DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uch-L5 and UCH2

DIOPT Version :9

Sequence 1:	NP_001261632.1	Gene:	Uch-L5 / 39102	FlyBaseID:	FBgn0011327	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_564858.1	Gene:	UCH2 / 842876	AraportID:	AT1G65650	Length:	330	Species:	Arabidopsis thaliana

Alignment Length:	328	Identity:	156/328 - (47%)
Similarity:	211/328 - (64%)	Gaps:	23/328 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NWCLIESDPGVFTELIREFGCDGAQVEEIWSLDSESFKNLEPIHGLIFLFKWVQEDEPAGKVVLD 71
            :||.||||||||||||::....|.||||::||||:|..||.|::||||||||...::.....:.|
plant     2 SWCTIESDPGVFTELIQQMQVKGVQVEELYSLDSDSLNNLRPVYGLIFLFKWQAGEKDERPTIQD 66

  Fly    72 R-ENIFFAKQVINNACATQAILSLLMNLDHEDIKLGETLTNFKEFCQCFDPYNKGLTLSNASQIR 135
            : .|:|||.|||||||||||||::|:|....||  |..|:..|||.:.|....|||.::|:..||
plant    67 QVSNLFFANQVINNACATQAILAILLNSPEVDI--GPELSALKEFTKNFPSDLKGLAINNSDSIR 129

  Fly   136 TVHNSFARPTLF-ELDTKNQKKDDDVYHFVGYMPIGGRLYELDGLREGPIDLGEIKSEQ---NWI 196
            ..|||||||..| ..:.|...||||||||:.|:|:.|.|||||||:||||.||....:|   .|:
plant   130 AAHNSFARPEPFVPEEQKAATKDDDVYHFISYIPVDGVLYELDGLKEGPISLGPCPGDQTGIEWL 194

  Fly   197 DVVRPIIEKRMQRYSDGEIHFNLMALISDRQRIY-------EQQIEKLLNPAPNAMDTEEDRQ-- 252
            .:|:|:|::|::|||..||.|||:|:|.:|:.||       ::|.|:||..|...:|..|...
plant   195 QMVQPVIQERIERYSQSEIRFNLLAVIKNRKDIYTAELKELQRQREQLLQQANTCVDKSEAEAVN 259

  Fly   253 ---AEISS----LRTYIEYEIQKKKRYKVENVRRKHNYLPFIVELLKILGENGQLMPIYEKAKQR 310
               ||:.|    ....|..|.:|..:::.||:||||||:||:...||:|.|..||.|:.||||::
plant   260 ALIAEVGSGIEAASDKIVMEEEKFMKWRTENIRRKHNYIPFLFNFLKLLAEKKQLKPLIEKAKKQ 324

  Fly   311 ALE 313
            ..|
plant   325 KTE 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uch-L5	NP_001261632.1	Peptidase_C12_UCH37_BAP1	8..222	CDD:187738	116/218 (53%)
UCH2	NP_564858.1	Peptidase_C12_UCH37_BAP1	3..220	CDD:187738	116/218 (53%)
UCH2	NP_564858.1	UCH_C	269..314	CDD:407868	17/44 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	212	1.000	Domainoid score	I779
eggNOG	1	0.900	-	-		E1_KOG2778
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9326
Inparanoid	1	1.050	287	1.000	Inparanoid score	I846
OMA	1	1.010	-	-		QHG53985
OrthoDB	1	1.010	-	-		D1363547at2759
OrthoFinder	1	1.000	-	-		FOG0001783
OrthoInspector	1	1.000	-	-		mtm1028
orthoMCL	1	0.900	-	-		OOG6_102753
Panther	1	1.100	-	-	LDO	PTHR10589
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1137
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840