Protein Alignment Jarid2 and Kdm5

DIOPT Version :10

• Sequence 1: NP_648324.1
• Gene: Jarid2 / 39103
• FlyBaseID: FBgn0036004
• Length: 2351
• Species: Drosophila melanogaster
• Sequence 2: XP_314337.5
• Gene: Kdm5 / 1275113
• VectorBaseID: AGAMI1_000060
• Length: 1549
• Species: Anopheles gambiae
• Alignment Length: 855
• Identity: 204/855 - (23%)
• Similarity: 348/855 - (40%)
• Gaps: 189/855 - (22%)

  Fly  1647 AASNDAASTTTSLKSLPKASTSAAAGAAAAPG---ASSLVRVNSNSSLFSGSAKSRTAAQTSSTA 1708
            :.|::.|:.:::......:.|..|..:.|:.|   ..|.....|:|||.:.:...||.:.|....
Mosquito    23 SGSDNYANGSSNYGPAGASMTGTAGNSGASAGTMNGGSSRHPQSSSSLSAENIPCRTISATDIRV 87

  Fly  1709 AAV----AKKYKDDTPIKMANNTAFP-----RHDDPTQMV--EAPIFRPTEKEFADPIEFIERIT 1762
            |:|    ..:.:...|:...||...|     :.||....|  |||:|.|:|::|.:|:.:|.:|.
Mosquito    88 ASVDADCLDQQQPQQPMNHHNNPHRPHISLDKCDDFQFNVPPEAPVFEPSEEDFKNPLVYINKIR 152

  Fly  1763 PIAARFGICKIIPPASFKPECRIS-DEMRFTAYNQYVHKMLHRWGPSAKELSAIKKYLATQSIVM 1826
            |.|.:||||||.||:|::|...:. :::.||...|.::::..........|..|.|:...|...:
Mosquito   153 PTAEKFGICKIRPPSSWQPPFTVDVEKLTFTPRIQRLNELEAETRIKLNFLDQIAKFCELQGTTL 217

  Fly  1827 NHPPWIGGMEVDLPRLYHTVQELGGLKEVIEKKKWARVAEEMCIPKLAQDRV--TKLDDIYCKYL 1889
            . .|.:....:||..|:..|.:.|||:.|.:::||::||   |.....|.:.  :.|...|.:.|
Mosquito   218 K-IPMVERKPLDLYTLHKIVNQEGGLEVVTKERKWSKVA---CRMGYQQGKSVGSNLRTHYDRLL 278

  Fly  1890 LPYD-----------TLSPAERQKLFDEVEADWAKREAR----ARRNADRFVNTE---------- 1929
            .|:|           .:.|...:....|.....::::.:    |.|.:.||...:
Mosquito   279 YPFDVYRSGKVVDLANIDPEPSEDCEYEPHCIESRQQVQPPMTAARRSQRFAQQQNNSKPSSTTG 343

  Fly  1930 -----SVSNEEDDLSSDEDE--------------------------ESEEEIDGV---------- 1953
                 ||....|::|..:.|                          .|:||..||
Mosquito   344 SSAGGSVRGSSDEMSPSKKELRHRSMLEFASKLAAAARDQAATNGGASKEEKVGVGGTHGYDPMA 408

  Fly  1954 --------------SM------------------------------ECIVKGRSMPLSQF----- 1969
                          ||                              :|||:..|.|:..|
Mosquito   409 KYICHMCNRGDVEESMLLCDGCDASYHTFCLMPPLQDIPKGDWRCPKCIVEEHSKPVEAFGFEQA 473

  Fly  1970 ---YRIAR-NTMALWFKST--------DPTVNEVEAEFWRHVAVRDSHVCVHSGS-IDSSGWGYG 2021
               |.:.: ..||..|||.        .|| ..||.||||.|:..|..|.|..|: :.:...|.|
Mosquito   474 QREYTLQQFGEMADQFKSNYFNMPVHLVPT-ELVEREFWRIVSSIDEDVTVEYGADLHTMDHGSG 537

  Fly  2022 FP--SPGPKGKGSNYARHPWNLKVLTNNSGSVLRSL-GPVMGVTVPTLHVGMLFSACCWYRDPHG 2083
            ||  |.........||...|||..|.....|:|..: ..:.|:.||.::|||.|:..||:.:.|.
Mosquito   538 FPTKSSSLSSTDQEYAESSWNLNNLPVLDESILGHINADISGMKVPWMYVGMCFATFCWHNEDHW 602

  Fly  2084 LSWIEYLHTGASKLWYGIPDDQSANFRAALTSLIPTHCQNKTIWLPCDTVMVPPHMLTDRGVSLC 2148
            ...|.|||.|..|.|||:|..::.:|..|:.|..|....::...|.....::.|::|.:..|.:.
Mosquito   603 SYSINYLHWGEPKTWYGVPGSRAEDFELAMKSAAPELFHSQPDLLHQLVTIMNPNILMNANVPVY 667

  Fly  2149 RIEQKPGEFIVVFPRAYTSSLATGYVVSESVYFATMSWLDLAKD---DFRDIHESCEPAMFSLEQ 2210
            |.:|..|||:|.|||||.:....||..:|:|.||...|:.:.::   .:..:...|   :||.::
Mosquito   668 RTDQHAGEFVVTFPRAYHAGFNQGYNFAEAVNFAPADWMKMGRECVNHYSKLRRYC---VFSHDE 729

  Fly  2211 LLFALGYD-QRVNSEALHQMLPMLNDVCEKESAAREQLRAAGVTSTEKVQAEKGQKAKKQQQPPY 2274
            |:..:..: .|:|..........:.::.:.|...|:.|...||::.|:...|......:|
Mosquito   730 LVCKMALEPDRLNLGIATACYIDMAEMVDTEKKLRKNLLEWGVSNAEREAFELLTDDARQ----- 789

  Fly  2275 KSIESECDLCRANLYISMVRTE-DGNIYCLQHALKNLNNGNIQAKQCK-------LIYAYNVDDI 2331
                  |::|:...::|.|..: ..|:.||:|.          |:.|:       |.|.|.:|::
Mosquito   790 ------CEICKTTCFLSAVNCKCTKNLACLRHF----------AELCECPPENHTLKYRYTLDEL 838

  Fly  2332 QQLIRQLQEK 2341
            ..::::|:.|
Mosquito   839 PLMVQKLKVK 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Jarid2	NP_648324.1	PHA03247	<157..429	CDD:223021
		Atrophin-1	762..>986	CDD:460830
		JmjN	1740..1781	CDD:128818	21/40 (53%)
		ARID_JARD2	1804..1915	CDD:350634	26/123 (21%)
		cupin_RmlC-like	2066..2181	CDD:477354	40/114 (35%)
		zf-C5HC2	2281..2334	CDD:460750	14/60 (23%)
Kdm5	XP_314337.5	None