DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jarid2 and JMJ14

DIOPT Version :9

Sequence 1:	NP_648324.1	Gene:	Jarid2 / 39103	FlyBaseID:	FBgn0036004	Length:	2351	Species:	Drosophila melanogaster
Sequence 2:	NP_193773.2	Gene:	JMJ14 / 827788	AraportID:	AT4G20400	Length:	954	Species:	Arabidopsis thaliana

Alignment Length:	693	Identity:	161/693 - (23%)
Similarity:	283/693 - (40%)	Gaps:	175/693 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  1703 QTSSTAAAVA-------KKYKDDTPIKMANNTAFPR---HDDPTQ-----MVEAPIFRPTEKEFA 1752
            |.:|.|.:||       :..|.::.::..:..:.|:   ..:|::     :.:||||.||.::|.
plant     3 QLASLAESVAMEEDSEKQSIKGESSLEPDSTPSSPKITARWNPSEACRPLVDDAPIFYPTNEDFD 67

  Fly  1753 DPIEFIERITPIAARFGICKIIPPASFKPEC-----RISDEMRFTAYNQYVHKMLHRWGPSAKEL 1812
            ||:.:||::...|..:|||:|:||.:::|.|     :|.:..:|....|::..:.:|
plant    68 DPLGYIEKLRSKAESYGICRIVPPVAWRPPCPLKEKKIWENSKFPTRIQFIDLLQNR-------- 124

  Fly  1813 SAIKKYLATQSIVMNHPPWIGGMEVDLPRLYHTVQELGGLKEVIEKKKWARVAEEMCIPKLAQDR 1877
            ..|||...|                                    ||:..|             |
plant   125 EPIKKSTKT------------------------------------KKRKRR-------------R 140

  Fly  1878 VTKLDDIYCKYLLPYDTLSPAERQKLFDEVEADWAKREARARRNADRFVNTESVSNEEDD----- 1937
            ::|:                                  ...||..|...:|.|..:.:.:
plant   141 ISKI----------------------------------GYTRRKRDSGCDTASSGSSDSEGKFGF 171

  Fly  1938 -LSSDEDEESEEEIDGVSMECIVKGRSMPLSQFYRIARNTMALWFKSTDPTVNEVEAEFWRHVAV 2001
             ...|...|..::.|....||..:....|.|   :.:.|      |...|.|.::|.|:||.|..
plant   172 QTGPDFTLEEFQKYDEYFKECYFQSEDHPGS---KASEN------KKFKPKVKDLEGEYWRIVEQ 227

  Fly  2002 RDSHVCVHSGS-IDSSGWGYGFP--SPG-PKGKGSNYARHPWNLKVLTNNSGSVLR-SLGPVMGV 2061
            ....|.|:.|: :::..:|.|||  .|| |..:...|::..|||..|:...||||. ....:.||
plant   228 ATDEVEVYYGADLETKKFGSGFPKYKPGYPISEADQYSQCGWNLNNLSRLPGSVLAFESCDISGV 292

  Fly  2062 TVPTLHVGMLFSACCWYRDPHGLSWIEYLHTGASKLWYGIPDDQSANFRAALTSLIPTHCQNKTI 2126
            .||.|:|||.||..||:.:.|.|..:.|||||..|:|||||.:.:.:|...:...:|...:.:..
plant   293 IVPWLYVGMCFSTFCWHVEDHHLYSMNYLHTGDPKVWYGIPGNHAESFENVMKKRLPDLFEEQPD 357

  Fly  2127 WLPCDTVMVPPHMLTDRGVSLCRIEQKPGEFIVVFPRAYTSSLATGYVVSESVYFATMSWLDLAK 2191
            .|......:.|.:|.:.||.:.|..|:.||||:.||:||.|....|:..:|:|..|.:.||
plant   358 LLHQLVTQLSPRILKEEGVPVYRAVQRSGEFILTFPKAYHSGFNCGFNCAEAVNVAPVDWL---- 418

  Fly  2192 DDFRDIHESCEPAMFSLEQLLFALGYDQRVNSEALH------------QMLPML---NDVCEKES 2241
                 :|.......:|.::...:|.:|:.:...|:.            :..|::   ..||.::.
plant   419 -----VHGQNAVEGYSKQRRKSSLSHDKLLLGAAMEATYCLWELSLSKKKTPVIARWKRVCSEDG 478

  Fly  2242 AAREQLRAAGVTSTEKVQAEK--------GQKAKKQQQPPYKSIESECDLCRANLYI--SMVRTE 2296
            ...:.::       ::||.|:        |...:|.:.......|.||.||..:|::  |..:..
plant   479 LLTKAVK-------KRVQMEEERLNHLQDGFSLRKMEGDFDNKRERECFLCFYDLHMSASSCKCS 536

  Fly  2297 DGNIYCLQHALKNLNNGNIQAKQCKLIYAYNVDDIQQLIRQLQ 2339
            .....||.|| |:|  .:.::|...::..:.:|::..|:|.|:
plant   537 PNRFACLIHA-KDL--CSCESKDRYILIRHTLDELWALVRALE 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jarid2	NP_648324.1	JmjN	1740..1781	CDD:128818	18/40 (45%)
		ARID	1812..1893	CDD:279697	9/80 (11%)
		JmjC	2066..2181	CDD:202224	42/114 (37%)
		zf-C5HC2	2281..2334	CDD:280996	13/54 (24%)
JMJ14	NP_193773.2	JmjN	56..96	CDD:128818	18/39 (46%)
		JmjC	296..412	CDD:202224	42/115 (37%)
		zf-C5HC2	519..571	CDD:280996	13/54 (24%)
		FYRN	743..784	CDD:128814
		FYRC	790..876	CDD:197781
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0055
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D664180at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10694
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920