Protein Alignment Jarid2 and msc1

DIOPT Version :10

• Sequence 1: NP_648324.1
• Gene: Jarid2 / 39103
• FlyBaseID: FBgn0036004
• Length: 2351
• Species: Drosophila melanogaster
• Sequence 2: NP_593431.1
• Gene: msc1 / 2541710
• PomBaseID: SPAC343.11C
• Length: 1588
• Species: Schizosaccharomyces pombe
• Alignment Length: 792
• Identity: 157/792 - (19%)
• Similarity: 286/792 - (36%)
• Gaps: 247/792 - (31%)

  Fly  1685 VNSNSSLFS--GSAKSRTAAQ---------TSSTA----------AAVAKKYKDDTPIKMANNTA 1728
            :|.:|::||  ..||..|..|         |:||.          .||....|::..:::.
pombe    26 LNVHSNIFSELEHAKPSTQQQQQQQNISNETTSTGPRICISRDEFKAVNLLTKEEINVRVT---- 86

  Fly  1729 FPRHDDPTQMVEAPIFRPTEKEFADPIEFIERITPIAAR-FGICKIIPPASFK------------ 1780
                             |.::||:..::||..:....|| .|..::|||.::|
pombe    87 -----------------PKKEEFSRGLDFISDLYDQTARKSGAVRVIPPDNWKCPLTINTTTFKF 134

  Fly  1781 ----------------PECRISDEMRFTAYNQYVHK-----MLHRWGPSAKELS--AIKKYLAT- 1821
                            |...||.:.:|...::.:.|     .:::...:|:..|  .::.|.:.
pombe   135 LTRKNNPSSMSLVSNYPLDAISSQQKFHGNDKTLEKNSAKATINKSNSTAETSSTATVEPYDSND 199

  Fly  1822 --------QSIVMNHPPWIGGMEVDLPRLYHTVQELGGLKEVIEKKKWA---------------- 1862
                    .::|::: .::.|..|||.::...:| |...|.::|.:.|:
pombe   200 LYRIFDRPDAVVLSY-IFVLGKAVDLLQIKQWLQ-LSKQKNLLEFEFWSQAAQHYKLDVNSLRNA 262

  Fly  1863 --------------------------RVAEEMCIPK---LAQDRVTKLDDIYCKYLLPY------ 1892
                                      ||..:..|||   .||:..:.:....|:....|
pombe   263 YNLYAETGVTTRTGNDGGSPINRPAKRVKRQNHIPKCKLCAQEGSSLVTCCICQSNYHYACVEAP 327

  Fly  1893 ------------DTLSPAERQKLFDEVEADWAKREARARRNADRFVNTESVSNEEDDLSSDEDEE 1945
                        ::..|:..:.|:.||:                :....|.....::|:|...::
pombe   328 FAPFSDIHYWTCNSCIPSSLKILWKEVD----------------YHCISSFLQSSNELASSLKKQ 376

  Fly  1946 SEEEIDGVSMECIVKGRSMPLS--QFYRIARNTMALWFKS-------TD----PTVNEVEAEFWR 1997
            ....:....:......::.|.|  |..|..|:|....|::       :|    .|::.:|..||
pombe   377 LPSFLAQTPLTLPSNTKTPPASARQSSRRTRSTSGKGFETKISINLDSDIKLLNTLSPLETFFW- 440

  Fly  1998 HVAVRDSHVCVH--SGSIDSSGWGY---GFPSP----------GPKGKGSNYARHPWNLKVLTNN 2047
                     |..  |.:..||.:.|   ..|:|          .|..:.:.|...||||..:..:
pombe   441 ---------CCSFPSTASTSSPFSYYPESLPTPLLGRAVNTTAFPTSRQNAYYNDPWNLYFIHFS 496

  Fly  2048 SGSVLRSLGPVMGVTVPTLHVGMLFSACCWYRDPHGLSWIEYLHTGASKLWYGIPDDQSANFRAA 2112
            ..|.||...|  |:...|:.:|...:...|.||...|..:.|.|.||.::||.||:.....:...
pombe   497 KLSPLRFTPP--GILTSTISLGQPLTCQGWQRDSMSLFGMHYHHYGAQRIWYVIPEVDGPKYEKL 559

  Fly  2113 LTSLIPTHCQNKTIWLPCDTVMVPPHMLTDRGVSLCRIEQKPGEFIVVFPRAYTSSLATGYVVSE 2177
            |..|.|:..|.|...|....:::|..||...|:.:....|...||::..|..|.:.|.||:.:||
pombe   560 LNDLSPSFIQEKPETLIKSKILLPISMLISNGIQVLTFVQNSNEFVITSPNTYYTVLDTGFSLSE 624

  Fly  2178 SVYFATMSWL-DLAKDD----FRDIHESCEPAMFSLEQLLFA-LGYDQRVNSEALHQMLPMLNDV 2236
            ||.|||..|: |:..::    ::::|.|   |.|||:.:|.| ...|:.|:|  .:.::..|.|.
pombe   625 SVPFATKEWIQDMHAENSFNMYKNLHIS---APFSLDHILLANATLDKTVHS--AYWLMTCLKDR 684

  Fly  2237 CEKESAAREQLRAAGVTSTEKVQAEKGQKAKKQQQP-------PYKSIESECDLCRANLYISMVR 2294
            .::|...|.:.|                    ::.|       |.:|....|..|:...|::.:.
pombe   685 VDRELTLRNEFR--------------------KRHPLLTWIPTPLESSVMACAFCKTFAYLASIE 729

  Fly  2295 TEDG-NIYCLQH 2305
            .::| ...||.|
pombe   730 EKNGTKTACLSH 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jarid2	NP_648324.1	PHA03247	<157..429	CDD:223021
		Atrophin-1	762..>986	CDD:460830
		JmjN	1740..1781	CDD:128818	12/69 (17%)
		ARID_JARD2	1804..1915	CDD:350634	26/184 (14%)
		cupin_RmlC-like	2066..2181	CDD:477354	35/114 (31%)
		zf-C5HC2	2281..2334	CDD:460750	7/26 (27%)
msc1	NP_593431.1	JmjN	80..123	CDD:128818	11/63 (17%)
		PHD_SF	299..342	CDD:276966	4/42 (10%)
		JmjC	513..628	CDD:396791	35/114 (31%)
		zf-C5HC2	716..764	CDD:460750	7/26 (27%)
		PLU-1	780..1131	CDD:462475
		PHD_Ecm5p_Lid2p_like	1173..1217	CDD:276993
		PHD_SF	1457..1502	CDD:473978