Protein Alignment Jarid2 and jmjd-3.2

DIOPT Version :9

• Sequence 1: NP_648324.1
• Gene: Jarid2 / 39103
• FlyBaseID: FBgn0036004
• Length: 2351
• Species: Drosophila melanogaster
• Sequence 2: NP_510405.1
• Gene: jmjd-3.2 / 181543
• WormBaseID: WBGene00009089
• Length: 867
• Species: Caenorhabditis elegans
• Alignment Length: 1169
• Identity: 218/1169 - (18%)
• Similarity: 356/1169 - (30%)
• Gaps: 432/1169 - (36%)

  Fly  1282 KSESAWSAKGPSLKATPVLVTP---PNRKELHEQADSKDCDALDYDKSSTPVNLTQKITSNESLA 1343
            |:|....|:.|    .|..:.|   .::.|:.|:.....|  .|.|         |....|.|..
 Worm    16 KTEQLVDAQYP----VPTTLKPDFFTDKTEIDERNRVDQC--FDND---------QPFNGNNSKL 65

  Fly  1344 VEKKVNDRKGKESAKAAASKAATQPRSTAATPPTPIS----------STPTPASLTPSKSSP--- 1395
            :|        .||.|...|  :|:|..|.      ||          |..|...:.|....|
 Worm    66 LE--------SESHKLGES--STEPSGTT------ISSGNYEIAEDCSDETEQFIDPDNQVPAAN 114

  Fly  1396 -------TPPPAVKQKAEKGKRN---ATAGGGATALASPPAAPTPANPKRTPVYNQKNAKAQQQQ 1450
                   |.....|.:.|.|..:   :|...|:|                    |::....|...
 Worm   115 FITNDCTTIEQTAKIQEESGTDSLIVSTNDSGST--------------------NEQILPTQSND 159

  Fly  1451 AETKPASNPPSGAGTKRESVYAFGKD--DESGSK----SGN--RRRTDPSPVPAPALVPNALSER 1507
            |:.             ||.:...|:|  |:.|:.    |||  :.|...|......||
 Worm   160 ADF-------------RERIEIDGRDQVDQHGNSYPPISGNNSKLRKSESHEQGEFLV------- 204

  Fly  1508 SPTKKRAAAAAAATAVQLTLSPTENCKIEGKPSKAPTGRGAKKQQQ-QAPAPPAPPVEASGDSDA 1571
            .|::||              .|....:.:.|..|:..||.:.|..| |..       :.|.|.:|
 Worm   205 GPSRKR--------------KPETLIETKSKKRKSARGRPSNKLNQFQIH-------QVSSDWNA 248

  Fly  1572 EGATFYIPLQGAGVGGSGDGGIQGVAVKLGREGPDGPNQKVVMQATLVTK---AQMDTNSKPLPE 1633
            .....:.....||                           .::::....|   ||::..|:|...
 Worm   249 NAFLQFARRDAAG---------------------------TILESEEAKKTIDAQLEHFSEPSCS 286

  Fly  1634 S--------------LNTNELVKTLLHAASNDAASTTTSLKSLPK--------ASTSAAAGAAAA 1676
            :              |.||:|....:...|| ..|...||..|||        ...|.:.|....
 Worm   287 TDVSVHVVRDNENLGLVTNKLRSLAIPPISN-LPSDLPSLYKLPKLFLTGATFMDVSKSKGKQVI 350

  Fly  1677 PGASSLVRVNSN--------SSLFSGSAKSRTAAQ-TSSTAAAVAKK--YKDDTPI-KMANNTAF 1729
            ..||..::...|        |.||..:.|..|..: ..:|:.....|  |:...|| .:.||:
 Worm   351 TKASKWIKSGKNLVYETSGCSELFDETTKFNTDGKIEENTSEEYTNKDQYRLPVPIYNIENNS-- 413

  Fly  1730 PRHDDPTQMVE-------APIFRPTEKEFADPIEFIERITPIAARFGICKIIPPASFKPECRISD 1787
               |:.:..::       ..|||..|:.|.     ::|.|     |.|..:.|
 Worm   414 ---DETSNFIKNIVNTTTMCIFRGIEEAFG-----MDRQT-----FDISTLAP------------ 453

  Fly  1788 EMRFTAYNQYVHKMLHRWGPSAKELSAIKKYLATQSIVMNHPPWIGGMEVDLPRLYHTVQELGGL 1852
                 .|..|..| :.|..|.:   ||...|:..:                     :|||.||
 Worm   454 -----LYPDYPLK-IRRQMPQS---SATNFYMNDK---------------------NTVQRLG-- 486

  Fly  1853 KEVIEKKKWARVAEEMCIPKLAQDRVTKLDDIYCKYLLPYDTLSPAERQKLFDEVEADWAKREAR 1917
                  ..||....|         .||:|.|    :...|::|....|           :..:|.
 Worm   487 ------NAWAVFDFE---------GVTQLRD----FAKNYESLKDIGR-----------SAYQAI 521

  Fly  1918 ARRNADRFVNTESVSNEEDDLSSDEDEESEEEIDGVSMECIVKGRSMPLSQFYRIA--RNTMALW 1980
            .|       |..:.|...||:...                 :|..::|||..:::.  .|...|.
 Worm   522 LR-------NPSAFSEVMDDMKKQ-----------------IKENTIPLSPEHKLTVHENATVLA 562

  Fly  1981 FKST----DPTVNEVEAEFWRHVAVRDSHVCVHSGSIDSSGWGYGFPSPGPKGKGS--NYARHPW 2039
            |.:.    |....|...|      ::....|:.                 |.|.|:  |:|:.
 Worm   563 FGTNIDLDDQRFKEQLDE------IKKLPDCLR-----------------PDGAGNLLNFAQE-- 602

  Fly  2040 NLKVLTNNSGSVLRSLGPVMGVTVPTLHVGMLFSACCWYRDPHGLSWIEYLHTGASKLWYGIPDD 2104
                             .:.|:..|.::.....:....:.:...|..|...|.....:|||:|.:
 Worm   603 -----------------SLAGLNKPQVYCKPPGARTTAHLENQALGSININHGPGDCVWYGVPME 650

  Fly  2105 QSANFRAALTSLIPTHCQN--KTIWLPCDTVMVPPHMLTDRGVSLCRIEQKPGEFIVVFPRAYTS 2167
            .|.....    ||..|..|  |:.:.|.:      ..|.:..:...:..||||:.:.|
 Worm   651 YSGRMEV----LIKKHRLNVYKSGYWPSE------QELRNEKIPSQKFLQKPGDMVYV------- 698

  Fly  2168 SLATGYVVSESVYFATMSWLDLAKDDFRDIHESCEPAMFSLEQLLFALG-YDQRVNSEALHQMLP 2231
            .:.|.:.|..:.:...:|| ::|:..|              .||..|:. :|..::|:|. .::|
 Worm   699 GIGTFHWVQSNDFAINVSW-NVAQPTF--------------NQLAAAMVIHDHNISSKAT-TLMP 747

  Fly  2232 -------MLNDVCEKES----AAREQLRAAGVTSTE-----KVQAEKGQKAKKQQQPPYKSI--E 2278
                   |..|..|.|.    .||:.:....:..::     .:|.....::.|.:    |||  .
 Worm   748 IEPIVWKMAEDGVEAEDENIFLARKAIMLKSLAKSQFEFDFAIQENMLIRSAKNE----KSIIPV 808

  Fly  2279 SECDL--CRANLYISMVRTEDGNIYCLQHALKNLNNGNIQAKQCKLIYAYNVDDIQQLIRQLQE 2340
            ..|.:  ||..|:..:......|.:||...:|    |.::|.      |:...||..|::...|
 Worm   809 ERCSIQKCREVLFNMITLDNKQNPFCLNCIVK----GKVKAT------AFQRRDIADLVKIFDE 862

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jarid2	NP_648324.1	JmjN	1740..1781	CDD:128818	10/47 (21%)
		ARID	1812..1893	CDD:279697	15/80 (19%)
		JmjC	2066..2181	CDD:202224	22/116 (19%)
		zf-C5HC2	2281..2334	CDD:280996	13/54 (24%)
jmjd-3.2	NP_510405.1	COG5644	40..>191	CDD:227931	41/210 (20%)
		JmjC	577..641	CDD:214721	12/105 (11%)
		JmjC	611..719	CDD:334913	24/125 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0055
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900