Protein Alignment Jarid2 and Kdm5c

DIOPT Version :10

• Sequence 1: NP_648324.1
• Gene: Jarid2 / 39103
• FlyBaseID: FBgn0036004
• Length: 2351
• Species: Drosophila melanogaster
• Sequence 2: NP_001406701.1
• Gene: Kdm5c / 317432
• RGDID: 1560601
• Length: 1554
• Species: Rattus norvegicus
• Alignment Length: 793
• Identity: 188/793 - (23%)
• Similarity: 295/793 - (37%)
• Gaps: 220/793 - (27%)

  Fly  1733 DDPTQMVEAPIFRPTEKEFADPIEFIERITPIAARFGICKIIPPASFKPECRIS-DEMRFTAYNQ 1796
            ||.....|.|:|.|:..||.||:.:|.:|.|||.:.|||||.|||.::|...:. |..|||...|
  Rat     6 DDFLPPPECPVFEPSWAEFRDPLGYIAKIRPIAEKSGICKIRPPADWQPPFAVEVDNFRFTPRIQ 70

  Fly  1797 YVHKMLHRWGPSAKELSAIKKYLATQSIVMNHPPWIGGME---VDLPRLYHTVQELGGLKEVIEK 1858
            .::::..:.......|..|.|:...|...:..|    .:|   :||..|...|.|.||.:.:.:.
  Rat    71 RLNELEAQTRVKLNYLDQIAKFWEIQGSSLKIP----NVERRILDLYSLSKIVVEEGGYETICKD 131

  Fly  1859 KKWARVAEEMCIPKLAQDRVTKLDDIYCKYLLPYDTLSPAE-----RQKLFDEVEAD-------- 1910
            ::|||||:.:..|. .::..:.|...|.:.:.||:......     ..:.||..|.|
  Rat   132 RRWARVAQRLNYPP-GKNIGSLLRSHYERIVYPYEMYQSGANLVQCNTRPFDNEEKDKEYKPHSI 195

  Fly  1911 -------------WAKREARAR----------------------------------------RNA 1922
                         :.:|..|.:                                        |..
  Rat   196 PLRQSVQPSKFNSYGRRAKRLQPDPEPTEEDIEKNPELKKLQIYGAGPKMMGLGLMAKDKNLRKK 260

  Fly  1923 DR-----------------FVNTESVSNE-----EDDLS-------------------------- 1939
            |:                 .|..||.|.:     :::||
  Rat   261 DKEGPECPPTVVVKEELGGDVKMESASPKTFLEGKEELSHSPEPCTKMTMRLRRNHSNAQFIESY 325

  Fly  1940 -------SDEDEE---SEEEIDGVSMECIV-------KG-------------------------R 1962
                   .|||::   .:...|...:.|::       ||                         |
  Rat   326 VCRMCSRGDEDDKLLLCDGCDDNYHIFCLLPPLPEIPKGVWRCPKCVMAECKRPPEAFGFEQATR 390

  Fly  1963 SMPLSQFYRIARNTMALWFK---STDPTVNEVEAEFWRHVAVRDSHVCVHSGS-IDSSGWGYGFP 2023
            ...|..|..:|.:..|.:|.   ...|| ..||.||||.|...:..|.|..|: |.|..:|.|||
  Rat   391 EYTLQSFGEMADSFKADYFNMPVHMVPT-ELVEKEFWRLVNSIEEDVTVEYGADIHSKEFGSGFP 454

  Fly  2024 SPGPK----GKGSNYARHPWNLKVLTNNSGSVLRSL-GPVMGVTVPTLHVGMLFSACCWYRDPHG 2083
            ....|    .:...||...|||.|:.....|||..: ..:.|:.||.|:|||:|||.||:.:.|.
  Rat   455 VSDSKRHLTPEEEEYATSGWNLNVMPVLEQSVLCHINADISGMKVPWLYVGMVFSAFCWHIEDHW 519

  Fly  2084 LSWIEYLHTGASKLWYGIPDDQSANFRAALTSLIPTHCQNKTIWLPCDTVMVPPHMLTDRGVSLC 2148
            ...|.|||.|..|.|||:|...:.:....:..|.|....::...|.....::.|:.|...||.:.
  Rat   520 SYSINYLHWGEPKTWYGVPSLAAEHLEEVMKKLTPELFDSQPDLLHQLVTLMNPNTLMSHGVPVV 584

  Fly  2149 RIEQKPGEFIVVFPRAYTSSLATGYVVSESVYFATMSWLDLAK---DDFRDIHESCEPAMFSLEQ 2210
            |..|..|||::.|||||.|....||..:|:|.|.|..||...:   :.:|.:...|   :||.|:
  Rat   585 RTNQCAGEFVITFPRAYHSGFNQGYNFAEAVNFCTADWLPAGRQCIEHYRRLRRYC---VFSHEE 646

  Fly  2211 LLFALG-----YDQRVNSEALHQMLPMLNDVCEKESAAREQLRAAGVTSTEKVQAEKGQKAKKQQ 2270
            |:..:.     .|..:.:....:|..|:    ::|...|:.|...|:|..|:...|.
  Rat   647 LICKMAACPEKLDLNLAAAVHKEMFIMV----QEERRLRKALLEKGITEAEREAFEL-------- 699

  Fly  2271 QPPYKSIESECDLCRANLYISMVRTED--GNIYCLQHALKNLNNGNIQAKQCK-------LIYAY 2326
               ....|.:|..|:...::|.:...|  ..:.||.|    :|:      .||       |.|.|
  Rat   700 ---LPDDERQCIKCKTTCFLSALACYDCPDGLVCLSH----IND------LCKCSSSRQYLRYRY 751

  Fly  2327 NVDDIQQLIRQLQ 2339
            .:|::..::.:|:
  Rat   752 TLDELPAMLHKLK 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jarid2	NP_648324.1	PHA03247	<157..429	CDD:223021
		Atrophin-1	762..>986	CDD:460830
		JmjN	1740..1781	CDD:128818	21/40 (53%)
		ARID_JARD2	1804..1915	CDD:350634	27/139 (19%)
		cupin_RmlC-like	2066..2181	CDD:477354	42/114 (37%)
		zf-C5HC2	2281..2334	CDD:460750	14/61 (23%)
Kdm5c	NP_001406701.1	JmjN	13..54	CDD:128818	21/40 (53%)
		ARID_KDM5C_5D	79..170	CDD:350639	23/95 (24%)
		PHD1_KDM5C_5D	326..371	CDD:277077	7/44 (16%)
		JmjC	501..617	CDD:396791	42/115 (37%)
		zf-C5HC2	707..759	CDD:460750	14/61 (23%)
		PLU-1	772..1100	CDD:462475
		PHD_SF	1187..1247	CDD:473978