...|.::|.:                     |:|:|.                     ::||
plant   238 QDSSKQKNMDI---------------------VDEMEG---------------------TAGW-- 258

  Fly  2021 GFPSPGPKGKGSNYARHPWNLKVLTNNSGSVLRSL-GPVMGVTVPTLHVGMLFSACCWYRDPHGL 2084
                     |.||.:   |||:::..:.|||.|.: ..:.|||.|.:::|||||...|:.:.|.|
plant   259 ---------KLSNSS---WNLQMIARSPGSVTRFMPDDIPGVTSPMVYIGMLFSWFAWHVEDHEL 311

  Fly  2085 SWIEYLHTGASKLWYGIPDDQSANFR---------------AALTSLIPTHCQNKTIWLPCDTVM 2134
            ..:.|||||:.|.||.:|.|.:.:|.               ||||.|..            .|.:
plant   312 HSMNYLHTGSPKTWYAVPCDYALDFEEVIRKNSYGRNIDQLAALTQLGE------------KTTL 364

  Fly  2135 VPPHMLTDRGVSLCRIEQKPGEFIVVFPRAYTSSLATGYVVSESVYFATMSWLDLAKD-DFRDIH 2198
            |.|.|:...|:..||:.|.||||:|.|||:|....:.|:...|:..|.|..||::||: ..|...
plant   365 VSPEMIVASGIPCCRLVQNPGEFVVTFPRSYHVGFSHGFNCGEAANFGTPQWLNVAKEAAVRRAA 429

  Fly  2199 ESCEPAMFSLEQLLFAL--GYDQRVNSEALHQMLP--------------------------MLN- 2234
            .:..| |.|.:|||:.|  .:..||.    ..:||                          :||
plant   430 MNYLP-MLSHQQLLYLLTMSFVSRVP----RSLLPGGRSSRLRDRQREEREFLVKRAFVEDILNE 489

  Fly  2235 --------------------DVCEKESAAREQLRAAGVT--------STEKVQAEKGQKAKKQQQ 2271
                                |:..:.||.  .|.||||.        :..|.:.|:|.  .:.|.
plant   490 NKNLSVLLREPGSRLVMWDPDLLPRHSAL--ALAAAGVAGASAVSPPAVAKKELEEGH--SELQN 550

  Fly  2272 PPYKSIESECDLCRANLYISMVRTEDGNIYCLQHALKNLNNGNIQAKQCKLI---YAYNVDDIQQ 2333
            ....|:..|..|....|.......:||.:...|     ::.|.:....|.::   :...|...::
plant   551 KEKTSLLEELSLFMEKLNDVYYDDDDGLLNDFQ-----VDTGTLPCVACGVLGFPFMSVVQPSEK 610

  Fly  2334 LIRQLQEK 2341
            .::.|.|:
plant   611 ALKDLSER 618

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jarid2	NP_648324.1	JmjN	1740..1781	CDD:128818	24/39 (62%)
		ARID	1812..1893	CDD:279697	19/91 (21%)
		JmjC	2066..2181	CDD:202224	43/129 (33%)
		zf-C5HC2	2281..2334	CDD:280996	8/55 (15%)
ELF6	NP_196044.2	JmjN	17..50	CDD:396793	20/32 (63%)
		JmjC	292..411	CDD:396791	43/130 (33%)
		C2H2 Zn finger	1230..1255	CDD:275368
		C2H2 Zn finger	1253..1275	CDD:275368
		C2H2 Zn finger	1283..1305	CDD:275368
		C2H2 Zn finger	1313..1333	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	52	1.000	Domainoid score	I4277
eggNOG	1	0.900	-	-		E1_COG0055
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D664180at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10694
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920