Protein Alignment Jarid2 and kdm5bb

DIOPT Version :10

• Sequence 1: NP_648324.1
• Gene: Jarid2 / 39103
• FlyBaseID: FBgn0036004
• Length: 2351
• Species: Drosophila melanogaster
• Sequence 2: XP_005167081.1
• Gene: kdm5bb / 415256
• ZFINID: ZDB-GENE-030424-1
• Length: 1522
• Species: Danio rerio
• Alignment Length: 780
• Identity: 186/780 - (23%)
• Similarity: 294/780 - (37%)
• Gaps: 209/780 - (26%)

  Fly  1740 EAPIFRPTEKEFADPIEFIERITPIAARFGICKIIPPASFKP--ECRISDEMRFTAYNQYVHKML 1802
            |.|:|.|:.:||.||..||.:|.|||.:.||||:.||..::|  .|.: |.:.||...|.::::.
Zfish    14 ECPVFEPSWEEFKDPFAFINKIRPIAEKTGICKVRPPPDWQPPFACDV-DRLHFTPRIQRLNELE 77

  Fly  1803 HRWGPSAKELSAIKKYLATQSIVMNHPPWIGGMEVDLPRLYHTVQELGGLKEVIEKKKWARVAEE 1867
            .:.......|..|.|:...|...:. .|.:....:||.:|...|.:.||...|..:::|.::|..
Zfish    78 AQTRVKLNFLDQIAKFWDLQGCTLK-IPHVERKILDLYQLNKLVADEGGFDLVCRERRWTKIAMT 141

  Fly  1868 M----------------------------------------------------CIPKLAQDRVTK 1880
            |                                                    |:.| ..|.|..
Zfish   142 MGFAPGKAVGSHLRAHYERILYPYNLFQSGTNLLAPEFAVKLTGFGEPPVLEECLQK-PGDEVND 205

  Fly  1881 LDDIYCKY---------LLPYDTLSPAERQK-------LFDEVEADWAKREARARRNADRF-VNT 1928
            :|..|..:         |.|.:|.:||.|.|       .....|.:..:.:...||....| |.|
Zfish   206 IDKEYKPHDLLQRQNVPLQPSNTSAPARRAKRMKTESGCIKSEEGEGVENKPNLRRRMGSFVVKT 270

  Fly  1929 E-------SVSNEEDDLS--SDEDEESEEE-------------------------------IDG- 1952
            |       .|..|..::.  :.|.|:|:.:                               .||
Zfish   271 EQKKEIPIQVKEEPVEIKELNPEPEKSKPKKKNIPPPPVSMVDLYVCLVCGKGNDEDRLLLCDGC 335

  Fly  1953 --------------------------VSMECIVKGRSMPLSQFYR----IARNTMALWFKS---- 1983
                                      ::.||.....:....|.:|    .|...||..|||
Zfish   336 DDSYHTFCLIPPLTDVPKGDWRCPKCLTQECCKPQEAFGFEQAHRDYTLKAFGEMADSFKSDYFN 400

  Fly  1984 ----TDPTVNEVEAEFWRHVAVRDSHVCVHSGS-IDSSGWGYGFPSPGPKGK----GSNYARHPW 2039
                ..|| ..||.||||.|......|.|..|: |.|..:|.|||..|.:.|    ...|.:..|
Zfish   401 MPVHMVPT-ELVEKEFWRLVGTIQEDVTVEYGADIASKEFGSGFPIKGGRFKIAPHDEKYLQCGW 464

  Fly  2040 NLKVLTNNSGSVLRSL-GPVMGVTVPTLHVGMLFSACCWYRDPHGLSWIEYLHTGASKLWYGIPD 2103
            ||..:...:.|||..: ..:.|:|:|.|:|||.||:.||:.:.|....|.|||.|..|.|||.|.
Zfish   465 NLNNMAMMTPSVLTHVTADICGMTLPWLYVGMCFSSFCWHIEDHWSYSINYLHWGEPKTWYGAPG 529

  Fly  2104 DQSANFRAALTSLIPTHCQNKTIWLPCDTVMVPPHMLTDRGVSLCRIEQKPGEFIVVFPRAYTSS 2168
            ..:....|.:..|.|....::...|.....::.|:.|...||.:.|..|..|||::.|||:|.|.
Zfish   530 FAAEQLEAVMKKLAPELFDSQPDLLHQLVTIMNPNTLMAHGVPIYRTNQCAGEFVITFPRSYHSG 594

  Fly  2169 LATGYVVSESVYFATMSWLDLAK---DDFRDIHESCEPAMFSLEQLL--FALGYD--QRVNSEAL 2226
            ...|:..:|:|.|.|:.|:.|.:   |.:|.:|..|   :||.::::  .|:..|  ..|.:.|:
Zfish   595 FNQGFNFAEAVNFCTVDWMPLGRQCVDHYRQLHRYC---VFSHDEMVCNMAMKADCLDVVLASAV 656

  Fly  2227 HQMLPMLNDVCEKESAAREQLRAAGVTSTEKVQAEKGQKAKKQQQPPYKSI---ESECDLCRANL 2288
            .:.:.::   .::|...||::|..||...|..|              |..:   |.:|..||...
Zfish   657 QKDMQLM---IKEERELREKVRKMGVAQCELFQ--------------YDLLADDERQCVKCRTTC 704

  Fly  2289 YISMVR--TEDGNIYCLQHA-------LKNLNNGNIQAKQCKLIYAYNVDDIQQLIRQLQEKINH 2344
            |:|.:.  ...|...||.|.       :.|..          |.|.:.:||:..::..::::..:
Zfish   705 YLSALTCPCRPGVQVCLYHTHDLCSCPISNYT----------LNYRFTLDDLYPMMNAVRQRAEY 759

  Fly  2345  2344
            Zfish   760  759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jarid2	NP_648324.1	PHA03247	<157..429	CDD:223021
		Atrophin-1	762..>986	CDD:460830
		JmjN	1740..1781	CDD:128818	20/40 (50%)
		ARID_JARD2	1804..1915	CDD:350634	29/178 (16%)
		cupin_RmlC-like	2066..2181	CDD:477354	40/114 (35%)
		zf-C5HC2	2281..2334	CDD:460750	14/61 (23%)
kdm5bb	XP_005167081.1	JmjN	14..55	CDD:128818	20/40 (50%)
		ARID_KDM5B	77..166	CDD:350638	15/89 (17%)
		PHD1_KDM5B	316..361	CDD:277076	2/44 (5%)
		JmjC	491..607	CDD:396791	40/115 (35%)
		zf-C5HC2	697..749	CDD:460750	14/61 (23%)
		PLU-1	762..1098	CDD:462475
		PHD2_KDM5B	1189..1232	CDD:277080
		PHD3_KDM5B	1465..1513	CDD:277157